Data for (Study ST004093)
(Analysis AN006785)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 |
|---|---|---|---|---|---|---|
| 2-Aminobutyric acid | 1.0836 | 1.1073 | 1.0483 | 1.0971 | 0.7714 | 0.9408 |
| 2-Hydroxycaproic and or 2-Hydroxyisocaproic acid | 0.7264 | 1.0626 | 0.9428 | 1.0112 | 1.1528 | 1.0888 |
| 2-Hydroxyglutaric acid | 0.9417 | 1.1114 | 1.0208 | 1.0188 | 0.9561 | 0.9644 |
| 2-Hydroxyvaleric and or 2-Hydroxyisovaleric acid | 0.8379 | 1.2447 | 0.9907 | 1.0320 | 0.7802 | 1.1221 |
| 2-Phosphoglyceric acid | 0.7256 | 1.4635 | 1.0099 | 0.9034 | 0.6408 | 1.1082 |
| 3-Phosphoglyceric acid | 0.8374 | 1.3513 | 1.0586 | 1.0071 | 0.6838 | 1.0837 |
| Adenine | 0.4813 | 1.6172 | 0.9937 | 1.0193 | 0.5892 | 1.3037 |
| Adenylsuccinic acid | 0.8516 | 1.1124 | 1.0452 | 1.0975 | 0.7498 | 1.1911 |
| Adipic and or Methylglutaric acid | 0.8683 | 0.9335 | 1.1021 | 1.1012 | 0.9254 | 1.1373 |
| ADP | 0.5241 | 1.4752 | 1.0722 | 1.0428 | 0.5629 | 1.3612 |
| Aminoadipic acid | 0.5832 | 1.1861 | 0.9427 | 0.7045 | NA | 1.1880 |
| AMP | 1.0311 | 1.0107 | 1.0478 | 1.0292 | 0.9510 | 0.9559 |
| Aspartic acid | 1.0048 | 1.1010 | 1.0885 | 1.0626 | 0.8566 | 0.9368 |
| ATP | 0.1938 | 1.8364 | 1.0706 | 1.0809 | 0.2896 | 1.5793 |
| CDP | 0.9555 | 1.0910 | 1.0560 | 1.0266 | 1.0083 | 0.8902 |
| cis-Aconitic acid | 0.9529 | 0.9454 | 1.1023 | 1.0053 | 1.1781 | 0.8518 |
| Citric and or Isocitric acid | 0.9429 | 1.0243 | 1.0641 | 1.0171 | 1.1037 | 0.8749 |
| CMP | 1.4732 | 0.8213 | 1.0403 | 1.0271 | 1.0066 | 0.6539 |
| Cytidine | 1.9739 | 0.3908 | 0.9631 | 1.0074 | 1.4143 | 0.2407 |
| Dihexose | 0.5527 | 0.9176 | 1.2525 | 1.1565 | 0.9929 | 1.1313 |
| dTMP | 1.4315 | 1.1524 | 0.9976 | 1.1592 | 0.4952 | 0.8163 |
| Erythronic and or Threonic acid | 1.1897 | 0.8373 | 1.0674 | 1.0143 | 1.1289 | 0.7896 |
| Fumaric and or Maleic acid | 0.8316 | 1.3288 | 1.0683 | 1.0430 | 0.6208 | 1.1446 |
| GDP | 0.9053 | 1.0658 | 1.0361 | 1.0439 | 0.9117 | 1.0639 |
| Glucosan | 0.9922 | 1.0655 | 1.0422 | 1.0420 | 0.9267 | 0.9595 |
| Glutamic acid | 1.2816 | 0.9150 | 1.0210 | 1.0288 | 1.0388 | 0.7314 |
| Glutathione | 1.3022 | 0.8346 | 1.0307 | 1.0227 | 0.9738 | 0.8539 |
| Glyceric acid | 0.9075 | 0.9433 | 1.1123 | 1.0986 | 1.0469 | 0.9618 |
| GMP | 1.3261 | 0.8601 | 1.0421 | 1.0513 | 0.9105 | 0.8411 |
| Guanine | 1.5090 | NA | 0.4472 | 0.5738 | 1.1437 | NA |
| Guanosine | 1.6499 | NA | 0.5731 | 0.5873 | 0.9098 | NA |
| Hexose diphosphate | 1.8424 | 0.5306 | 1.0298 | 1.0315 | 1.1994 | 0.3867 |
| Hexose monophosphate | 1.2046 | 1.0037 | 1.0625 | 1.0629 | 0.6936 | 1.0146 |
| Hippuric acid | 1.2004 | 1.0386 | 1.1247 | 1.0973 | 0.7425 | 0.8706 |
