Data for (Study ST003606)

(Analysis AN005925)

Values for each metabolite have been scaled by dividing by the mean across all factors

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

MetaboliteF1F2F3F4F5F6F7F8F9F10F11F12F13F14F15F16F17F18F19F20
1-4-beta-D-Xylan 1.2442 1.7296 0.9155 0.9581 0.9426 1.0702 0.4746 0.4808 1.2559 3.4796 1.7047 2.7343 0.8260 0.6788 0.8008 0.7547 0.5439 0.5033 0.3875 0.3957
2/3-Phospho-D-glycerate 0.9561 1.5321 0.3514 0.5602 1.4285 1.2163 0.5751 0.7368 0.5558 0.3374 0.0404 0.2560 2.0818 1.2695 0.3559 0.4330 1.4536 1.3022 2.4398 2.0678
2-Hydroxyglutarate/Citramalate 1.3754 2.3267 1.0218 1.2225 1.4215 1.7630 0.5247 0.5078 0.5910 1.0149 1.9599 2.2240 0.8754 0.8171 0.7715 0.8389 0.5898 0.7097 0.3729 0.4196
2-Oxoglutaramate 0.3985 1.2898 0.9823 1.5829 0.9651 0.4580 1.2786 0.8644 0.7864 0.6909 1.2312 0.0886 0.2279 0.6016 4.6701 0.9771 0.9033 1.1172 0.9913 0.6474
2-Oxoglutarate 1.0820 1.2981 1.4338 1.2741 0.9050 1.1171 0.9066 0.8023 0.0873 0.1347 2.7043 2.6603 0.8776 0.5074 1.3726 1.2978 0.3078 0.2376 0.5072 0.5659
3-Phosphonooxypyruvate 1.2381 1.7553 1.1149 0.9986 1.3139 1.2142 0.8919 0.7636 0.9618 1.1596 1.0453 0.9965 0.8000 1.0385 0.8148 0.9491 1.1041 1.0759 0.9382 0.6617
3-Sulfino-L-alanine 1.2182 2.0955 1.1657 1.2392 1.5642 1.3822 0.7148 0.6204 1.0505 1.0563 0.9703 1.1017 0.7202 0.8076 0.7485 0.7735 1.4869 1.2493 0.7802 0.4618
4-Pyridoxate 0.6852 0.6164 0.2947 0.3234 0.5367 0.5073 0.7378 0.3420 0.5669 0.2293 0.1578 0.1946 0.2425 0.2676 5.6687 0.2861 0.5166 0.6561 4.3624 3.3224
5-6-Dihydrothymine 1.7099 1.8979 1.1218 1.1497 1.4892 1.3760 0.7932 0.5908 1.3431 1.3997 1.2774 1.8073 0.9280 0.7656 0.9724 0.6364 0.6572 0.6069 0.6338 0.4320
5-Aminopentanoate 0.5048 0.8110 0.3410 0.2709 0.5964 0.5353 0.3426 0.2619 0.9227 0.6101 0.3282 0.3096 0.5059 0.5187 14.7082 0.3030 0.4605 0.7938 0.4056 0.2951
(5Z-8Z-11Z-14Z-17Z)-Icosapentaenoic acid 1.0233 1.2853 0.5744 0.6958 0.9471 1.1361 0.6597 0.7223 2.9122 2.1123 0.9674 1.3318 0.5368 0.4609 0.8931 0.7546 0.6211 0.8959 1.1770 1.1695
(7Z-10Z-13Z-16Z-19Z)-Docosa-7-10-13-16-19-pentaenoic acid 1.2301 1.4610 0.6076 0.6137 1.0596 1.0662 0.7199 0.5981 3.0267 2.2235 0.7973 1.0150 0.7146 0.7974 0.8784 0.7003 0.9828 1.0951 1.0041 0.9396
