Data for (Study ST004223)
(Analysis AN007026)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|
| CAR 14:0 | NA | 1.0000 | NA | 1.0000 | NA | NA | NA | NA |
| CAR 16:0 | 0.8024 | 1.4043 | 0.7021 | 1.0298 | NA | NA | NA | NA |
| CAR 16:1 | NA | NA | NA | NA | NA | NA | NA | NA |
| CAR 18:0 | NA | 1.0000 | 1.0000 | 1.0000 | NA | NA | NA | NA |
| CAR 18:1 | 0.7333 | 1.4667 | 0.7333 | 1.0267 | NA | NA | NA | NA |
| CAR 20:1 | NA | NA | NA | NA | NA | NA | NA | NA |
| CAR 20:4 | NA | NA | NA | NA | NA | NA | NA | NA |
| HexCer 18:1;O2/18:0 | 0.1407 | 0.1592 | 0.1069 | 0.1310 | 1.3167 | 1.2540 | 1.2727 | 1.0986 |
| HexCer 18:1;O2/18:0;O | 0.3417 | 0.4292 | 0.3034 | 0.3612 | 1.2243 | 1.2269 | 1.0879 | 1.1747 |
| HexCer 18:1;O2/20:0 | 0.0973 | 0.1426 | 0.0872 | 0.1204 | 1.2006 | 1.3978 | 1.1730 | 1.2282 |
| HexCer 18:1;O2/20:0;O | 0.3477 | 0.5727 | 0.3425 | 0.4566 | 1.0448 | 1.2983 | 1.0673 | 1.2475 |
| HexCer 18:1;O2/21:0;O | 0.2001 | 0.3255 | 0.1608 | 0.2904 | 1.1069 | 1.3170 | 1.1655 | 1.2671 |
| HexCer 18:1;O2/22:0 | 0.1151 | 0.1644 | 0.0962 | 0.1544 | 1.1525 | 1.3956 | 1.2058 | 1.2228 |
| HexCer 18:1;O2/22:0;O | 0.2761 | 0.4480 | 0.2768 | 0.3697 | 1.0318 | 1.3184 | 1.1179 | 1.2905 |
| HexCer 18:1;O2/22:1 | 0.2049 | 0.2984 | 0.1746 | 0.3461 | 1.0484 | 1.3865 | 1.1582 | 1.2592 |
| HexCer 18:1;O2/22:2;O | 0.3148 | 0.4806 | 0.2604 | 0.4872 | 1.0878 | 1.3106 | 1.1710 | 1.1166 |
| HexCer 18:1;O2/23:0, 18:1;O2/22:1;O | 0.2465 | 0.3524 | 0.2350 | 0.3369 | 1.1513 | 1.2703 | 1.2591 | 1.0991 |
| HexCer 18:1;O2/23:0;O | 0.3450 | 0.4968 | 0.3449 | 0.4324 | 1.0967 | 1.2392 | 1.1626 | 1.1706 |
| HexCer 18:1;O2/24:0 | 0.1025 | 0.1357 | 0.0966 | 0.1371 | 1.1571 | 1.4084 | 1.2306 | 1.1941 |
| HexCer 18:1;O2/24:0;O | 0.2213 | 0.3140 | 0.2290 | 0.2737 | 1.0848 | 1.3561 | 1.1539 | 1.2501 |
| HexCer 18:1;O2/24:1 | 0.1689 | 0.2537 | 0.1649 | 0.2599 | 1.0976 | 1.3869 | 1.1936 | 1.2150 |
| HexCer 18:1;O2/24:1;O, 18:1;O2/25:0 | 0.3247 | 0.5525 | 0.3659 | 0.5190 | 0.9849 | 1.3175 | 1.0971 | 1.2555 |
| HexCer 18:1;O2/24:2 | 0.2277 | 0.3607 | 0.2294 | 0.4198 | 1.0592 | 1.4219 | 1.2081 | 1.0887 |
| HexCer 18:1;O2/25:1, 18:1;O2/24:2;O | 0.3267 | 0.5109 | 0.3507 | 0.5500 | 1.0362 | 1.2929 | 1.1483 | 1.1697 |
| HexCer 18:1;O2/25:1;O, 18:1;O2/26:0 | 0.6687 | 1.1624 | 0.8543 | 1.3855 | NA | NA | NA | NA |
