Data for (Study ST003741)

(Analysis AN006142)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4F5F6F7F8F9
2-Phosphoglyceric acid 1.1869 1.6194 2.0002 1.7929 0.4364 1.1190 0.3519 0.7163 0.9674
3-Phosphoglyceric acid 1.2351 2.2062 2.0456 2.1155 0.2926 0.8064 0.2305 0.5360 0.8515
4-Hydroxyproline 1.1033 0.8628 1.0043 0.9082 1.2972 1.2192 1.3085 1.2377 1.1290
6-Phosphogluconic acid 1.4295 1.7627 2.4267 1.7909 0.1486 0.8916 0.2864 0.7016 0.8763
Acetylcarnitine* 2.1047 1.9491 1.9384 2.1273 0.2334 0.2548 0.1277 0.2081 1.1214
Adenine 0.8197 0.8635 0.5586 0.9327 1.3621 1.0325 1.8172 1.4157 1.1608
Adenosine 0.1714 0.2189 0.2011 0.1951 1.7727 3.0525 1.8946 1.8700 0.8786
Adenosine diphosphate 1.2868 0.9264 1.9450 0.8571 0.6649 1.1421 0.9873 1.0433 1.1730
Adenosine diphosphate ribose 0.5013 0.3666 0.5615 0.3894 1.9648 1.6749 1.8715 1.6590 1.0930
Adenosine monophosphate 0.7923 0.4989 1.2193 0.4070 1.3929 1.3235 2.6181 1.0599 0.9405
Adenosine triphosphate 1.3182 1.6260 2.1349 1.8029 0.2425 0.8970 0.2674 0.7643 1.0694
Alanine 1.4400 1.1236 1.2827 1.1796 0.9670 0.8264 1.1246 0.9755 1.1373
Arginine 0.8309 0.8104 0.7421 0.8103 1.4302 1.3049 1.6031 1.4295 1.1191
Asparagine 0.8895 0.6196 0.7509 0.7115 1.4803 1.4893 1.6387 1.4725 1.0738
Aspartic acid 1.3126 1.0727 1.2206 1.2145 0.8542 0.9499 1.4038 1.0585 1.0539
Bilirubin 0.0718 0.0064 0.0329 0.0009 6.5672 2.6191 0.0185 0.0009 0.9406
Carnitine 1.9835 1.9083 1.8475 2.0697 0.3297 0.3243 0.3164 0.3398 1.0259
Cholic acid 0.4807 0.4250 0.5946 0.4303 1.5742 1.5648 2.0255 1.7459 1.1610
cis-Aconitic acid 1.1584 0.6090 1.0384 0.9216 1.1969 1.8598 1.0540 1.2388 1.0527
Citrulline 1.4809 1.3008 1.4299 1.4332 0.9267 0.8886 0.6999 0.9150 1.0614
Creatinine 1.7361 1.5062 1.6644 1.5279 0.6853 0.5933 0.7014 0.7081 1.0177
Cytidine diphosphate* 0.0810 0.0973 0.3969 0.1297 1.9231 2.2959 1.9163 2.4422 0.9471
Cytidine monophosphate 0.0200 0.0072 0.0072 0.0072 0.5466 0.5820 6.6692 0.9627 1.1947
Dihydroorotic acid 1.1666 0.7638 1.3848 1.5484 0.1816 0.5641 0.5826 0.8239 2.0880
Fructose* 0.1336 0.0689 0.0904 0.0583 2.4106 1.6853 2.4333 1.6832 1.3165
Fructose 1,6-bisphosphate 1.2747 1.8913 2.2912 2.2290 0.2299 0.7147 0.1831 0.5423 0.9169
Fructose 6-phosphate 1.0276 1.3713 1.2086 1.5809 1.0020 0.9541 0.9028 1.0056 1.0725
Fumaric acid 0.9000 0.7438 0.8683 0.8309 1.0335 1.3466 1.2991 1.9219 1.1106
Gluconic acid 1.7014 1.1239 1.3517 1.5150 0.6935 0.8728 0.8412 0.8382 1.1186
Glucose 2.4693 1.6210 1.7835 1.5792 0.2029 0.7939 0.0222 0.5179 1.1047
Glucose 6-phosphate 0.8027 0.3938 0.8398 0.5867 1.6800 1.7258 1.4050 1.6451 1.0604
Glutamic acid 0.5887 0.4196 0.5407 0.4557 1.7556 1.8922 1.7280 1.8401 0.9896
Glutamine 1.2197 0.8729 1.0299 0.9905 1.2694 1.2963 1.2521 1.1257 1.0717
Glutathione (GSH) 1.1856 0.7399 0.9842 0.8768 1.6956 1.0511 1.5846 1.0666 0.9975
Glutathione (GSSG) 1.4790 1.1627 1.8585 1.4085 0.6636 1.0627 0.6334 0.8119 1.0318