(8Z-11Z-14Z)-Icosatrienoic acid 0.9234 1.0753 0.6725 0.7185 0.9595 0.9000 0.9028 0.7467 2.0400 1.4203 0.8854 1.0490 0.6841 0.7846 1.1300 0.9889 0.9894 1.3894 1.3113 1.0673
ADP-D-ribose 1.1604 1.9562 0.5714 0.2274 1.5810 1.7352 0.7704 0.4776 1.7599 1.8622 1.3485 1.2247 1.2053 1.2516 0.6013 0.5140 1.1754 1.3632 1.0684 0.7251
alpha-D-Glucosamine 1-phosphate 1.5487 2.8249 1.0524 0.9376 1.7936 1.8768 0.7144 0.6367 1.2812 1.4429 0.4599 0.7084 0.7674 0.5446 0.9119 0.3552 0.8169 0.7752 1.5702 0.7464
alpha-D-Ribose 1-phosphate 1.5498 1.5902 0.5110 0.6736 1.5712 1.3950 0.3975 0.5459 2.3478 2.2245 0.8596 0.8630 1.2216 1.2811 0.4927 0.5768 1.2484 1.0785 0.6775 0.7855
AMP 1.6332 1.9795 0.4255 0.5413 1.7335 1.5218 0.3568 0.2762 1.8727 3.2899 0.8766 1.9238 1.2801 1.0150 0.4825 0.5177 1.4603 1.1645 0.3869 0.3495
Argininosuccinate 2.6625 2.4069 0.4316 1.3388 2.3130 1.3233 0.9656 1.7304 0.3339 0.2681 0.1491 0.2724 0.9731 0.3744 0.6831 0.4882 0.5885 0.2770 0.9720 0.7520
Ascorbate 1.0961 1.1499 1.0857 1.5112 0.8389 0.9632 0.5047 0.6734 0.0772 0.0617 1.3876 1.7311 1.3739 1.1718 1.7957 1.8884 0.4892 0.3916 0.3848 0.5684
Citrate 1.2097 0.6745 0.4018 0.5072 1.2030 0.6234 0.4821 0.5982 0.8261 1.4858 0.3739 0.9823 2.1112 0.9557 0.8080 0.5471 1.1940 0.6865 2.5644 2.0979
CMP 1.2882 1.7492 0.5339 0.4284 1.0346 1.3063 0.4817 0.3954 1.7591 2.0525 0.7821 1.0901 1.2732 1.1217 0.8631 0.8184 1.3081 1.1405 1.0891 1.1263
Cytidine 2.1786 2.8012 0.8821 1.2957 2.2331 2.3472 0.7409 0.7027 0.9104 1.1760 0.2925 0.4123 0.7977 0.8623 0.6743 0.5730 0.9583 0.9546 0.2481 0.3702
dAMP 0.7664 0.9701 0.3485 0.5254 0.6089 0.7209 0.2158 0.7288 NA NA NA NA 2.3758 1.9545 1.7165 0.9937 0.9143 0.9296 0.9054 1.1164
D-Arabitol 0.8048 0.8940 0.5834 0.9820 0.9712 0.7199 0.2842 0.4957 0.0849 0.0990 0.0546 0.1251 1.6587 1.5485 1.4393 1.8583 1.7925 2.0399 1.0409 1.4608
Dehydroascorbate 0.7900 0.6008 0.1318 0.2960 0.6058 0.5016 0.3390 0.4227 0.9342 0.8319 0.3119 0.4689 0.5714 0.4603 9.8283 0.3676 0.4023 0.5832 0.7675 1.5285
D-Glucono-1-5-lactone 6-phosphate 1.0344 0.8329 0.8029 0.6927 0.8911 1.0284 0.8692 1.1770 0.8054 0.8856 0.6124 1.0310 1.7130 1.1906 1.2284 0.9754 1.1501 0.7628 1.0485 1.2034
D-Glucose 0.8605 1.2419 0.8916 0.9206 1.2652 1.0579 0.8585 0.8858 0.7379 0.8531 0.6520 1.1918 1.3773 1.0955 1.0260 1.0296 1.0647 1.3391 1.0726 0.9131
