Data for (Study ST003665)
(Analysis AN006022)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 |
|---|---|---|---|
| 1,3-diphopshateglycerate | 0.5333 | 1.0904 | 1.6549 |
| 1-Methyladenosine | 1.1671 | 1.2108 | 0.6440 |
| 1-Methyl-Histidine | 1.4041 | 0.6066 | 0.5906 |
| 2,3-dihydroxybenzoic acid | 0.9843 | 0.8811 | 1.0830 |
| 2,3-Diphosphoglyceric acid | 0.6536 | 1.7444 | 1.1474 |
| 2-Aminooctanoic acid | 1.5824 | 0.4250 | 0.4139 |
| 2-dehydro-D-gluconate | 1.2520 | 1.0668 | 0.5886 |
| 2-deoxyglucose-6-phosphate | 0.9796 | 1.4375 | 0.8119 |
| 2-Hydroxy-2-methylbutanedioic acid | 0.8421 | 1.2198 | 1.1270 |
| 2-hydroxygluterate | 0.8460 | 1.1716 | 1.1452 |
| 2-Isopropylmalic acid | 0.9112 | 0.9730 | 1.1467 |
| 2-ketohaxanoic acid | 0.9910 | 0.8415 | 1.0927 |
| 2-keto-isovalerate | 0.9277 | 1.1029 | 1.0569 |
| 2-oxo-4-methylthiobutanoate | 0.8085 | 1.8184 | 0.7562 |
| 2-oxobutanoate | 0.9621 | 0.7585 | 1.1776 |
| 3-hydroxybuterate | 1.0305 | 0.9873 | 0.9606 |
| 3-methylphenylacetic acid | 0.9142 | 1.1033 | 1.0770 |
| 3-phosphoglycerate | 0.8943 | 1.2114 | 1.0528 |
| 3-phospho-serine | 1.7744 | 0.1852 | 0.2458 |
| 3-S-methylthiopropionate | NA | NA | NA |
| 4-aminobutyrate | 1.4391 | 0.5814 | 0.5507 |
| 4-phosphopantothenate | 0.7336 | 0.7476 | 1.5258 |
| 4-Pyridoxic acid | 1.0214 | 1.2758 | 0.8300 |
| 5-methoxytryptophan | 1.2209 | 0.8210 | 0.7582 |
| 5-methyl-THF | 0.8807 | 1.2099 | 1.0740 |
| 5-phosphoribosyl-1-pyrophosphate | 0.3006 | 1.8968 | 1.6006 |
| 6-phospho-D-gluconate | 0.1934 | 1.8442 | 1.7879 |
| 7,8-dihydrofolate | 0.7778 | 1.0003 | 1.2219 |
| 7-methylguanosine | 1.0214 | 0.6758 | 1.1299 |
| acadesine | 1.6268 | 0.4066 | 0.3566 |
| acetoacetate | 0.7368 | 0.9504 | 1.4195 |
| acetoacetyl-CoA-posi | 1.0862 | 0.4768 | 1.1324 |
| Acetylcarnitine DL | 1.2019 | 0.7433 | 0.8254 |
| acetyl-CoA-posi | 0.8448 | 0.7215 | 1.3721 |
| Acetyllysine | 1.3421 | 0.6619 | 0.6559 |
| acetylphosphate | 0.9554 | 0.9006 | 1.1167 |
| aconitate | 0.5068 | 1.4858 | 1.4968 |
| adenine | 1.0220 | 1.0245 | 0.9548 |
| adenosine | 1.9707 | 0.0268 | 0.0305 |
| adenosine 5-phosphosulfate | 1.5595 | 0.4502 | 0.4357 |
| Adenylosuccinate | 0.2026 | 1.6734 | 1.8593 |
| ADP-D-glucose | 1.1697 | 0.8715 | 0.8097 |
| ADP-nega | 1.5937 | 0.4245 | 0.3972 |
| a-ketoglutarate | 1.2148 | 0.7883 | 0.7836 |
| alanine | 1.3926 | 0.6055 | 0.6084 |