Glyceraldehyde 3-phosphate 0.3262 4.2149 0.5663 2.1854 0.0991 0.1450 0.0341 1.4515 0.8734
Glycerol 3-phosphate 0.6980 0.7543 0.7280 0.7804 1.4911 1.7274 1.0471 1.7562 1.0708
Guanine 0.5308 0.7141 0.4581 0.6231 2.1424 1.3641 2.0292 1.0994 1.0996
Guanosine diphosphate 0.8674 0.7705 1.5178 0.7411 0.8147 1.7273 1.0531 1.4299 1.1131
Guanosine monophosphate 0.1018 0.0536 0.1994 0.0786 1.6795 1.9421 2.6875 2.1266 1.1633
Hexose 6-phosphate 1.5301 1.3302 1.5511 1.4671 0.6696 0.9258 0.7055 0.8913 1.0269
Hypoxanthine 1.1797 1.1021 0.9990 1.0327 1.4650 1.0615 1.2521 0.8795 1.1139
Indoleacrylic acid 1.8837 1.9630 1.9009 1.7733 0.3074 0.4442 0.3505 0.4430 1.0565
Indolepyruvate 2.0953 1.3965 1.8972 1.9016 0.5442 0.3462 0.5067 0.4467 1.0317
Inosine Monophosphate 1.3042 1.0570 1.3387 1.0789 0.8743 1.3302 0.8020 1.2339 1.0453
Inosine triphosphate 1.4888 1.5141 2.5507 1.6506 0.2220 0.8301 0.2429 0.6841 1.0051
Inositol* 0.8032 0.4753 0.5954 0.6627 1.4256 1.7074 1.7499 1.5783 1.0958
Isoleucine 1.1731 1.0093 1.0665 1.0501 1.2556 1.1605 1.1687 1.1011 1.1064
Lactic acid 0.2281 0.1599 0.1907 0.1495 2.2875 1.6411 2.2814 1.6509 1.3049
Leucine 0.9197 0.8055 0.8547 0.8245 1.3077 1.1190 1.7483 1.3988 1.1102
Lysine 0.6782 0.5765 0.6714 0.6041 1.0939 1.0710 2.3257 2.0197 1.0792
Mannose 6-phosphate 0.9251 0.6757 1.0333 0.8374 1.4144 1.3504 1.4046 1.3190 1.0891
Mesaconic acid 0.3105 0.1312 0.2449 0.2450 1.8401 2.3833 2.0582 2.0606 0.9281
Methionine 1.3418 1.2517 1.2575 1.1842 0.8241 1.0235 0.9136 1.1164 1.1006
myo-Inositol 0.8269 0.6201 0.7219 0.6535 1.5695 1.5550 1.5790 1.4507 1.1115
N-Acetylalanine* 0.5811 0.4475 0.4133 0.4310 1.2074 1.3251 1.9663 2.6077 1.0844
N-Acetyl-aspartic acid 0.9994 0.5820 0.6674 0.8441 1.3067 1.2042 2.3474 1.1643 1.0322
N-Acetyl-methionine 0.1443 0.1183 0.1435 0.1603 1.6009 1.8873 2.1256 2.4573 1.2724
N-Acetylserine 0.0155 0.0434 0.0590 0.0483 1.5169 2.1948 2.6463 2.4380 1.1096
NAD 0.2320 0.1909 0.2236 0.2038 2.1479 1.9296 2.0749 1.9667 1.1063
NADP 1.1925 1.4898 1.8923 1.5378 0.4123 1.2470 0.4315 0.9178 1.0377
N-alpha-Acetyl-lysine* 0.9892 0.3979 0.4476 0.5616 1.6401 1.6863 1.9016 1.6339 0.9631
O-Acetylserine 0.1161 0.1129 0.1178 0.1760 1.4630 1.7862 2.6727 2.1089 1.3215
O-Phosphoethanolamine 0.0349 0.0351 0.0343 0.0357 2.4390 1.3763 3.1877 1.8346 1.1108
Ophthalmic acid 2.1368 2.1921 2.0568 2.2556 0.1079 0.1497 0.0981 0.1377 1.0295
Ornithine 1.4870 1.3053 1.4250 1.3986 0.9062 0.9040 0.7300 0.9247 1.0546
Oxoglutaric acid 0.3278 0.2006 0.2551 0.2608 1.8047 2.2645 2.0374 1.8304 1.1022
Pantothenic acid 1.0207 0.8197 0.8640 0.8050 1.2961 1.4273 1.2588 1.3866 1.1272
Phenylalanine 0.8189 0.7037 0.7576 0.7105 1.3141 1.0910 2.0150 1.5660 1.1113
Phosphocreatine 1.9998 1.9628 2.0511 2.0660 0.2186 0.2957 0.2003 0.3235 1.0352
Phosphodimethylethanolamine* 0.1081 0.0826 0.1059 0.0903 3.0054 2.1159 1.8452 1.6337 1.1048
Pipecolic acid 0.0058 0.0034 0.0037 0.0037 0.7153 0.5155 4.4589 3.2225 1.1350
