Data for (Study ST003725)

(Analysis AN006111)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4
1,2^-O-dimethyladenosine 0.9588 0.9709 1.0365 1.0337
1-methyladenosine 1.0093 1.0771 0.9605 0.9530
1-methylguanosine 1.0261 1.0461 0.9497 0.9782
1-methylinosine 1.0180 1.0620 0.9850 0.9350
1-methylpseudouridine_1 0.9906 1.0256 1.0964 0.8874
1-methylpseudouridine_2 1.0235 1.0172 1.0699 0.8908
2,8-dimethyladenosine 0.9023 0.9175 1.2110 0.9685
2-methyladenosine 0.9354 0.9097 1.0425 1.1134
2-methylthio-N6-isopentenyladenosine_1 1.1316 0.9043 1.0719 0.8923
2-methylthio-N6-isopentenyladenosine_2 0.8453 1.1773 0.9279 1.0495
2-methylthio-N6-methyladenosine 0.6889 1.2221 1.0476 1.0423
2^-O-methyladenosine 0.9989 0.9868 0.9880 1.0263
2^-O-methylcytidine 0.9724 1.0403 1.0230 0.9643
2^-O-methylguanosine 0.7959 0.9343 1.1727 1.0971
2^-O-methylinosine_1 1.0276 0.8567 1.0332 1.0860
2^-O-methylinosine_2 0.9215 1.1258 0.8856 1.0697
2^-O-methyluridine 0.7786 0.8830 1.1684 1.1700
2-thio-2^-O-methyluridine 1.2062 0.7792 0.9873 1.0274
2-thiocytidine 0.9948 1.1011 0.9602 0.9439
2-thiouridine 0.9894 1.0795 0.9665 0.9654
3,2^-O-dimethyluridine 0.9745 0.9860 0.9859 1.0537
3-(3-amino-3-carboxypropyl)uridine 1.0532 1.0373 0.9901 0.9193
3-methylcytidine 0.8470 0.7585 0.7734 1.6211
3-methylpseudouridine_1 1.0203 1.0822 1.0359 0.8627
3-methylpseudouridine_2 1.0514 1.0209 1.0080 0.9197
3-methyluridine 1.0496 1.0028 1.0432 0.9044
4-demethylwyosine 1.0773 0.9588 0.9517 1.0125
4-thiouridine 0.9979 1.0749 0.9792 0.9479
5,2^-O-dimethylcytidine 0.2974 0.3269 0.7993 2.5764
5,2^-O-dimethyluridine 0.8506 1.1964 0.8606 1.0923
5-carbamoylmethyluridine_1 1.0994 0.9133 0.8606 1.1268
5-carbamoylmethyluridine_2 0.9031 1.0185 1.0085 1.0718
5-carboxycytidine 0.9987 1.0353 0.9569 1.0095
5-carboxymethylaminomethyluridine_1 0.8790 0.9275 1.2193 0.9743
5-carboxymethylaminomethyluridine_2 1.0531 1.0420 0.9784 0.9266
5-carboxymethylaminomethyluridine_3 0.9522 0.9944 0.9543 1.0991
5-carboxymethyluridine_1 1.0447 0.9539 1.0640 0.9396
5-carboxymethyluridine_2 1.1062 0.8959 1.2321 0.7658
5-formylcytidine 0.9464 1.0585 1.1584 0.8367
5-hydroxymethylcytidine 1.0609 0.8936 1.0147 1.0319
5-hydroxyuridine 1.2049 0.9162 1.1261 0.7520
5-methoxycarbonylmethyl-2^-O-methyluridine 0.9101 0.7927 1.1565 1.1406
5-methoxycarbonylmethyl-2-thiouridine_1 0.8821 1.1241 0.9488 1.0450
5-methoxycarbonylmethyl-2-thiouridine_2 0.9720 1.0089 1.0875 0.9316
5-methoxycarbonylmethyluridine_1 0.9269 0.9458 1.2119 0.9154
5-methoxycarbonylmethyluridine_2 1.0373 0.8571 1.1364 0.9707
5-methoxyuridine 1.1512 0.8271 1.0032 1.0149
5-methyl-2-thiouridine 0.8931 1.0822 1.0302 0.9945
5-methylaminomethyl-2-thiouridine_1 0.8829 1.1159 0.9723 1.0289