| allantoate | 0.6069 | 1.1567 | 1.5113 |
| allantoin | 1.0483 | 0.7034 | 1.0759 |
| Aminoadipic acid | 1.0003 | 0.9490 | 1.0251 |
| aminoimidazole carboxamide ribonucleotide | 1.1032 | 0.7563 | 0.9671 |
| AMP | 1.4521 | 0.5478 | 0.5479 |
| anthranilate | 0.9039 | 1.4117 | 0.9383 |
| arginine | 1.1161 | 0.7852 | 0.9333 |
| arginosuccinic acid | 1.4990 | 0.5056 | 0.4987 |
| Ascorbic acid | 1.5760 | 0.5253 | 0.3733 |
| asparagine | 1.5165 | 0.4748 | 0.4878 |
| aspartate | 0.8703 | 1.1137 | 1.1377 |
| ATP-nega | 1.0700 | 0.9450 | 0.9225 |
| Atrolactic acid | 0.7469 | 0.9548 | 1.4022 |
| betaine | 0.5143 | 1.5216 | 1.4678 |
| betaine aldehyde | 1.3616 | 0.6120 | 0.6516 |
| biotin | 1.0347 | 0.9645 | 0.9657 |
| Carbamoyl phosphate | 0.8693 | 1.1060 | 1.1430 |
| carnitine | 1.3820 | 0.6439 | 0.6051 |
| CDP-choline | 0.2696 | 1.7706 | 1.7103 |
| CDP-ethanolamine | 0.4343 | 1.3552 | 1.6710 |
| CDP-nega | 1.2988 | 0.6554 | 0.7241 |
| Cellobiose | 1.0000 | NA | NA |
| cholesterol | 0.6363 | 0.4875 | 1.8018 |
| cholesteryl sulfate | 0.8152 | 0.4264 | 1.5640 |
| Cholic acid | 1.0000 | NA | NA |
| choline | 0.3057 | 1.8031 | 1.6399 |
| Citraconic acid | 0.6612 | 1.3512 | 1.3327 |
| citrate | 0.6992 | 1.2707 | 1.3159 |
| citrate-isocitrate | 0.6355 | 1.3517 | 1.3709 |
| citrulline | 1.1106 | 0.9244 | 0.8719 |
| CMP | 1.3814 | 0.6044 | 0.6257 |
| coenzyme A-posi | 1.0481 | 0.8304 | 1.0127 |
| creatine | 1.2527 | 0.7411 | 0.7503 |
| Creatinine | 1.2539 | 0.7567 | 0.7409 |
| CTP-nega | 0.7155 | 1.3525 | 1.2505 |
| cyclic-AMP | 1.2562 | 0.5655 | 0.8330 |
| cyclic bis(3->5) dimeric GMP | NA | NA | NA |
| cystathionine | 1.1723 | 0.8195 | 0.8318 |
| cysteine | 0.2369 | 3.8878 | 0.7007 |
| cysteine sulfinate | NA | 1.0000 | NA |
| Cystine | 0.1074 | 4.9234 | 0.3772 |
| cytidine | 0.7590 | 1.2676 | 1.2277 |
| cytosine | 1.0226 | 0.9676 | 0.9823 |
| dAMP | 0.8879 | 1.1439 | 1.0962 |
| dATP-nega | 0.8725 | 1.1137 | 1.1343 |
| dCDP-nega | 1.2050 | 0.8284 | 0.7783 |
| dCMP | 0.6672 | 1.3667 | 1.3159 |
| dCTP-nega | 0.9824 | 1.0045 | 1.0241 |
| dehydroascorbic acid | 1.0501 | 1.3303 | 0.7598 |
| deoxyadenosine | 1.0812 | 1.0308 | 0.8629 |
| Deoxycholic acid | NA | NA | NA |
| deoxyguanosine | 0.9900 | 1.1126 | 0.9587 |
| deoxyinosine | 1.0610 | 0.7122 | 1.0524 |
| deoxyribose-phosphate | 0.7781 | 1.0758 | 1.2949 |
