Data for (Study ST003794)
(Analysis AN006236)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 1-3-Bisphosphoglycerate | 1.1067 | 0.8252 | 0.9729 | 0.9383 |
| 1-4-beta-D-Xylan | 0.9466 | 0.9501 | 1.2014 | 1.0672 |
| 2/3-Phospho-D-glycerate | 1.4026 | 0.5767 | 0.6384 | 0.5778 |
| 2-Aminomuconate | 0.9335 | 1.0310 | 1.1401 | 1.0255 |
| 2-Hydroxyglutarate/Citramalate | 1.0297 | 1.0919 | 0.9075 | 0.7313 |
| 2-Oxoglutarate | 0.8137 | 0.8298 | 1.6122 | 1.4040 |
| 3^,5^-Cyclic IMP | 1.1017 | 0.7832 | 0.9926 | 1.0552 |
| 3-Methyl-2-Oxobutanoate (ketoacid of Val) | 0.4290 | 1.6884 | 1.4994 | 1.3623 |
| 3-Methyleneoxindole | 1.0684 | 0.7809 | 1.1264 | 0.9940 |
| 3-Sulfocatechol | 1.3775 | 0.7307 | 0.5341 | 0.4751 |
| 4-Methyl-2-Oxpentanoate/(S)-3-Methyl-2-Oxopentanoic Acid (ketoacids of Ile and Leu) | 0.2732 | 1.7430 | 1.7400 | 1.6515 |
| 4-Pyridoxate | 0.1192 | 0.2772 | 3.5249 | 3.4033 |
| 5-Hydroxyindoleacetate | 0.5982 | 1.7822 | 1.0304 | 1.0033 |
| 5-Oxoproline | 0.8483 | 1.1899 | 1.0901 | 1.1603 |
| 5^-Phosphoribosyl-N-formylglycinamide | 1.0285 | 0.4899 | 1.2967 | 1.2561 |
| 6-Phospho-D-gluconate | 0.8948 | 1.2765 | 0.9454 | 0.9106 |
| (8Z-11Z-14Z)-Icosatrienoic acid | 1.0422 | 1.2187 | 0.7137 | 0.6630 |
| ADP | 1.0192 | 0.8320 | 1.1110 | 1.1668 |
| a-Linolenic acid (Octadecatrienoic acid) | 1.2337 | 1.0016 | 0.5373 | 0.5181 |
| alpha-D-Ribose 1-phosphate | 0.6552 | 1.5491 | 1.1840 | 1.0534 |
| ATP | 1.2829 | 0.7003 | 0.7313 | 0.7392 |
| CDP | 1.3595 | 0.4927 | 0.6378 | 1.0896 |
| Citrate | 1.5398 | 0.3915 | 0.5324 | 0.5220 |
| Cytidine | 1.6236 | 0.3519 | 0.4180 | 0.3664 |
| dAMP | 1.1621 | 1.0038 | 0.7689 | 0.4782 |
| D-Arabitol | 1.1399 | 0.9173 | 0.7962 | 0.8161 |
| D-Erythrose 4-phosphate | 0.9586 | 1.3566 | 0.6807 | 0.8168 |
| D-Fructose 1-6-bisphosphate | 0.8005 | 1.2684 | 1.1480 | 1.0959 |
| D-Glucose | 1.0036 | 0.9200 | 1.0916 | 1.0352 |
| D-Glucose 6-phosphate | 0.7334 | 1.4626 | 1.0464 | 1.1192 |
| D-Glyceraldehyde 3-phosphate/Glycerone phosphate | 0.6854 | 1.2405 | 1.3653 | 1.4352 |
| Diphosphate | 0.8873 | 1.3818 | 0.8658 | 0.7990 |
| D-Rhamnose | 1.1528 | 0.9732 | 0.7345 | 0.6944 |
| D-Ribose | 1.0545 | 0.8939 | 0.9620 | 1.0673 |
| Ethanolamine phosphate | 0.8851 | 1.0669 | 1.1781 | 1.1326 |
| Fumarate | 0.9703 | 0.9973 | 1.1125 | 0.9612 |
| GDP | 0.8342 | 1.5872 | 0.7213 | 0.7908 |
| Glycerol 3-phosphate | 0.9859 | 1.1035 | 0.9075 | 0.9591 |
