Data for (Study ST003982)
(Analysis AN006558)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Citric acid_C13-label-1 | 3.3730 | 0.4238 | 0.7806 | 0.3721 | 0.4615 | 0.2428 | 0.3111 | 0.1800 | 0.9550 | 0.3822 | 0.9012 | 0.4871 |
| Citric acid_C13-label-2 | 3.5743 | 0.2362 | 0.5185 | 0.1043 | 0.6093 | 0.2623 | 0.1850 | 0.1382 | 1.1315 | 0.1807 | 0.9645 | 0.1622 |
| Citric acid_C13-label-3 | 3.8019 | 0.2791 | 0.3811 | 0.1217 | 0.7579 | 0.3699 | 0.1791 | 0.1905 | 1.0431 | 0.1999 | 0.7701 | 0.1733 |
| Citric acid_C13-label-4 | 3.5099 | 0.1443 | 0.2819 | 0.0569 | 1.1008 | 0.2780 | 0.1882 | 0.0995 | 1.0771 | 0.1295 | 0.8774 | 0.1163 |
| Citric acid_C13-label-5 | 1.8158 | NA | 0.3517 | NA | 1.0992 | 0.3227 | 0.2000 | NA | 1.0100 | NA | 1.4529 | NA |
| Citric acid_C13-label-6 | 1.1207 | NA | NA | NA | 1.5105 | NA | NA | NA | 0.5520 | NA | 0.9084 | NA |
| Citric acid_PARENT | 2.2248 | 0.7232 | 1.1177 | 0.8830 | 0.4695 | 0.3424 | 0.5781 | 0.3508 | 0.8222 | 0.8950 | 1.1062 | 1.2133 |
| Fumaric acid_C13-label-1 | 1.5807 | 1.5424 | 1.8241 | 1.4914 | NA | NA | NA | NA | 0.2269 | 0.2193 | 0.3075 | 0.3582 |
| Fumaric acid_C13-label-2 | 0.8976 | 0.0841 | 1.4529 | 0.1635 | NA | NA | NA | NA | NA | NA | NA | NA |
| Fumaric acid_C13-label-3 | 0.8216 | NA | 1.1784 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Fumaric acid_C13-label-4 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Fumaric acid_PARENT | 1.7691 | 2.1541 | 1.6179 | 2.0090 | NA | NA | 0.0033 | NA | 0.2362 | 0.1581 | 0.3036 | 0.3453 |
| L-Alanine_C13-label-1 | 2.4564 | 0.8841 | 1.6004 | 1.1382 | 0.0207 | 0.0035 | 0.0066 | 0.0056 | 1.2677 | 0.8783 | 1.0505 | 1.0787 |
| L-Alanine_C13-label-2 | 3.5095 | 0.0212 | 1.7287 | 0.1333 | 0.0322 | NA | 0.0077 | NA | 0.8269 | 0.0192 | 0.6495 | 0.0538 |
| L-Alanine_C13-label-3 | 2.9260 | NA | 1.3435 | NA | 0.0339 | NA | 0.0094 | NA | 0.9843 | NA | 0.7029 | NA |
| L-Alanine_PARENT | 1.3627 | 1.5243 | 1.4327 | 1.8492 | 0.0124 | 0.0062 | 0.0060 | 0.0097 | 1.5926 | 1.5493 | 1.4360 | 1.8492 |
| L-Asparagine_C13-label-1 | 1.4735 | 1.2523 | 1.7126 | 1.4800 | 0.0734 | 0.1260 | 0.1002 | 0.1887 | 1.7939 | 2.1469 | 0.7262 | 1.4069 |
| L-Asparagine_C13-label-2 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| L-Asparagine_C13-label-3 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| L-Asparagine_C13-label-4 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| L-Asparagine_PARENT | 1.5084 | 1.3620 | 1.7442 | 1.5423 | 0.0694 | 0.1107 | 0.0933 | 0.1614 | 1.7148 | 2.0499 | 0.7284 | 1.4812 |
| L-Aspartic acid_C13-label-1 | 3.5419 | 1.9353 | 2.2588 | 0.7025 | 0.2588 | 0.0237 | 0.0464 | 0.0298 | 0.3118 | 0.4010 | 0.1351 | 0.1438 |
| L-Aspartic acid_C13-label-2 | 4.0577 | 0.0832 | 1.4936 | 0.0587 | 0.3102 | NA | 0.0234 | NA | 0.3299 | NA | 0.1567 | NA |
| L-Aspartic acid_C13-label-3 | 3.7453 | NA | 1.6157 | NA | 0.3144 | NA | 0.0221 | NA | 0.2282 | NA | 0.0744 | NA |
| L-Aspartic acid_C13-label-4 | 2.0313 | NA | 0.5447 | NA | 0.2800 | NA | NA | NA | NA | NA | NA | NA |