| deoxyuridine | 1.2306 | NA | 0.7694 |
| dephospho-CoA-nega | 1.3889 | 1.1109 | 0.7501 |
| dephospho-CoA-posi | 0.6751 | NA | 1.4874 |
| D-erythrose-4-phosphate | 0.8071 | 0.9916 | 1.2936 |
| dGDP-nega | 1.5837 | 0.4171 | 0.4159 |
| D-glucarate | 1.5554 | 0.3706 | 0.4816 |
| D-gluconate | 0.3915 | 1.6661 | 1.5797 |
| D-glucono-?-lactone-6-phosphate | 0.7277 | 1.2653 | 1.2758 |
| D-glucosamine-1-phosphate | 0.6696 | 1.9943 | 0.9984 |
| D-glucosamine-6-phosphate | 0.9153 | 1.1468 | 1.0537 |
| D-glyceraldehdye-3-phosphate | 0.9243 | 0.8916 | 1.1677 |
| dGMP | 1.0508 | 1.0082 | 0.9451 |
| dGTP | 1.0799 | 0.9603 | 0.9000 |
| dihydroorotate | 0.9465 | 0.9520 | 1.1043 |
| dihydroxy-acetone-phosphate | 1.3754 | 0.5042 | 0.6848 |
| Diiodothyronine | 1.0000 | NA | NA |
| dimethylglycine | 0.3452 | 1.3091 | 1.8276 |
| DL-Pipecolic acid | 1.2410 | 0.7430 | 0.7671 |
| D-sedoheptulose-1-7-phosphate | 0.9842 | 0.7976 | 1.1249 |
| dTDP-nega | 1.3827 | 0.7976 | 0.5271 |
| dTMP | 0.9386 | 0.7693 | 1.2075 |
| dTMP-nega | 0.7224 | 1.3986 | 1.2172 |
| dTTP-nega | 0.7965 | 0.9664 | 1.3221 |
| dUMP-nega | 0.8699 | 0.9755 | 1.2074 |
| dUTP-nega | 1.0984 | 0.8144 | 0.9453 |
| ethanolamine | 0.8828 | 1.3251 | 1.0132 |
| FAD | 1.0108 | 1.0492 | 0.9591 |
| Flavone | 0.7109 | 1.3315 | 1.2679 |
| FMN | 1.5800 | 0.7401 | 0.2599 |
| folate | 0.7539 | 1.4715 | 1.1334 |
| fructose-1,6-bisphosphate | 0.8192 | 1.2117 | 1.1654 |
| fructose-6-phosphate | 0.7290 | 1.0345 | 1.3893 |
| fumarate | 0.9669 | 1.0734 | 1.0130 |
| GDP-nega | 1.6610 | 0.3384 | 0.3394 |
| Geranyl-PP | 0.7183 | 1.0892 | 1.3779 |
| glucono-?-lactone | 0.5325 | 1.7481 | 1.3272 |
| glucosamine | 0.9739 | 1.0129 | 1.0326 |
| glucose-1-phosphate | 0.7928 | 1.7453 | 0.9382 |
| glucose-6-phosphate | 0.7347 | 1.3497 | 1.2231 |
| glutamate | 0.8407 | 1.1932 | 1.1423 |
| glutamine | 1.1729 | 0.8542 | 0.8136 |
| glutathione | 1.0719 | 0.8238 | 0.9803 |
| glutathione disulfide-nega | 0.7871 | 1.2546 | 1.1920 |
| glutathione disulfide-posi | 0.7998 | 1.2932 | 1.1537 |
| glutathione-nega | 0.9969 | 0.8778 | 1.0658 |
| gluterate | 1.5087 | 0.4655 | 0.5042 |
| glycerate | 1.5112 | 0.4936 | 0.4864 |
| glycerol 3-phosphate | 1.2651 | 0.6455 | 0.7796 |
| Glycerophosphocholine | 0.3861 | 1.6148 | 1.6135 |
| glycine | NA | NA | NA |
| glycolate | NA | NA | 1.0000 |