| glycine | 0.8310 | 1.2167 | 1.0523 | 1.2594 |
| GTP | 1.5226 | 0.4216 | 0.3881 | 0.2453 |
| Hemine | 1.0612 | 0.8870 | 1.0653 | 0.8412 |
| Heptanoic acid | 1.1183 | 0.8964 | 0.9617 | 0.6773 |
| Hexadecanoic acid (palmitic acid) | 1.1090 | 0.9425 | 0.8513 | 0.8157 |
| IDP | 1.0666 | 0.9602 | 0.8197 | 1.0804 |
| IMP | 0.8264 | 1.1797 | 1.1898 | 1.1228 |
| Indole-3-acetate | 1.0889 | 0.9247 | 0.8970 | 0.8987 |
| Lactate | 1.0100 | 1.0270 | 0.9715 | 0.9160 |
| L-cystine | 1.2821 | 0.5873 | 0.8456 | 0.8542 |
| Linoleic acid ((9Z,12Z)-Octadecadienoic acid) | 1.2017 | 1.0714 | 0.5353 | 0.5049 |
| Malate | 0.9879 | 0.9734 | 1.0965 | 0.9598 |
| Maltose | 0.9168 | 0.9319 | 1.2098 | 1.2838 |
| Maltotriose | 0.9969 | 0.8228 | 1.1558 | 1.2387 |
| Mannitol | 0.8163 | 1.4105 | 0.9541 | 0.9624 |
| N-Acetylneuraminate | 0.8042 | 1.1186 | 1.3256 | 1.1680 |
| N-Acetylornithine | 1.0821 | 1.0024 | 0.8683 | 0.7638 |
| NADP+ | 0.9319 | 1.1195 | 1.0507 | 0.9487 |
| Nicotinate ribonucleotide | 1.4164 | 0.5078 | 0.6539 | 0.6705 |
| Nonanoic acid (pelargonate) | 1.0216 | 0.8960 | 1.1097 | 0.9631 |
| N-Succinyl-L-glutamate 5-semialdehyde | 1.0239 | 0.9978 | 0.9738 | 0.9152 |
| Octadecenoic acid (Oleic acid) | 1.2555 | 0.9848 | 0.5036 | 0.5057 |
| Octanoic acid (caprylate) | 1.0891 | 0.7467 | 1.0897 | 1.0459 |
| Phosphate | 0.8889 | 1.1304 | 1.1166 | 1.0421 |
| Phosphoenolpyruvate | 1.1273 | 0.8199 | 0.9336 | 0.9095 |
| Pyridoxal | 0.1757 | 0.3629 | 3.1575 | 3.5420 |
| Pyridoxamine 5^-phosphate | 1.0085 | 1.4256 | 0.5090 | 0.6544 |
| Pyruvate | 0.6762 | 1.5965 | 1.0630 | 1.0277 |
| Quinolinic Acid | 0.9646 | 1.2639 | 0.9384 | 0.5442 |
| Sedoheptulose 1-phosphate | 0.7579 | 1.5032 | 1.0231 | 0.8970 |
| Sphingosine 1-phosphate | 0.7099 | 1.0291 | 1.6292 | 1.3950 |
| Succinate | 1.0905 | 0.9135 | 0.9504 | 0.8159 |
| Tetradecenoic acid (myristoleic acid) | 1.5408 | 0.5959 | 0.3345 | 0.2989 |
| trans-4-Hydroxy-L-proline | 0.9633 | 1.0607 | 0.9772 | 1.0839 |
| UDP | 1.1516 | 0.6139 | 1.0893 | 1.0699 |
| UDP-glucose | 0.8741 | 1.2657 | 1.0126 | 0.9333 |
| UDP-N-acetyl-D-glucosamine | 0.7779 | 1.7021 | 0.6169 | 0.9923 |
| Urate | 0.8896 | 1.1956 | 1.0214 | 1.0327 |
| UTP | 1.1216 | 1.0630 | 0.7131 | 0.7178 |
Factors:
| F1 | Disease state:Healthy control |
| F2 | Disease state:MSUD |
| F3 | Disease state:MSUD with transplant |
| F4 | Disease state:Pool of MSUD with transplant |