Proline 0.9468 0.8650 0.8664 0.7895 1.2890 1.1419 1.7829 1.3569 1.0792
Pyridoxine 0.9171 1.1729 0.8163 1.1654 1.1944 1.1493 1.1735 1.2814 1.1643
Pyroglutamic acid 1.4669 0.9574 1.0985 0.9765 1.1890 1.0164 1.2384 1.0279 1.1110
Pyruvic acid 0.1136 0.0506 0.1032 0.0565 2.9598 1.5130 2.6452 1.3428 1.2035
Riboflavin* 0.4126 0.4124 0.3697 0.3061 2.1391 1.7786 1.8782 1.6799 1.1056
Ribose 5-phosphate 0.9877 1.5707 1.0000 1.2889 1.0575 0.8770 1.0163 1.2451 1.0735
S-Adenosylhomocysteine* 0.3118 0.2891 0.3551 0.4136 2.0100 1.5013 2.4077 1.7958 1.0510
Sedoheptulose 7-phosphate 0.2266 0.2661 0.2320 0.3033 2.7259 0.4887 3.7887 0.7585 1.1927
Serine 1.0697 0.7261 0.8915 0.8773 1.2643 1.3466 1.5172 1.3333 1.0865
Succinic acid 0.5087 0.3855 0.4058 0.4665 1.1778 1.3076 2.7282 1.7916 1.0288
Sucrose 0.5007 0.7912 0.4656 0.2997 1.3445 1.2410 1.5932 2.2187 1.2895
Taurine 2.2226 1.8539 1.8950 2.0835 0.2008 0.2273 0.2581 0.2528 1.0977
Threonic acid 2.0652 1.8055 1.5966 2.0173 0.3261 0.4089 0.3844 0.3833 1.1022
Threonine 1.0155 0.8215 0.8544 0.8867 1.2223 1.0936 1.7123 1.3712 1.1107
Thymidine 0.0255 0.0301 0.0543 0.0332 2.6445 1.5948 3.1786 1.3187 1.1320
Tryptophan 0.8622 0.8037 0.7690 0.6426 1.2538 1.2042 1.8346 1.5396 1.1125
Tyrosine 1.0379 1.0236 0.9413 0.9656 1.1058 1.0614 1.4061 1.3179 1.1698
Ureidosuccinic acid 1.8302 1.6806 1.8651 1.9140 0.1709 0.6350 0.1973 0.8276 1.0373
Uridine 0.3380 0.1793 0.2907 0.1775 2.2942 1.3531 3.0069 1.2155 1.1656
Uridine 3-monophosphate 0.0063 0.0059 0.0069 0.0053 0.7262 1.1372 5.2597 1.6928 1.1770
Uridine 5-diphosphate 0.0800 0.0309 0.1479 0.0086 2.0267 2.5137 1.9305 2.7127 0.8694
Uridine diphosphategalactose 1.3504 1.2546 1.4460 1.2645 0.8080 1.0776 0.8339 0.9966 1.0448
Uridine diphosphate glucose 1.3472 1.2454 1.4189 1.3178 0.8106 1.0781 0.8462 0.9953 1.0282
Valine 0.9324 0.8080 0.7241 0.6536 1.2526 0.9252 2.0871 1.6377 1.0878
Xylose 5-phosphate 1.0429 1.4171 1.0156 1.2709 1.0968 0.7975 1.0924 1.1768 1.1408
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Factors:

F1Treatment:non-infected Bilirubin | Timepoint:12h | Sample source:Red blood cells
F2Treatment:non-infected Bilirubin | Timepoint:8h | Sample source:Red blood cells
F3Treatment:non-infected DMSO | Timepoint:12h | Sample source:Red blood cells
F4Treatment:non-infected DMSO | Timepoint:8h | Sample source:Red blood cells
F5Treatment:Plasmodium falciparum infected Bilirubin | Timepoint:12h | Sample source:Red blood cells
F6Treatment:Plasmodium falciparum infected Bilirubin | Timepoint:8h | Sample source:Red blood cells
F7Treatment:Plasmodium falciparum infected DMSO | Timepoint:12h | Sample source:Red blood cells
F8Treatment:Plasmodium falciparum infected DMSO | Timepoint:8h | Sample source:Red blood cells
F9Treatment:pooled QC | Timepoint:pooled QC | Sample source:pooled QC
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