| Homovanillic acid | 1.2509 | 0.7619 | 1.2375 | 1.0464 | 1.0750 | 0.7228 |
| Hydroxybutyric and or Hydroxyisobutyric acid | 0.7882 | 1.2918 | 0.8905 | 0.9443 | 0.9070 | 1.1232 |
| Hypoxanthine | 1.5459 | NA | 0.6814 | 0.6750 | 1.2133 | 0.0096 |
| IMP | 1.0778 | 0.9844 | 1.0531 | 1.0018 | 0.8187 | 1.0824 |
| Inosine | 1.4512 | NA | 0.5891 | 0.5916 | 1.0950 | NA |
| Ketocaproic and or Ketoisocaproic acid | NA | 1.3004 | 0.7868 | 0.7501 | NA | 1.0082 |
| Lactic acid | 0.9131 | 1.1626 | 0.9608 | 1.0256 | 0.8145 | 1.1189 |
| Malic acid | 0.8238 | 1.3315 | 1.0762 | 1.0436 | 0.6272 | 1.1376 |
| Malondialdehyde | 0.9073 | 1.1189 | 0.9962 | 1.1085 | 0.8913 | 1.0128 |
| Myo-inositol | 0.9224 | 1.1843 | 1.0879 | 1.0824 | 0.7615 | 1.0183 |
| N-Acetylglutamic acid | 1.3554 | 0.8028 | 1.0696 | 1.0400 | 1.0866 | 0.6821 |
| NAD+ | NA | 1.1100 | 0.5975 | 0.6084 | NA | 1.4194 |
| Oxalic acid | 1.0278 | 0.9223 | 1.0146 | 0.9463 | 1.0303 | 1.0457 |
| Oxidized glutathione | 1.2471 | 1.0672 | 1.0056 | 1.1261 | 1.2298 | 0.3681 |
| Pantothenic acid | 1.0699 | 1.0615 | 1.1508 | 1.0460 | 0.7450 | 0.9924 |
| Pentose 5-phosphate | 2.4662 | 0.1524 | 0.9323 | 0.9852 | 1.3120 | 0.1244 |
| Pseudouridine | 0.7641 | 1.3800 | 1.0639 | 1.0411 | 0.8023 | 0.9836 |
| Ribitol | 0.6244 | 1.4580 | 1.0799 | 1.0741 | 0.4746 | 1.3403 |
| sn-Glycero-3-phosphate | 0.8544 | 1.0934 | 1.1114 | 1.0825 | 0.7885 | 1.1345 |
| Sorbitol | 0.8058 | 1.3595 | 1.0738 | 1.0752 | 0.6101 | 1.1252 |
| Suberic acid | 1.0374 | 0.9547 | 1.1298 | 1.1313 | 0.9278 | 0.9060 |
| Succinic acid | 1.0021 | 1.0328 | 1.0302 | 1.0245 | 0.9099 | 1.0187 |
| Taurdeoxycholic and or Taurochenodeoxycholic acid | 0.9420 | 1.4801 | 1.0964 | 1.0562 | 0.5662 | 0.9100 |
| UDP | 1.0287 | 1.0292 | 1.0521 | 1.0380 | 1.0047 | 0.8773 |
| UDP-galactose or UDP-glucose | 1.0798 | 1.0562 | 1.0302 | 1.0303 | 0.9702 | 0.8535 |
| UMP | 1.4437 | 0.7864 | 1.0336 | 1.0427 | 1.0150 | 0.7040 |
| Uracil | 2.2207 | 0.2351 | 0.9928 | 0.9837 | 1.3751 | 0.1848 |
| Uric acid | 0.9086 | 1.1364 | 0.9801 | 1.0515 | 0.8225 | 1.1114 |
| Uridine | 2.4201 | 0.1898 | 1.0081 | 0.9788 | 1.2512 | 0.1477 |
| Xanthine | 0.6015 | 1.4313 | 1.0211 | 1.0345 | 0.7002 | 1.2299 |
Factors:
| F1 | Sample source:T-cells | Genotype:ankrd55 ko | Treatment:25ng/mL IL-6 and 2ng/mL TGF-b1 |
| F2 | Sample source:T-cells | Genotype:ankrd55 ko | Treatment:No added cytokines |
| F3 | Sample source:T-cells | Genotype:NA | Treatment:QC-drift_correction |
| F4 | Sample source:T-cells | Genotype:NA | Treatment:QC-pooled_ref |
| F5 | Sample source:T-cells | Genotype:WT | Treatment:25ng/mL IL-6 and 2ng/mL TGF-b1 |
| F6 | Sample source:T-cells | Genotype:WT | Treatment:No added cytokines |