5-methylaminomethyl-2-thiouridine_2 0.9828 0.9969 1.0654 0.9548
5-methylcytidine 0.9369 1.0318 1.0422 0.9891
5-methyldihydrouridine 0.9824 1.1130 0.9613 0.9437
5-methyluridine 2.2927 0.7451 0.4892 0.4730
7-methylguanosine 1.0080 0.9606 0.9835 1.0489
8-methyladenosine 0.7724 0.8519 1.1036 1.2722
adenosine 1.0196 1.0041 1.0063 0.9700
cytidine 1.0340 1.0292 0.9953 0.9414
dihydrouridine 0.8774 1.0013 1.0157 1.1056
guanosine 1.0343 1.0173 1.0066 0.9418
inosine 0.5713 0.7850 1.8347 0.8089
isowyosine 0.8891 1.3216 0.7460 1.0447
N2,2^-O-dimethylguanosine 0.8744 1.0471 1.0635 1.0150
N2,7-dimethylguanosine_1 1.0407 1.0242 0.9848 0.9508
N2-methylguanosine 1.1594 1.1106 0.9458 0.7831
N2,N2,7-trimethylguanosine_1 0.9446 0.9966 1.0812 0.9776
N2,N2-dimethylguanosine 1.1198 1.1332 0.9653 0.7816
N4,2^-O-dimethylcytidine 0.2856 0.3145 0.8078 2.5921
N4-acetyl-2^-O-methylcytidine_1 0.3525 0.6380 1.4535 1.5560
N4-acetyl-2^-O-methylcytidine_2 0.3894 0.6862 1.4238 1.5006
N4-acetylcytidine_1 0.1677 0.2360 1.3747 2.2217
N4-acetylcytidine_2 0.1684 0.2369 1.3736 2.2212
N4-methylcytidine_1 0.9376 1.0327 1.0412 0.9886
N4-methylcytidine_2 0.8747 0.9271 1.2095 0.9885
N4,N4,2^-O-trimethylcytidine 1.0257 0.7544 1.0105 1.2094
N4,N4-dimethylcytidine 1.0370 0.9976 1.0199 0.9456
N6,2^-O-dimethyladenosine 0.9573 0.9648 0.9992 1.0787
N6-acetyladenosine_1 0.6846 0.6507 0.8021 1.8561
N6-acetyladenosine_2 0.9995 0.9589 0.9682 1.0734
N6-(cis-hydroxyisopentenyl)adenosine 0.9061 0.8760 1.0738 1.1441
N6-formyladenosine_1 1.1252 0.9944 0.9109 0.9694
N6-formyladenosine_2 1.0755 1.1281 1.0661 0.7343
N6-hydroxymethyladenosine_1 0.9629 1.0036 0.9278 1.1056
N6-hydroxymethyladenosine_2 0.9609 1.0048 0.9683 1.0659
N6-isopentenyladenosine_1 0.9682 0.9623 1.0030 1.0664
N6-isopentenyladenosine_2 0.9703 0.9800 0.9863 1.0635
N6-methyladenosine 0.7807 0.8458 1.1119 1.2617
N6-methyl-N6-threonylcarbamoyladenosine_1 0.9535 0.9806 0.6040 1.4715
N6-methyl-N6-threonylcarbamoyladenosine_2 0.9113 0.9027 1.0623 1.1237
N6,N6,2^-O-trimethyladenosine 1.0178 1.1357 1.0526 0.7943
N6,N6-dimethyladenosine 1.0800 1.0593 1.0257 0.8349
N6-threonylcarbamoyladenosine_1 0.7323 0.6690 1.1194 1.4792
N6-threonylcarbamoyladenosine_2 0.7436 0.6822 1.0667 1.5023
O6-methylguanine 0.8982 0.8946 1.1413 1.0639
pseudouridine 0.9234 1.0101 1.0517 1.0148
uridine 1.0393 1.0083 1.0049 0.9475
uridine 5-oxyacetic acid methyl ester_1 0.9307 1.0144 1.0497 1.0055
uridine 5-oxyacetic acid methyl ester_2 1.1447 0.9573 0.9681 0.9299
uridine 5-oxyacetic acid methyl ester_3 0.6944 1.0383 1.2300 1.0381
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Factors:

F1Growth temperature:65C
F2Growth temperature:75C
F3Growth temperature:85C
F4Growth temperature:95C
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