| LPC 14:1 | 0.9334 | 0.7993 | 1.0790 | 1.2708 | NA | NA | NA | NA |
| LPC 16:0 | 0.7757 | 0.7058 | 0.8823 | 0.7503 | 1.0537 | 1.0508 | 1.1794 | 0.9552 |
| LPC 18:0 | 0.6262 | 0.6467 | 0.6539 | 0.6208 | 1.0347 | 1.1504 | 1.1435 | 1.0786 |
| LPC 18:1 | 0.5155 | 0.4726 | 0.5658 | 0.6217 | 1.0760 | 1.2017 | 1.1522 | 1.0867 |
| LPC 20:1 | NA | NA | NA | NA | 0.8423 | 1.2008 | 0.8918 | 1.0983 |
| LPC 20:4 | 1.0709 | 0.8556 | 1.1204 | 0.9778 | NA | NA | NA | NA |
| LPC 22:6 | 0.8098 | 0.6625 | 1.0674 | 0.9276 | 1.0411 | 1.0577 | 1.1603 | 0.8957 |
| LPE 16:0 | 0.6287 | 0.5301 | 0.6481 | 0.5664 | 1.0810 | 1.0251 | 1.2294 | 1.1111 |
| LPE 16:1 | 0.8789 | 0.6749 | 0.9378 | 0.9781 | 1.0692 | 0.8377 | 1.1819 | 1.0537 |
| LPE 18:0 | 0.8146 | 0.6643 | 0.8689 | 0.6866 | 0.9943 | 0.9123 | 1.2720 | 1.0820 |
| LPE 18:1 | 0.2258 | 0.3117 | 0.2461 | 0.3114 | 1.2471 | 1.2827 | 1.1620 | 1.1137 |
| LPE 18:2 | NA | NA | NA | NA | 1.0924 | 0.9895 | 1.0431 | 0.8529 |
| LPE 20:1 | 0.1420 | 0.2742 | 0.1442 | 0.2329 | 1.1310 | 1.4334 | 1.1229 | 1.2251 |
| LPE 20:2 | NA | NA | NA | NA | 1.0842 | 1.1018 | 0.8368 | 0.9847 |
| LPE 20:3 | 0.5038 | 0.6348 | 0.5290 | 0.5078 | 1.2360 | 1.2027 | 1.0479 | 1.0109 |
| LPE 20:4 | 0.9121 | 0.9471 | 0.8875 | 0.8843 | 1.0855 | 1.0786 | 0.9561 | 0.9774 |
| LPE 22:4 | 0.6070 | 0.7230 | 0.5562 | 0.6185 | 1.1229 | 1.3114 | 0.9185 | 1.0728 |
| LPE 22:5 | NA | NA | NA | NA | 1.1010 | 1.1171 | 0.8844 | 0.8991 |
| LPE 22:6 | 1.5310 | 1.4408 | 1.7141 | 1.3737 | 0.9350 | 0.8807 | 0.8160 | 0.8006 |
| LPE P-16:0 | 0.3899 | 0.2850 | 0.3628 | 0.3351 | 1.1392 | 0.9573 | 1.4082 | 1.2082 |
| LPE P-18:0 | NA | NA | NA | NA | 0.9592 | 0.8244 | 1.1935 | 1.0072 |
| LPE P-18:1 | 0.1862 | 0.1822 | 0.1937 | 0.2505 | 1.2039 | 1.0954 | 1.3334 | 1.2489 |
| PC 14:0/16:0 | 1.3013 | 1.4961 | 1.1802 | 1.3165 | 0.9815 | 0.8994 | 0.8137 | 0.9346 |
| PC 16:0/16:0 | 1.6653 | 1.7414 | 1.7742 | 1.5803 | 0.8254 | 0.7893 | 0.7503 | 0.8782 |
| PC 16:0/18:0 | 1.4897 | 1.6791 | 1.5422 | 1.3578 | 0.8524 | 0.8472 | 0.7961 | 0.9347 |
| PC 16:0/18:1 | 0.8035 | 0.8603 | 0.7942 | 0.8409 | 1.0383 | 1.0813 | 1.0076 | 1.0735 |
| PC 16:0/18:2 | 0.8816 | 0.8251 | 0.8411 | 0.7827 | 0.9799 | 1.0074 | 1.1937 | 0.9897 |