| glyoxylate | 1.0416 | NA | 0.9376 |
| GMP | 1.8514 | 0.1535 | 0.1462 |
| GTP-nega | 1.0141 | 1.0284 | 0.9646 |
| Guanidoacetic acid | 1.1110 | 0.7613 | 0.9529 |
| guanine | 1.0000 | NA | NA |
| guanosine | 1.5069 | 0.6215 | 0.4289 |
| guanosine 5-diphosphate,3-diphosphate | 0.7883 | 1.2770 | 1.1790 |
| hexose-phosphate | 0.8390 | 1.0646 | 1.2091 |
| histidine | 1.3783 | 0.6058 | 0.6297 |
| histidinol | 0.8002 | 1.1998 | NA |
| HMG-CoA_pos | 0.5485 | 1.5698 | 1.3924 |
| homocysteic acid | 1.0908 | NA | 0.9092 |
| homocysteine | 1.0989 | 0.8490 | 0.9272 |
| homoserine | 1.3813 | 0.7887 | 0.5337 |
| Hydroxyisocaproic acid | 1.3403 | 0.2320 | 1.0437 |
| Hydroxyphenylacetic acid | 0.9536 | 0.7517 | 1.1937 |
| hydroxyphenylpyruvate | NA | 1.0000 | NA |
| hydroxyproline | 1.1522 | 0.7106 | 0.9163 |
| hypoxanthine | 1.7016 | 0.1546 | 0.3702 |
| IDP-nega | 1.5719 | 0.4426 | 0.4209 |
| Imidazoleacetic acid | 0.4505 | 1.1972 | 1.7256 |
| IMP | 1.4555 | 0.5074 | 0.5631 |
| indole | 1.1321 | 0.9444 | 0.8296 |
| Indole-3-carboxylic acid | 1.1658 | 0.8184 | 0.8420 |
| Indoleacrylic acid | 1.1101 | 0.9562 | 0.8568 |
| inosine | 1.0869 | 1.5506 | 0.5944 |
| isocitrate | 0.2226 | 1.8142 | 1.7590 |
| itaconic acid | 0.6748 | 1.4301 | 1.2728 |
| Kynurenic acid | 0.8996 | 1.0125 | 1.1443 |
| Kynurenine | 1.4976 | 0.3979 | 0.5546 |
| lactate | 0.9102 | 1.0766 | 1.0964 |
| L-arginino-succinate | 1.4952 | 0.3702 | 0.5720 |
| leucine-isoleucine | 1.1642 | 0.8384 | 0.8345 |
| lipoate | 1.3334 | 0.6999 | 0.3000 |
| lysine | 1.1979 | 0.8128 | 0.7968 |
| malate | 1.0267 | 1.0085 | 0.9557 |
| Maleic acid | 0.9392 | 1.0100 | 1.0862 |
| malonyl-CoA-posi | 1.0331 | 1.0304 | 0.9351 |
| methionine | 1.2240 | 0.7300 | 0.7990 |
| Methionine sulfoxide | 1.5565 | 0.4791 | 0.4257 |
| Methylcysteine | 1.1289 | 0.9154 | 0.8490 |
| Methylmalonic acid | 0.5407 | 1.4356 | 1.4711 |
| methylnicotinamide | 1.7063 | 0.1911 | 0.3450 |
| mevalonate | 0.8259 | 1.2260 | 1.1481 |
| myo-inositol | 0.6760 | 1.3726 | 1.2997 |
| N6-Acetyl-L-lysine | 1.3377 | 0.6445 | 0.6711 |
| N-acetyl-aspartylglutamic acid | 1.4047 | 0.6657 | 0.5600 |
| N-acetyl-glucosamine | 1.2871 | 0.6192 | 0.7598 |
| N-acetyl-glucosamine-1-phosphate | 1.5292 | 0.4167 | 0.4979 |
| N-acetyl-glutamate | 0.8391 | 1.2272 | 1.1277 |
| N-acetyl-glutamine | 1.3773 | 0.5974 | 0.6354 |
