Data for (Study ST004223)
(Analysis AN007028)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 |
|---|---|---|---|---|---|---|---|---|
| BMP 18:0_20:4 | 1.1993 | 1.4849 | 1.0922 | 1.3021 | 0.8893 | 0.9288 | 0.9423 | 0.9280 |
| BMP 18:1_20:4 | 1.0413 | 0.9277 | 1.1596 | 0.9012 | NA | NA | NA | NA |
| BMP 18:1_22:6 | 0.7833 | 0.8255 | 0.7960 | 0.7429 | 1.1876 | 0.9868 | 1.2213 | 0.7960 |
| BMP 18:2_20:4, 16:0_22:6 | 0.6358 | 0.5992 | 0.7275 | 0.6163 | 1.1494 | 0.9821 | 1.3124 | 0.9225 |
| BMP 20:4_22:6 | 1.0624 | 0.9984 | 1.0329 | 0.8883 | NA | NA | NA | NA |
| BMP 22:6_22:6 | 0.9362 | 1.0191 | 1.0353 | 0.9842 | 1.0336 | 1.0091 | 1.0556 | 0.9014 |
| CL 18:1/18:1/16:1/16:1 | NA | NA | NA | NA | 1.1073 | 0.7531 | 1.3202 | 0.7618 |
| CL 18:1/18:1/18:1/16:0, 18:0/18:1/18:1/16:1 | NA | NA | NA | NA | 1.0664 | 0.9778 | 0.9919 | 0.9554 |
| CL 18:1/18:1/18:1/16:1, 18:2/18:1/18:1/16:0 | 1.0754 | 1.1205 | 1.0188 | 1.0279 | 1.0655 | 0.9153 | 1.0408 | 0.8840 |
| CL 18:1/18:1/18:1/18:1 | 0.7507 | 0.9119 | 0.7694 | 0.9035 | 1.0811 | 1.0282 | 1.0807 | 0.9858 |
| CL 18:1/18:2/18:2/20:2 | 1.3205 | 1.4782 | 1.2868 | 1.3642 | 0.9261 | 0.8933 | 0.9244 | 0.8381 |
| CL 18:2/18:1/18:1/16:1, 18:1/18:1/18:1/16:2, 18:2/18:1/18:0/16:2, 18:2/18:2/18:0/16:1 | 1.0665 | 1.0694 | 1.1260 | 0.9748 | 1.0401 | 0.8833 | 1.1370 | 0.8466 |
| CL 18:2/18:1/18:1/18:1 | 1.1459 | 1.1706 | 1.1761 | 1.0666 | 1.0447 | 0.9082 | 1.0189 | 0.8515 |
| CL 18:2/18:2/16:1/22:6 | 0.9916 | 1.1078 | 1.0147 | 0.8706 | NA | NA | NA | NA |
| CL 18:2/18:2/18:2/16:1 | 1.0688 | 1.0247 | 1.0185 | 0.8593 | NA | NA | NA | NA |
| CL 18:2/18:2/18:2/20:2 | 0.8950 | 0.9908 | 0.8815 | 0.8917 | 1.0581 | 1.0107 | 1.0490 | 0.9641 |
| CL 18:2/18:2/18:2/20:3 | NA | NA | NA | NA | 1.0197 | 0.9487 | 1.0771 | 0.9413 |
| CL 18:2/18:2/18:2/20:4 | 1.9418 | 2.1049 | 1.8195 | 1.8266 | 0.7254 | 0.7041 | 0.8443 | 0.6679 |
| CL 18:2/18:2/18:2/22:5, 18:1/18:2/18:2/22:6 | 0.9850 | 1.1238 | 0.8476 | 0.9943 | NA | NA | NA | NA |
| CL 18:2/18:2/18:2/22:6 | NA | NA | NA | NA | NA | NA | NA | NA |