| L-Aspartic acid_PARENT | 2.0828 | 4.7070 | 2.8801 | 1.7275 | 0.2574 | 0.0602 | 0.0711 | 0.0839 | 0.2101 | 1.0141 | 0.1106 | 0.3469 |
| L-Glutamic acid_C13-label-1 | 3.5642 | 2.0044 | 1.9873 | 0.8164 | 0.0916 | 0.0180 | 0.0298 | 0.0112 | 0.5725 | 0.1950 | 0.3116 | 0.1695 |
| L-Glutamic acid_C13-label-2 | 4.3528 | 0.0539 | 1.3521 | 0.0719 | 0.1237 | NA | 0.0207 | 0.0002 | 0.7700 | 0.0074 | 0.3508 | 0.0162 |
| L-Glutamic acid_C13-label-3 | 3.8994 | NA | 1.1262 | NA | 0.1054 | NA | 0.0134 | NA | 0.6572 | NA | 0.1984 | NA |
| L-Glutamic acid_C13-label-4 | 2.9988 | NA | 1.4154 | NA | 0.1438 | NA | 0.0143 | NA | 0.9805 | NA | 0.2502 | NA |
| L-Glutamic acid_C13-label-5 | 1.6672 | NA | 1.5059 | NA | NA | NA | NA | NA | 0.6456 | NA | 0.1813 | NA |
| L-Glutamic acid_PARENT | 2.3517 | 4.8629 | 2.5651 | 1.8753 | 0.0788 | 0.0481 | 0.0440 | 0.0274 | 0.3521 | 0.4888 | 0.2700 | 0.3890 |
| L-Glutamine_C13-label-1 | 2.3709 | 1.5555 | 1.9378 | 1.5829 | 0.0668 | 0.0414 | 0.0608 | 0.0441 | 1.2046 | 0.6688 | 0.6606 | 0.5996 |
| L-Glutamine_C13-label-2 | 2.8753 | 0.0386 | 1.3545 | 0.1489 | 0.0903 | NA | 0.0492 | 0.0040 | 1.9149 | 0.0150 | 0.6600 | 0.0725 |
| L-Glutamine_C13-label-3 | 2.4819 | NA | 1.0418 | 0.0440 | 0.0832 | NA | 0.0429 | NA | 2.0858 | NA | 0.6509 | 0.0232 |
| L-Glutamine_C13-label-4 | 1.4071 | NA | 1.0188 | NA | 0.0783 | NA | 0.0532 | NA | 2.5776 | NA | 0.8650 | NA |
| L-Glutamine_C13-label-5 | 0.7437 | NA | 0.8403 | NA | NA | NA | NA | NA | 1.7231 | NA | 0.6929 | NA |
| L-Glutamine_PARENT | 1.4905 | 3.3672 | 2.2201 | 3.1774 | 0.0445 | 0.0941 | 0.0617 | 0.0916 | 0.9055 | 1.4443 | 0.6084 | 1.1719 |
| L-Lactic acid_C13-label-1 | 1.9669 | 0.5089 | 1.0848 | 0.7593 | 0.3343 | 0.0569 | 0.2040 | 0.0893 | 1.3304 | 0.7876 | 1.6220 | 1.0864 |
| L-Lactic acid_C13-label-2 | 2.2142 | 0.0114 | 0.9415 | 0.0761 | 0.4298 | NA | 0.2329 | 0.0088 | 1.1959 | NA | 1.7530 | 0.0674 |
| L-Lactic acid_C13-label-3 | 1.5042 | NA | 0.7021 | 0.0226 | 0.3749 | NA | 0.2192 | 0.0026 | 1.5973 | NA | 2.1934 | 0.0194 |
| L-Lactic acid_PARENT | 0.9914 | 1.0882 | 1.0954 | 1.5144 | 0.1690 | 0.1233 | 0.1753 | 0.1799 | 1.4509 | 1.6806 | 1.9496 | 2.2549 |
| L-Malic acid_C13-label-1 | 2.4864 | 0.4566 | 0.9110 | 0.2249 | NA | NA | NA | NA | 0.5636 | 0.4605 | 0.5678 | 0.2143 |
| L-Malic acid_C13-label-2 | 2.7758 | 0.0105 | 0.7210 | 0.0128 | NA | NA | NA | NA | 0.6537 | 0.0358 | 0.6322 | 0.0276 |
| L-Malic acid_C13-label-3 | 2.4535 | NA | 0.6135 | NA | NA | NA | NA | NA | 0.5588 | NA | 0.3742 | NA |
| L-Malic acid_C13-label-4 | 2.5293 | NA | 0.4784 | NA | NA | NA | NA | NA | 0.6475 | NA | 0.3448 | NA |
| L-Malic acid_PARENT | 1.5466 | 1.7939 | 1.2542 | 0.8123 | NA | NA | NA | NA | 0.3675 | 1.7104 | 0.6253 | 0.7153 |
| Oxalacetic acid_C13-label-1 | 1.2387 | NA | NA | NA | NA | NA | NA | NA | NA | NA | 0.0452 | NA |
| Oxalacetic acid_C13-label-2 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Oxalacetic acid_C13-label-3 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Oxalacetic acid_C13-label-4 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Oxalacetic acid_PARENT | 2.4243 | 0.3797 | 0.9569 | 0.5936 | NA | NA | NA | NA | 0.2920 | 0.3934 | 0.5288 | 0.4442 |