| N-acetyl-L-alanine | 1.2380 | 0.7704 | 0.7578 |
| N-acetyl-L-aspartic acid | 0.9930 | 1.1266 | 0.9472 |
| N-acetyl-L-ornithine | 0.6025 | 1.5647 | 0.8328 |
| N-Acetylputrescine | 1.1663 | 1.1834 | 0.6589 |
| N-acetyl spermidine | 1.0033 | 0.8416 | 1.0742 |
| N-acetyl spermine | 1.0825 | 0.7767 | 0.9879 |
| NADH | 0.6427 | 1.3088 | 1.3815 |
| NADH-nega | 0.7341 | 1.1852 | 1.3062 |
| NAD+_nega | 0.8779 | 0.8901 | 1.2381 |
| NADPH | 0.4076 | 2.6660 | 1.0556 |
| NADPH-nega | 0.9595 | 1.4999 | 0.8108 |
| NADP+_nega | 1.1168 | 0.8747 | 0.8875 |
| NAD+_posi | 0.9279 | 1.0912 | 1.0625 |
| NADP+_posi | 0.9932 | 0.9308 | 1.0449 |
| N-carbamoyl-L-aspartate | 1.4583 | 0.4958 | 0.5646 |
| N-carbamoyl-L-aspartate-nega | 0.5494 | 1.4035 | 1.4741 |
| Ng,NG-dimethyl-L-arginine | 1.0208 | 0.9483 | 0.9947 |
| nicotinamide | 0.0208 | 2.1095 | 1.9141 |
| Nicotinamide Riboside | 1.4526 | 0.3568 | 0.6427 |
| Nicotinamide ribotide | 0.9577 | 0.8778 | 1.1246 |
| nicotinate | 1.1716 | NA | 0.9142 |
| O8P-O1P | 1.2965 | 0.7966 | 0.6570 |
| O-acetyl-L-serine | 1.0228 | 0.3923 | 1.2697 |
| OBP | 1.2950 | 0.6887 | 0.7131 |
| ornithine | 1.5033 | 0.4526 | 0.5187 |
| orotate | 0.6156 | 1.3620 | 1.3956 |
| orotidine-5-phosphate | 1.0949 | 0.7357 | 0.9898 |
| oxaloacetate | 0.9458 | 1.0538 | 1.0545 |
| p-aminobenzoate | 0.9588 | 1.0162 | 1.0537 |
| pantothenate | 1.5312 | 0.5404 | 0.4330 |
| phenylalanine | 1.2093 | 0.8399 | 0.7660 |
| Phenyllactic acid | 1.1673 | 0.8327 | 0.8327 |
| Phenylpropiolic acid | 0.7076 | 1.1830 | 1.3471 |
| phenylpyruvate | NA | NA | NA |
| phosphocreatine | 0.8328 | 1.2077 | 1.1469 |
| phosphoenolpyruvate | 0.8946 | 1.2320 | 1.0421 |
| Phosphorylcholine | 0.2572 | 3.0910 | 1.0688 |
| p-hydroxybenzoate | 0.8674 | 1.1981 | 1.0999 |
| prephenate | NA | NA | NA |
| proline | 1.0320 | 0.9332 | 0.9854 |
| propionyl-CoA-posi | 1.0414 | NA | 0.9379 |
| purine | 1.2146 | 0.8129 | 0.7716 |
| putrescine | 0.5612 | 1.7360 | 1.2901 |
| Pyridoxamine | 0.9363 | 0.9352 | 1.1280 |
| pyridoxine | 0.9280 | 0.9963 | 1.1099 |
| Pyroglutamic acid | 0.7836 | 1.3984 | 1.1254 |
| Pyrophosphate | 0.9641 | 1.0012 | 1.0533 |
| pyruvate | 1.0000 | NA | NA |
| quinolinate | 1.1170 | 1.2324 | 0.7082 |
| retinoic acid | 0.6785 | 1.4975 | 1.2335 |
| riboflavin | 0.6957 | 1.1241 | 1.3944 |
| ribose-phosphate | 1.3389 | 0.5791 | 0.7021 |