Dimethylglycine 0.9519 1.1415 0.7494 1.1264 1.6065 0.9735 0.5489 0.6604 0.7504 0.8984 0.6367 0.7805 0.9373 1.0371 0.9573 1.4886 1.5764 1.5729 0.7915 0.7632
Diphosphate 0.7859 0.9807 0.5845 0.8432 1.0804 0.7711 0.6616 1.1639 0.8756 1.1204 0.4276 0.6032 1.7181 1.2569 1.0201 1.1133 1.2852 1.0616 1.0850 1.1719
Docosahexaenoic acid 1.4257 1.6126 0.5434 0.5867 1.2790 1.2304 0.6633 0.5791 2.9292 2.2314 0.7431 0.8698 0.8882 0.9021 0.8001 0.6420 1.0737 1.1509 0.9157 0.7956
Dodecanoic acid 0.9219 1.0177 1.0452 0.9835 0.9648 0.8465 1.2731 0.8927 0.9211 0.9231 0.9348 0.9598 0.8545 0.9887 1.2196 0.9665 0.9507 1.8812 0.9728 0.8678
Eicosapentaenoic acid 1.0233 1.2853 0.5744 0.6958 0.9471 1.1361 0.6597 0.7223 2.9122 2.1123 0.9674 1.3318 0.5368 0.4609 0.8931 0.7546 0.6211 0.8959 1.1770 1.1695
Eicosatetraenoic acid 0.9704 1.0291 0.6036 0.7599 0.9131 0.9652 0.8874 0.8054 2.1072 1.4708 0.9857 1.0465 0.6417 0.6934 0.8361 0.8920 0.9292 1.0865 1.3622 1.3164
Ethanolamine phosphate 1.7745 2.3267 0.7473 0.8641 1.5942 1.5514 0.5090 0.6603 1.7653 2.5155 0.7701 1.2212 1.2919 0.9174 0.6559 0.7259 0.8283 0.6337 0.2450 0.3151
Fumarate 1.1458 1.3516 0.4847 1.1726 0.9869 0.9718 1.0349 1.5398 1.0124 1.2178 0.3145 0.6830 1.2943 0.9438 1.3273 0.7551 0.8428 0.6656 0.7333 0.9566
fumarate 13C4 NA 0.0636 NA 0.8362 0.2570 0.5958 0.0732 1.3726 NA NA NA NA 1.2535 0.6877 0.5190 1.5618 0.7102 0.7072 0.4880 1.2360
Glutathione 1.6052 1.8919 0.5923 0.7640 1.2167 1.3005 0.5001 0.5794 1.5690 2.4730 0.5478 1.2577 1.3853 1.0149 0.5052 0.7406 1.0079 0.7414 0.8941 0.8432
Glutathione disulfide 1.7418 2.1454 0.6479 0.8263 1.7800 0.8402 0.5041 0.4536 2.2189 2.2427 1.3784 0.6699 0.2512 1.3319 0.2124 0.7099 0.7997 0.4112 0.5260 0.5123
Glycerol 3-phosphate 1.8902 1.9917 0.9260 1.0127 1.9628 1.5096 0.6301 0.7232 0.7719 0.5736 0.4162 0.7615 1.5149 0.8437 1.1734 0.8029 1.0052 0.8806 0.8078 0.7502
GMP 1.0014 1.9946 0.3710 0.5336 1.0940 1.4412 0.3197 0.3890 2.6148 3.2351 0.9087 1.0982 0.9278 0.9846 0.5122 0.6903 1.2290 0.9163 0.9123 0.8609
Heptanoic acid 0.8223 1.0998 1.0677 1.1378 1.0167 1.0595 1.0371 0.9226 1.1170 1.0201 1.0243 1.0083 0.7762 0.9402 1.0781 0.9637 0.9619 1.1312 0.9971 0.9084
Hexadecanoic acid 0.9725 1.1062 0.9570 1.0347 0.9927 0.9491 1.2498 0.8563 0.9887 1.0440 0.9902 0.8813 0.8108 0.9295 1.4965 0.8567 1.0423 1.5087 1.0016 0.8576