| PC 16:0/22:6, 18:2/20:4 | 0.8683 | 0.8392 | 0.8858 | 0.8897 | 1.0447 | 0.9954 | 1.1055 | 0.9904 |
| PC 16:1/16:0, 14:1/18:0 | 0.9554 | 0.9630 | 0.8463 | 0.8205 | 1.0831 | 0.9301 | 1.1071 | 0.9656 |
| PC 18:0/18:0 | NA | NA | NA | NA | 0.9570 | 1.0264 | 0.9428 | 1.0890 |
| PC 18:0/18:1 | 0.5857 | 0.7402 | 0.5463 | 0.7513 | 1.0305 | 1.2023 | 0.9847 | 1.1862 |
| PC 18:0/18:2, 18:1/18:1 | 0.5969 | 0.7286 | 0.5610 | 0.6903 | 0.9961 | 1.1997 | 1.0272 | 1.1927 |
| PC 18:0/20:1, P-18:1/22:6 | 0.1257 | 0.2037 | 0.1039 | 0.2200 | 1.0653 | 1.3949 | 1.0339 | 1.4887 |
| PC 18:0/20:2, P-18:2/22:6 | 0.2234 | 0.3877 | 0.2297 | 0.3792 | 0.9988 | 1.3776 | 1.0109 | 1.4400 |
| PC 18:0/20:3 | 0.9249 | 1.0143 | 0.9226 | 0.8287 | 0.9465 | 1.1347 | 0.9804 | 1.0323 |
| PC 18:0/22:2, 20:0/20:2 | NA | NA | NA | NA | 0.8094 | 1.1850 | 0.8211 | 1.2358 |
| PC 18:0/22:4, 20:0/20:4, 20:2/20:2 | 1.1708 | 1.2856 | 0.9491 | 1.1329 | 0.8781 | 1.0911 | 0.8867 | 0.9910 |
| PC 18:0/22:5 | 0.8942 | 0.9551 | 0.7418 | 0.8779 | 0.9251 | 1.1337 | 0.9484 | 1.1538 |
| PC 18:0/22:6 | 0.9254 | 0.9880 | 0.9236 | 1.0119 | 1.0157 | 1.0170 | 1.0014 | 1.0087 |
| PC 18:1/18:2, 16:0/20:3 | 1.0379 | 0.9774 | 0.9081 | 0.9402 | 0.9429 | 0.9909 | 1.1261 | 0.9589 |
| PC 18:1/20:4, 16:0/22:5 | 1.4471 | 1.4361 | 1.2172 | 1.2878 | 0.8509 | 0.9239 | 0.9260 | 0.8931 |
| PC 18:1/22:6, 18:2/22:5 | 0.9181 | 0.9535 | 0.9073 | 0.9745 | 1.0078 | 1.0205 | 1.0466 | 0.9899 |
| PC 18:2/18:2, 16:0/20:4 | 1.8993 | 1.7610 | 1.5800 | 1.5579 | 0.8024 | 0.7721 | 0.8600 | 0.7471 |
| PC 18:2/20:2, 18:0/20:4 | 1.8846 | 1.8370 | 1.5028 | 1.5941 | 0.7970 | 0.8214 | 0.7674 | 0.7970 |
| PC 18:2/22:6 | NA | NA | NA | NA | 0.8192 | 0.8925 | 1.3433 | 0.9240 |
| PC 20:0/22:1 | NA | NA | NA | NA | 0.9961 | 1.0965 | 0.8949 | 1.0252 |
| PC 20:0/22:2, 20:2/22:0 | NA | NA | NA | NA | 0.9110 | 1.1201 | 0.9121 | 1.0796 |
| PC 22:6/22:6 | NA | NA | NA | NA | 1.1051 | 0.9640 | 1.0299 | 0.8805 |
| PC O-16:0/18:0 | 1.1016 | 1.0812 | 1.1169 | 0.8690 | 1.0433 | 0.9418 | 0.9646 | 0.9928 |
| PC O-16:0/20:0 | 1.0330 | 1.1905 | 0.8010 | 0.8844 | NA | NA | NA | NA |
| PC O-18:0/18:1, P-18:0/18:0 | 0.3432 | 0.3649 | 0.2701 | 0.2815 | 1.1738 | 1.2263 | 1.0946 | 1.2770 |
| PC P-14:0/16:0 | 1.8072 | 1.8837 | 1.5203 | 1.9047 | 0.8209 | 0.7503 | 0.7144 | 0.8303 |