| S-adenosyl-L-homocysteine-nega | 1.2229 | 0.8454 | 0.7429 |
| S-adenosyl-L-homoCysteine-posi | 1.2286 | 0.8590 | 0.7276 |
| S-adenosyl-L-methioninamine | 1.0000 | NA | NA |
| S-adenosyl-L-methionine | 1.0573 | 0.9813 | 0.9234 |
| sarcosine | 1.3975 | 0.6028 | 0.6024 |
| SBP | 0.7550 | 0.8438 | 1.4457 |
| serine | 1.6281 | 0.3747 | 0.3704 |
| shikimate | NA | NA | 1.0000 |
| shikimate-3-phosphate | 0.8793 | 0.6259 | 1.3681 |
| S-methyl-5-thioadenosine | 0.8344 | 1.0655 | 1.2156 |
| sn-glycerol-3-phosphate | 1.2848 | 0.6462 | 0.7497 |
| sorbitol | 0.6907 | 1.4574 | 1.2353 |
| spermidine | 1.0257 | 0.9043 | 1.0093 |
| spermine | 1.0770 | 0.7354 | 1.0168 |
| S-ribosyl-L-homocysteine-nega | 1.0832 | 0.6139 | 1.0682 |
| S-ribosyl-L-homocysteine-posi | 1.2151 | 0.5161 | 1.0269 |
| succinate | 0.6571 | 1.3668 | 1.3309 |
| succinyl-CoA-posi | 1.0667 | 1.1592 | 0.8204 |
| taurine | 0.4599 | 1.5668 | 1.5268 |
| Taurodeoxycholic acid | 1.0577 | 0.8654 | 1.0096 |
| thiamine | 1.0439 | 0.0020 | 1.4331 |
| thiamine-phosphate | 1.5917 | 0.3429 | 0.4410 |
| Thiamine pyrophosphate | 1.6813 | 0.2904 | 0.3328 |
| threonine | 1.3631 | 0.6570 | 0.6268 |
| thymidine | 1.0000 | NA | NA |
| thymine | 1.2903 | 0.7281 | 0.7006 |
| trans, trans-farnesyl diphosphate | 0.7279 | 0.7949 | 1.3746 |
| trehalose-6-Phosphate | 0.7405 | 1.5581 | 1.1101 |
| trehalose-sucrose | 0.7602 | 1.4812 | 1.1192 |
| tryptophan | 1.0946 | 0.9983 | 0.8590 |
| tyrosine | 1.1114 | 0.9611 | 0.8524 |
| UDP-D-glucose | 0.9276 | 1.0567 | 1.0802 |
| UDP-D-glucuronate | 1.3639 | 0.6425 | 0.6329 |
| UDP-N-acetyl-glucosamine | 1.4781 | 0.4460 | 0.5598 |
| UDP-nega | 1.5087 | 0.4934 | 0.4903 |
| UMP | 1.4207 | 0.7984 | 0.4697 |
| uracil | 0.9970 | 0.8839 | 1.0626 |
| Urea | 0.9390 | 1.1521 | 1.0155 |
| Uric acid | 1.7065 | 0.2631 | 0.3088 |
| uridine | 1.6665 | 0.2840 | 0.3583 |
| UTP-nega | 0.9440 | 1.2335 | 0.9673 |
| valine | 1.1408 | 0.9086 | 0.8346 |
| xanthine | 0.7308 | 1.2413 | 1.2831 |
| xanthosine | 1.7277 | 0.1918 | 0.3126 |
| xanthosine-5-phosphate | 0.6729 | 1.4947 | 1.2432 |
| Xanthurenic acid | 1.0918 | 0.9971 | 0.8638 |
Factors:
| F1 | Sample source:pancreatic cancer cells,PANC1 | Treatment:CLSA25 |
| F2 | Sample source:pancreatic cancer cells, PANC1 | Treatment:Control |
| F3 | Sample source:pancreatic cancer cells,PANC1 | Treatment:Control |