Hexadecenoic acid 0.5408 0.8295 0.4074 0.3972 0.5364 0.5328 5.5228 0.3524 0.6539 0.5564 0.3036 0.3484 0.4649 0.5300 1.1128 0.3975 0.5821 8.3118 0.4526 0.4160
Hexanoic acid (caproate) 0.8446 1.0967 0.9798 1.1554 0.9877 1.0576 1.1186 0.8739 1.0495 1.0152 1.1607 1.1083 0.7373 0.9629 1.0163 0.9919 0.8943 1.3350 0.9104 0.8611
Hypotaurine 2.1443 1.9773 0.6877 0.8681 1.9861 1.4887 0.5239 0.4402 2.2960 3.0945 1.1380 1.6379 0.9316 0.6112 0.4779 0.6367 0.6876 0.4160 0.1864 0.2185
Hypoxanthine 0.9971 1.2235 0.2954 0.4481 1.1983 0.9993 0.2643 0.3102 3.0161 2.5846 1.0077 0.9561 0.8829 0.9828 4.4627 0.5329 0.8030 0.9715 0.5074 0.5004
IMP 1.2214 1.6094 0.3876 0.6862 1.9598 1.0062 0.1921 0.2648 3.1158 2.7636 1.2884 1.7915 0.6822 0.5757 1.2096 0.7728 0.7100 0.6055 0.5736 0.6937
Inosine 0.9731 1.2191 0.2729 0.3619 1.1152 1.0563 0.1517 0.3186 5.3466 4.0299 1.4883 1.1371 0.7106 1.0143 0.6264 0.6612 0.7720 0.8237 0.4046 0.4547
Itaconate 1.8948 2.5492 1.0517 1.0303 1.6824 1.7015 0.6481 0.6555 1.1769 2.1580 0.6652 0.9651 1.2960 0.9510 0.5910 0.5842 1.0068 0.7433 0.2513 0.3018
itaconate 13C5 0.5895 0.7987 0.4548 0.4209 0.6283 0.8986 0.4183 0.4286 0.3425 0.2661 0.2356 0.2635 1.4877 1.8682 1.5343 2.3902 1.5212 2.2297 1.1844 1.3083
Lactate 1.3983 1.7376 0.6444 0.9863 1.5281 1.2765 0.5840 0.7632 0.7645 0.5291 0.2912 0.7288 1.0166 0.6197 4.6757 0.7343 0.7878 0.9148 0.4336 0.6887
L-Cysteate 1.3863 2.4314 1.3296 1.3328 1.6148 1.0957 0.6798 0.6512 1.0113 0.9282 1.2259 0.7741 0.3099 0.7576 0.5602 0.7350 1.4665 1.4117 0.6641 0.4461
Linoleate 0.7635 1.0050 0.5099 0.4984 0.6982 0.6668 1.2627 0.3964 1.0796 0.8122 0.3712 0.4769 0.5847 0.5973 3.6903 0.4727 0.7738 7.1480 0.6046 0.4704
Malate 1.2195 1.3506 0.4755 1.2691 1.1566 1.0106 1.0866 1.6048 0.9318 1.0484 0.2658 0.6436 1.4174 0.9851 0.6494 0.7766 0.8408 0.6933 0.6552 1.0223
malate 13C4 0.3402 0.3462 0.2104 0.7497 0.4115 0.3932 0.2426 1.6401 NA NA 0.0152 NA 1.5770 1.1053 0.9403 1.5075 1.1880 0.9212 0.5126 1.8769
Maltose 0.3850 0.8785 0.7872 0.6624 0.6154 0.8775 1.9665 0.6764 0.5561 0.2925 0.7974 0.9416 0.1624 0.5169 0.8836 0.4355 0.6503 3.5531 3.4812 1.4536
Mannitol 1.2356 1.3139 0.8227 1.0439 1.7132 1.1265 0.5553 1.0581 0.2790 0.6117 0.1501 0.3049 0.6961 0.5817 5.9723 1.1934 0.5055 0.5937 0.2468 0.4007