| CL 18:2/18:2/20:1/22:6, 18:1/18:2/20:2/22:6 | 1.3588 | 1.5526 | 1.2502 | 1.4709 | 0.9199 | 0.8722 | 0.9152 | 0.8172 |
| CL 18:2/18:2/20:2/22:6, 18:1/18:2/20:3/22:6 | 1.5534 | 1.8431 | 1.4493 | 1.7258 | 0.8306 | 0.8281 | 0.8282 | 0.7819 |
| CL 18:2/18:2/20:3/22:6 | 0.9195 | 1.0952 | 0.9367 | 1.0491 | NA | NA | NA | NA |
| CL 18:2/18:2/20:4/22:6 | 0.9057 | 1.0636 | 0.9971 | 1.0580 | NA | NA | NA | NA |
| CL 18:2/18:2/22:6/22:6 | 0.8549 | 1.0853 | 1.0120 | 1.0912 | NA | NA | NA | NA |
| CL 18:2/18:3/20:4/22:6 | 0.9354 | 1.1349 | 1.0149 | 0.9167 | NA | NA | NA | NA |
| CL 20:4/18:1/16:1/16:0, 18:2/18:2/18:1/16:1 | 1.2547 | 1.2808 | 1.2625 | 1.1857 | 0.8835 | 0.8378 | 1.1815 | 0.7929 |
| CL 20:4/18:1/18:1/16:0, 20:3/18:1/18:1/16:1, 20:3/18:1/18:1/16:1 | 1.2767 | 1.2993 | 1.2043 | 1.2106 | 0.9553 | 0.9024 | 1.0051 | 0.8381 |
| CL 20:4/18:1/18:1/18:0, 20:3/18:1/18:1/18:1 | NA | NA | NA | NA | 1.0996 | 0.9304 | 1.1076 | 0.8317 |
| CL 20:4/18:2/18:1/16:0, 20:4/18:1/18:1/16:1 | 1.3082 | 1.3897 | 1.1892 | 1.2400 | 0.9069 | 0.8692 | 1.0410 | 0.8403 |
| CL 20:4/18:2/18:1/16:1 | 0.9597 | 1.0223 | 0.9818 | 0.9087 | 0.8176 | 0.8695 | 1.4234 | 0.8943 |
| CL 20:4/20:4/18:1/18:1 | 0.9850 | 1.1077 | 0.9658 | 1.0011 | 1.0167 | 0.9871 | 1.0325 | 0.9335 |
| CL 20:4/20:4/22:6/22:5, 18:2/22:6/22:6/22:5 | 0.7857 | 1.0325 | 0.9697 | 1.2853 | NA | NA | NA | NA |
| CL 22:6/18:1/18:1/18:1, 20:4/20:3/18:1/18:1 | 0.9168 | 1.0696 | 0.9151 | 0.9571 | 1.0428 | 1.0133 | 1.0103 | 0.9639 |
| LysoCL 18:1/18:1/18:1 | 0.3411 | 0.3980 | 0.4775 | 0.4775 | 1.1143 | 1.1687 | 1.2848 | 1.0745 |
| LysoCL18:1/18:1/22:6 | 0.4556 | 0.5316 | 0.6202 | 0.6379 | 1.0632 | 1.2683 | 1.0463 | 1.1419 |
| LysoCL18:2/18:2/20:3, 18:2/18:1/20:4 | 0.5614 | 0.5614 | 0.5614 | 0.5614 | 1.0159 | 1.2410 | 1.1228 | 0.9981 |
| PA16:0/16:0 | 0.5058 | 0.7905 | 0.5344 | 0.6813 | 1.0847 | 1.1672 | 1.0561 | 1.1133 |
| PA 16:0/16:1 | 0.2585 | 0.4326 | 0.2556 | 0.3776 | 1.1424 | 1.1923 | 1.2249 | 1.1843 |