| Oxoglutaric acid_C13-label-1 | NA | NA | NA | NA | 1.1858 | 0.2577 | 1.0266 | 0.3796 | 1.5764 | 0.1864 | 0.4107 | NA |
| Oxoglutaric acid_C13-label-2 | NA | NA | NA | NA | 1.2287 | NA | 0.5866 | NA | 1.6085 | NA | 0.2937 | NA |
| Oxoglutaric acid_C13-label-3 | NA | NA | NA | NA | 1.1836 | NA | 0.4641 | NA | 1.4632 | NA | 0.4457 | NA |
| Oxoglutaric acid_C13-label-4 | NA | NA | NA | NA | 1.1738 | NA | 0.4448 | NA | 1.4665 | NA | 0.5747 | NA |
| Oxoglutaric acid_C13-label-5 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Oxoglutaric acid_PARENT | NA | NA | NA | NA | 0.9855 | 0.7457 | 1.3466 | 0.9463 | 0.9010 | 0.4840 | 0.6585 | NA |
| Pyruvic acid_C13-label-1 | 1.0253 | 0.2942 | 0.4316 | 0.3815 | 0.1292 | 0.0293 | 0.1394 | 0.0934 | 1.4862 | 0.4251 | 3.4459 | 1.4880 |
| Pyruvic acid_C13-label-2 | 0.8898 | NA | 0.2696 | 0.0137 | 0.1779 | 0.0001 | 0.1660 | 0.0087 | 1.3718 | NA | 3.9020 | 0.0913 |
| Pyruvic acid_C13-label-3 | 0.4558 | NA | 0.1228 | NA | 0.1415 | NA | 0.1316 | NA | 1.4441 | NA | 3.8989 | 0.0264 |
| Pyruvic acid_PARENT | 0.6846 | 0.6461 | 0.5239 | 0.7646 | 0.0611 | 0.0625 | 0.1016 | 0.1688 | 1.3895 | 0.8266 | 3.4194 | 2.6313 |
| Succinic acid_C13-label-1 | 4.3103 | 0.6727 | 1.5640 | 0.5263 | 0.2437 | 0.0099 | 0.0438 | 0.0104 | 0.3402 | 0.0886 | 0.4080 | 0.1419 |
| Succinic acid_C13-label-2 | 3.9709 | NA | 1.0184 | NA | 0.3097 | NA | 0.0258 | NA | 0.3095 | NA | 0.3656 | NA |
| Succinic acid_C13-label-3 | 3.9927 | NA | 1.1526 | NA | 0.2579 | NA | 0.0128 | NA | 0.3293 | NA | 0.2546 | NA |
| Succinic acid_C13-label-4 | 3.8832 | NA | 0.6737 | NA | 0.4288 | NA | 0.0235 | NA | 0.2707 | NA | 0.1342 | NA |
| Succinic acid_PARENT | 2.9167 | 2.7790 | 2.1374 | 1.9626 | 0.2135 | 0.0407 | 0.0908 | 0.0400 | 0.2339 | 0.3810 | 0.4594 | 0.5379 |
Factors:
| F1 | Sample source:Liver | Treatment condition:CLP | Tracer condition:13C pyruvate |
| F2 | Sample source:Liver | Treatment condition:CLP | Tracer condition:PBS |
| F3 | Sample source:Liver | Treatment condition:Sham | Tracer condition:13C pyruvate |
| F4 | Sample source:Liver | Treatment condition:Sham | Tracer condition:PBS |
| F5 | Sample source:Plasma | Treatment condition:CLP | Tracer condition:13C pyruvate |
| F6 | Sample source:Plasma | Treatment condition:CLP | Tracer condition:PBS |
| F7 | Sample source:Plasma | Treatment condition:Sham | Tracer condition:13C pyruvate |
| F8 | Sample source:Plasma | Treatment condition:Sham | Tracer condition:PBS |
| F9 | Sample source:Skeletal muscle | Treatment condition:CLP | Tracer condition:13C pyruvate |
| F10 | Sample source:Skeletal muscle | Treatment condition:CLP | Tracer condition:PBS |
| F11 | Sample source:Skeletal muscle | Treatment condition:Sham | Tracer condition:13C pyruvate |
| F12 | Sample source:Skeletal muscle | Treatment condition:Sham | Tracer condition:PBS |