N-Acetylneuraminate 1.2443 1.7492 0.8551 0.4537 0.7881 0.8934 0.3878 0.2838 1.6080 1.7488 0.9308 1.0530 1.7626 1.7826 1.5752 1.1270 1.2033 1.2313 0.7913 0.5905
N-Glycoloyl-neuraminate 1.2895 1.4156 1.0635 0.5726 0.9544 0.8257 0.3898 0.3688 1.7234 1.5320 1.1407 1.1070 1.7390 1.3472 1.5276 1.1852 1.2887 0.9538 0.7403 0.5713
Nonanoic acid (pelargonate) 0.8505 1.0713 1.1026 1.1539 0.9677 0.9806 1.0064 0.9632 1.1146 1.0295 1.0145 1.0092 0.7770 0.9931 1.0526 0.9764 1.0641 1.1737 1.0692 0.7879
Octadecanoic acid (stearic acid) 1.0603 0.9514 0.8779 0.8478 0.9883 1.0159 0.8916 1.0950 0.9391 1.0116 0.8483 0.7619 0.9328 0.8409 1.3465 0.9788 0.9322 1.0901 0.9688 1.3108
Octadecatrienoic acid (linolenic acid) 0.3378 0.5107 0.2584 0.3285 0.3213 0.3147 0.9351 0.2929 0.5160 0.4553 0.2820 0.2945 0.3305 0.2990 4.7505 0.3120 0.3749 12.1204 0.3129 0.3177
Octadecenoic acid (oleic acid) 0.8215 1.2103 0.6733 0.5858 0.8162 0.9301 1.5027 0.5354 1.1300 1.0624 0.5371 0.6163 0.7804 0.8233 2.4505 0.6880 1.0234 4.1358 1.0218 0.6757
Octanoic acid (caprylate) 0.8592 1.0628 1.0502 1.1754 1.0016 1.0101 1.0070 0.9098 0.9992 1.0074 1.0602 1.0784 0.8410 0.8672 1.0921 0.9821 0.9131 1.2997 1.0664 0.8403
Phosphate 0.8803 0.9668 0.7914 0.9460 1.0346 0.8890 0.8759 1.1044 0.9619 1.0090 0.6771 0.7665 1.3216 1.1030 1.0109 1.0733 1.0733 1.0367 1.0804 1.0999
Pyruvate 0.8463 1.1655 0.7913 1.2012 0.7924 0.9004 0.7909 0.7284 0.6127 1.4280 1.0508 1.4146 1.0265 0.9147 2.5558 1.4131 0.4703 0.5710 0.5534 0.7069
Sedoheptulose 1-phosphate 2.6058 3.2312 0.9098 1.3392 2.4490 2.1962 0.6393 1.0289 0.9255 0.5981 0.3358 0.4758 0.5040 0.4704 0.2111 0.3017 0.4244 0.3757 0.8544 0.8132
S-Glutathionyl-L-cysteine 1.5058 2.9917 0.8934 1.1528 1.7519 1.1626 0.5947 0.5764 1.2737 1.8519 0.8053 1.1112 0.5622 0.5394 0.3745 0.6773 1.0944 0.9415 0.7894 0.6319
sn-glycero-3-Phosphoethanolamine 2.0064 2.7365 0.8840 1.2372 2.0984 2.2088 0.7492 0.8975 0.7816 1.0838 0.3233 0.4681 0.9222 0.8333 0.4667 0.7304 0.8766 0.8119 0.3145 0.4639
Succinate 1.0473 1.3117 0.6199 0.4086 0.8974 0.9316 1.1552 0.5996 1.2434 2.6091 0.8390 0.6444 1.1071 0.9780 0.9686 0.4896 0.9861 1.6210 2.0875 1.1963