| PA 16:0/18:1 | 0.2180 | 0.4043 | 0.1967 | 0.3429 | 1.0790 | 1.3826 | 1.0560 | 1.3025 |
| PA 16:0/18:2 | 0.2976 | 0.4928 | 0.3024 | 0.4301 | 1.1296 | 1.2874 | 1.1040 | 1.1797 |
| PA 18:0/18:1 | 0.3114 | 0.5859 | 0.2554 | 0.4931 | 1.0070 | 1.4244 | 0.9517 | 1.3124 |
| PA 18:0/18:2, 18:1/18:1 | 0.1911 | 0.3768 | 0.1769 | 0.3124 | 0.9718 | 1.4811 | 1.0002 | 1.4210 |
| PA 18:0/20:1 | 0.1290 | 0.2716 | 0.0940 | 0.2207 | 0.9982 | 1.5559 | 0.9791 | 1.4390 |
| PA 18:0/20:2 | 0.0845 | 0.2484 | 0.0712 | 0.1841 | 0.8859 | 1.6412 | 0.9235 | 1.5851 |
| PA 18:0/20:4 | 0.2374 | 0.4264 | 0.1893 | 0.3254 | 1.0769 | 1.3817 | 1.0641 | 1.2878 |
| PA 18:0/22:4 | 0.2821 | 0.6708 | 0.2088 | 0.4253 | 0.9728 | 1.4668 | 0.9257 | 1.3500 |
| PA P18:0/20:4 | NA | NA | NA | NA | 0.8993 | 1.1698 | 0.8774 | 1.0812 |
| PG 16:0/16:0 | 0.5555 | 0.5752 | 0.6319 | 0.6027 | 1.1364 | 1.0846 | 1.1410 | 1.0936 |
| PG 16:0/18:1 | 0.8116 | 0.7621 | 0.8403 | 0.7877 | 1.0811 | 1.0210 | 1.1226 | 0.9872 |
| PG 18:0/18:1 | 2.2983 | 1.5011 | 2.3449 | 1.8510 | 0.7750 | 0.7487 | 0.7188 | 0.6488 |
| PG 18:1/18:1 | 0.8326 | 0.7485 | 0.8742 | 0.8365 | 1.1167 | 0.9383 | 1.1967 | 0.9219 |
| PG 18:2/18:2 | 1.8013 | 1.7062 | 1.8727 | 1.6480 | 0.7966 | 0.7096 | 0.9155 | 0.7213 |
| PI 16:0/16:0 | 0.4972 | 0.5035 | 0.5254 | 0.6173 | 1.1695 | 1.1060 | 1.1633 | 1.0726 |
| PI 16:0/16:1 | 1.1952 | 0.8779 | 1.0070 | 0.8676 | NA | NA | NA | NA |
| PI 16:0/18:1 | 2.1249 | 1.6845 | 2.0086 | 1.8058 | 0.7392 | 0.7405 | 0.7813 | 0.7197 |
| PI 16:0/18:2 | 1.1778 | 0.9488 | 1.1042 | 1.0601 | 1.0890 | 0.9454 | 0.9769 | 0.8888 |
| PI 16:0/20:4 | 1.0223 | 0.9194 | 1.1205 | 0.9691 | NA | NA | NA | NA |
| PI 16:1/20:4 | 0.0347 | 0.0251 | 0.0376 | 0.0254 | 1.3091 | 1.2527 | 1.2832 | 1.2272 |
| PI 18:0/18:1 | 0.7227 | 1.0509 | 0.8524 | 1.2245 | 0.9218 | 1.1037 | 0.9898 | 1.0550 |
| PI 18:0/18:2 | 0.3148 | 0.4014 | 0.3715 | 0.4817 | 1.0688 | 1.2946 | 1.1322 | 1.2042 |
| PI 18:0/20:4 | 1.2448 | 1.1289 | 1.2121 | 1.1415 | 0.9464 | 0.9836 | 0.9351 | 0.9310 |
| PI 18:0/22:4 | 0.5000 | 0.6944 | 0.5417 | 0.7667 | 1.0159 | 1.2544 | 1.0476 | 1.1204 |