| PC P-16:0/18:0, P-18:0/16:0, O-18:1/16:0, O-16:0/18:1 | 0.5477 | 0.5406 | 0.4241 | 0.4918 | 1.1406 | 1.1702 | 1.0524 | 1.1933 |
| PC P-18:0/18:1, P-18:1/18:0 | NA | NA | NA | NA | 0.9178 | 1.0545 | 0.8947 | 1.1612 |
| PC P-18:0/20:0, P-16:0/22:0 | 0.4200 | 0.4845 | 0.3920 | 0.3920 | 1.0531 | 1.2550 | 1.1028 | 1.2503 |
| PC P-18:1/20:1, P-16:1/22:1 | 0.9323 | 0.9567 | 0.8256 | 0.7784 | 0.9660 | 1.1443 | 0.8949 | 1.1511 |
| PC P-20:1/22:6 | NA | NA | NA | NA | 0.9685 | 1.0991 | 0.8801 | 1.0721 |
| PC P-21:1/22:5 | NA | NA | NA | NA | 0.9279 | 1.0694 | 0.9358 | 1.0857 |
| PC P-21:1/22:6 | NA | NA | NA | NA | 1.0675 | 1.0093 | 1.0289 | 0.8778 |
| SM 18:1;O2/16:0 | 0.2958 | 0.2792 | 0.2393 | 0.2202 | 1.4201 | 1.2622 | 1.0565 | 1.0670 |
| SM 18:1;O2/18:0 | 1.1482 | 1.0857 | 1.0186 | 0.9905 | 1.0249 | 0.9585 | 0.9795 | 0.9510 |
| SM 18:1;O2/18:1 | 1.9176 | 1.7908 | 1.3836 | 1.7133 | 0.8579 | 0.8181 | 0.6883 | 0.8177 |
| SM 18:1;O2/20:0 | 0.3558 | 0.3782 | 0.3942 | 0.3713 | 1.2364 | 1.1796 | 1.0898 | 1.1969 |
| SM 18:1;O2/20:1 | NA | NA | NA | NA | 1.0789 | 1.0423 | 0.7255 | 1.1531 |
| SM 18:1;O2/21:0 | NA | NA | NA | NA | 1.0371 | 0.9594 | 1.1000 | 0.8905 |
| SM 18:1;O2/21:1 | NA | NA | NA | NA | 0.9663 | 0.9909 | 0.9984 | 1.0508 |
| SM 18:1;O2/22:0 | 0.0738 | 0.0713 | 0.0646 | 0.0797 | 1.2655 | 1.2780 | 1.2357 | 1.2551 |
| SM 18:1;O2/23:0 | 0.1563 | 0.1496 | 0.1543 | 0.1234 | 1.3600 | 1.1370 | 1.2799 | 1.1518 |
| SM 18:1;O2/23:1 | NA | NA | NA | NA | 1.0566 | 0.9856 | 0.9939 | 0.9563 |
| SM 18:1;O2/24:0 | 0.0403 | 0.0493 | 0.0460 | 0.0473 | 1.2772 | 1.3062 | 1.2666 | 1.2091 |
| SM 18:1;O2/24:1 | 0.0944 | 0.1133 | 0.0889 | 0.1263 | 1.2061 | 1.2810 | 1.2705 | 1.2403 |
| SM 18:1;O2/24:2 | NA | NA | NA | NA | 1.0171 | 1.1479 | 0.9415 | 0.8922 |
Factors:
| F1 | Sample source:mouse cerebrum | genotype:Cre+ |
| F2 | Sample source:mouse cerebrum | genotype:Cre- |
| F3 | Sample source:mouse cerebrum | genotype:Trem2 KO/Cre+ |
| F4 | Sample source:mouse cerebrum | genotype:Trem2 KO/Cre- |
| F5 | Sample source:mouse spinal cord | genotype:Cre+ |
| F6 | Sample source:mouse spinal cord | genotype:Cre- |
| F7 | Sample source:mouse spinal cord | genotype:Trem2 KO/Cre+ |
| F8 | Sample source:mouse spinal cord | genotype:Trem2 KO/Cre- |