Taurine 1.8093 1.9600 0.6994 0.9999 1.6633 1.3827 0.4683 0.5237 2.4709 2.6737 1.3467 1.7156 0.7811 0.6750 0.4858 0.7091 0.6916 0.5278 0.1541 0.2652
Tetradecanoic acid 0.8616 1.0356 0.8802 0.8445 0.8618 0.8796 1.6949 0.8549 0.8346 0.8872 0.8623 0.7758 0.8019 0.8953 1.1619 0.8294 1.0172 3.2544 0.9048 0.7816
Tetradecenoic acid 0.5052 0.7100 0.4221 0.4930 0.5176 0.4356 4.3808 0.4146 0.4984 0.4768 0.4451 0.4295 0.4669 0.5303 1.2786 0.4325 0.4904 8.9156 0.4936 0.5185
trans-4-Hydroxy-L-proline 1.4388 1.8241 0.8593 1.2005 1.4529 1.2090 0.6338 0.6127 1.0418 1.2345 1.5548 1.0654 0.8329 0.8371 1.7463 0.8391 0.8833 0.8454 0.4952 0.5099
UDP-glucose 1.1681 1.1394 0.4762 0.5267 1.3253 0.9161 0.5395 0.3630 1.4817 1.4272 0.7149 1.0966 2.3240 1.5581 0.7334 0.6858 2.3155 1.3575 1.0580 0.8680
UDP-N-acetyl-D-glucosamine 1.1429 1.2045 0.5154 0.4414 0.9579 0.8132 0.5520 0.4302 1.8564 2.1737 0.9602 1.4473 1.7637 1.0245 0.7880 0.6037 1.5840 1.0933 1.4888 1.0821
UMP 1.5313 1.8055 0.3473 0.4602 1.1332 1.3509 0.2387 0.2914 2.6053 3.3548 1.0693 1.3064 1.3931 1.2297 0.5474 0.6040 1.3478 1.0043 0.4797 0.6109
Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Factors:

F1time (h):18 | E coli treatment:dead | genotype:Cre
F2time (h):18 | E coli treatment:dead | genotype:Cre KRAS +/+
F3time (h):18 | E coli treatment:dead | genotype:HRAS +/+
F4time (h):18 | E coli treatment:dead | genotype:WT
F5time (h):18 | E coli treatment:live | genotype:Cre
F6time (h):18 | E coli treatment:live | genotype:Cre KRAS +/+
F7time (h):18 | E coli treatment:live | genotype:HRAS +/+
F8time (h):18 | E coli treatment:live | genotype:WT
F9time (h):18 | E coli treatment:none | genotype:Cre
F10time (h):18 | E coli treatment:none | genotype:Cre KRAS +/+
F11time (h):18 | E coli treatment:none | genotype:HRAS +/+
F12time (h):18 | E coli treatment:none | genotype:WT
F13time (h):6 | E coli treatment:dead | genotype:Cre
F14time (h):6 | E coli treatment:dead | genotype:Cre KRAS +/+
F15time (h):6 | E coli treatment:dead | genotype:HRAS +/+
F16time (h):6 | E coli treatment:dead | genotype:WT
F17time (h):6 | E coli treatment:live | genotype:Cre
F18time (h):6 | E coli treatment:live | genotype:Cre KRAS +/+
F19time (h):6 | E coli treatment:live | genotype:HRAS +/+
F20time (h):6 | E coli treatment:live | genotype:WT
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