| PI 18:0/22:6 | 0.2824 | 0.2896 | 0.3615 | 0.3873 | 1.1755 | 1.2120 | 1.2033 | 1.1622 |
| PI 18:1/20:4 | 1.0565 | 0.9095 | 1.0588 | 0.9461 | 0.9401 | 1.0779 | 0.9632 | 1.0406 |
| PI 18:1/22:6 | 0.3399 | 0.2864 | 0.4296 | 0.3966 | 1.1268 | 1.1967 | 1.2150 | 1.1824 |
| PI 18:2/20:4, 16:0-22:6 | NA | NA | NA | NA | 1.0141 | 0.9968 | 1.0070 | 0.9788 |
| PI P18:0/20:4 | 1.8146 | 1.7212 | 2.3753 | 2.2513 | 0.7426 | 0.7338 | 0.7819 | 0.6254 |
| PS 16:0/18:1 | 0.8235 | 0.7963 | 0.7284 | 0.6977 | 1.0703 | 1.0517 | 1.1032 | 1.0238 |
| PS 18:0/18:1 | 0.3298 | 0.4952 | 0.3030 | 0.4909 | 1.1178 | 1.2469 | 1.1232 | 1.1833 |
| PS 18:0/18:2 | 0.2842 | 0.3496 | 0.2916 | 0.3329 | 1.1129 | 1.2812 | 1.1495 | 1.2349 |
| PS 18:0/20:1 | 0.1274 | 0.2078 | 0.1073 | 0.2014 | 1.0865 | 1.4012 | 1.1069 | 1.3744 |
| PS 18:0/20:2 | 0.1232 | 0.2140 | 0.1113 | 0.2123 | 1.0258 | 1.4313 | 1.0938 | 1.4245 |
| PS 18:0/20:4 | 0.6092 | 0.8139 | 0.5584 | 0.7999 | 1.0406 | 1.1145 | 1.1060 | 1.0758 |
| PS 18:0/22:6 | 2.1256 | 2.1608 | 2.0389 | 1.8596 | 0.7069 | 0.7061 | 0.7095 | 0.6968 |
| PS 18:1/20:4 | 0.3600 | 0.4438 | 0.3408 | 0.4121 | 1.0967 | 1.2297 | 1.1714 | 1.1888 |
| PS 18:1/22:6 | 1.4560 | 1.4397 | 1.3534 | 1.2663 | 0.8507 | 0.9068 | 0.9191 | 0.8905 |
| PS 18:2/20:4 | 1.1556 | 1.0111 | 0.9652 | 0.7967 | NA | NA | NA | NA |
| PS 20:0/20:1, 18:0/22:1 | 0.2306 | 0.2411 | 0.1726 | 0.2264 | 1.1944 | 1.2793 | 1.1917 | 1.2056 |
| PS 20:0/20:2, 18:0/22:2 | 0.2434 | 0.3608 | 0.2091 | 0.3549 | 1.0578 | 1.3682 | 1.0805 | 1.3122 |
| PS 20:0/20:4, 18:0/22:4 | 1.1228 | 1.3566 | 0.9305 | 1.1722 | 0.8936 | 1.0558 | 0.8777 | 1.0089 |
| PS 20:0/22:1 | 1.1157 | 0.9869 | 0.8805 | 0.9494 | NA | NA | NA | NA |
| PS 20:0/22:2 | 0.2443 | 0.2991 | 0.2138 | 0.2913 | 1.1637 | 1.3073 | 1.1617 | 1.1952 |
| PS 20:0/22:4 | 0.3712 | 0.5672 | 0.3111 | 0.5343 | 1.0682 | 1.2115 | 1.1553 | 1.1873 |
| PS 20:1/22:6 | 0.4028 | 0.5020 | 0.3525 | 0.4871 | 0.9918 | 1.2952 | 1.1108 | 1.2532 |
| PS 22:4/22:0 | NA | NA | NA | NA | 0.7345 | 1.1968 | 0.7345 | 1.4119 |
| PS 22:6/22:6 | 0.3059 | 0.3390 | 0.3189 | 0.3444 | 1.2290 | 1.1551 | 1.1963 | 1.1638 |
| PS P18:0/18:1 | NA | NA | NA | NA | 1.0124 | 0.9232 | 1.1210 | 0.9256 |
| PS P18:0/18:2 | NA | NA | NA | NA | 0.9939 | 0.9820 | 1.0572 | 0.9593 |
| SHexCer 18:0;O2/24:0 | NA | NA | NA | NA | 0.8827 | 1.1029 | 0.8495 | 1.2037 |
| SHexCer 18:1;O2/22:0 | 0.1902 | 0.4057 | 0.1513 | 0.3954 | 1.0949 | 1.3259 | 1.0295 | 1.3805 |
| SHexCer 18:1;O2/22:0;O | 0.5911 | 1.3483 | 0.5599 | 1.2770 | 0.8557 | 1.1530 | 0.8347 | 1.2635 |
| SHexCer 18:1;O2/22:1;O | 0.1477 | 0.3804 | 0.1410 | 0.3544 | 1.0913 | 1.3404 | 1.0421 | 1.3933 |
| SHexCer 18:1;O2/23:0 | 0.2764 | 0.5182 | 0.2258 | 0.5057 | 1.0579 | 1.3003 | 1.0118 | 1.3531 |
| SHexCer 18:1;O2/24:0 | 0.1976 | 0.4442 | 0.1761 | 0.4462 | 1.1030 | 1.3125 | 1.0237 | 1.3566 |
| SHexCer 18:1;O2/24:0;O | 0.5484 | 1.2948 | 0.5779 | 1.3539 | 0.8708 | 1.1545 | 0.8539 | 1.2310 |
| SHexCer 18:1;O2/24:1 | 0.2641 | 0.6191 | 0.2365 | 0.6117 | 1.0011 | 1.3374 | 0.9968 | 1.3370 |
| SHexCer 18:1;O2/24:2 | 0.2902 | 0.7009 | 0.2754 | 0.6780 | 1.0810 | 1.3092 | 1.0306 | 1.1697 |
| SHexCer 18:1;O2/24:2;O | 0.1047 | 0.2834 | 0.1099 | 0.2756 | 1.0750 | 1.4181 | 1.0527 | 1.3959 |
| SHexCer 18:1;O2/25:0, 18:1;O2/24:1;O | 0.5934 | 1.4772 | 0.5799 | 1.4482 | 0.8120 | 1.1450 | 0.8322 | 1.2299 |
| SHexCer 18:1;O2/25:1 | 0.3738 | 0.8722 | 0.3336 | 0.8635 | 0.9744 | 1.2807 | 0.9507 | 1.2632 |
| SHexCer 18:1;O2/25:1;O | 0.5521 | 1.5113 | 0.4831 | 1.4270 | NA | NA | NA | NA |
Factors:
| F1 | Sample source:mouse cerebrum | genotype:Cre+ |
| F2 | Sample source:mouse cerebrum | genotype:Cre- |
| F3 | Sample source:mouse cerebrum | genotype:Trem2 KO/Cre+ |
| F4 | Sample source:mouse cerebrum | genotype:Trem2 KO/Cre- |
| F5 | Sample source:mouse spinal cord | genotype:Cre+ |
| F6 | Sample source:mouse spinal cord | genotype:Cre- |
| F7 | Sample source:mouse spinal cord | genotype:Trem2 KO/Cre+ |
| F8 | Sample source:mouse spinal cord | genotype:Trem2 KO/Cre- |
