Data for (Study ST004385)
(Analysis AN007326)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 |
|---|---|---|---|---|---|---|---|---|---|
| 1-O-Palmitoyl-Cer(d18:1/18:0) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 24-Hydroxycholesterol | 1.0111 | 1.0365 | 1.0626 | 0.9890 | 0.9821 | 0.8830 | 1.0035 | 1.0334 | 0.9978 |
| 24-Hydroxycholesterol(d7) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 3-O-SulfoLacCer(d18:1/18:0) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 4-beta-Hydroxycholesterol | 1.0521 | 1.0641 | 1.0199 | 1.0512 | 0.8296 | 0.9036 | 1.0451 | 1.0725 | 0.9365 |
| 7-keto-Cholesterol | 1.1564 | 1.0339 | 1.2606 | 1.1341 | 0.7618 | 0.5470 | 1.0239 | 1.0060 | 1.1271 |
| CE(16:1) | 0.2738 | 0.2994 | 0.1153 | 0.0905 | 0.5795 | 6.8511 | 0.1166 | 0.1079 | 0.2766 |
| CE(18:1) | 0.5851 | 0.5780 | 0.3491 | 0.2976 | 0.9790 | 5.0037 | 0.3579 | 0.3449 | 0.1744 |
| CE(18:1(d7)) | 1.1229 | 1.0606 | 0.9865 | 1.0435 | 1.1211 | 0.9041 | 1.1186 | 1.1225 | 0.2004 |
| CE(18:2) | 0.2269 | 0.1943 | 0.1605 | 0.1064 | 0.4717 | 7.0622 | 0.1391 | 0.1132 | 0.2094 |
| CE(20:4) | 0.5067 | 0.5252 | 0.3965 | 0.3340 | 0.5993 | 5.3739 | 0.3332 | 0.3649 | 0.2772 |
| CE(20:5) | 0.1506 | 0.1417 | 0.0538 | 0.0258 | 0.3518 | 7.5526 | 0.0514 | 0.0363 | 0.3933 |
| CE(22:6) | 0.4384 | 0.3968 | 0.1593 | 0.0882 | 0.9802 | 5.9953 | 0.1379 | 0.1160 | 0.4797 |
| CE HETE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| CE HODE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| CE HpODE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| CE oxoHETE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| CE oxoODE | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Cer(d18:0/16:0) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Cer(d18:0/18:0) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Cer(d18:0/24:0) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Cer(d18:0/24:1) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Cer(d18:1/16:0) | 0.9630 | 0.9420 | 0.9447 | 0.9105 | 1.0183 | 1.3957 | 0.9097 | 0.9475 | 0.9476 |
| Cer(d18:1/16:0(d7)) | 0.9754 | 0.9807 | 0.9282 | 0.9506 | 1.0094 | 1.1669 | 1.0417 | 0.9744 | 0.9544 |
| Cer(d18:1/18:0) | 0.9882 | 1.0127 | 1.0861 | 1.0113 | 0.9585 | 0.9906 | 0.9240 | 1.0593 | 0.9489 |
| Cer(d18:1/24:0) | 0.9643 | 0.9100 | 1.0135 | 0.9040 | 1.0122 | 1.4826 | 0.8864 | 1.0220 | 0.6750 |
| Cer(d18:1/24:1) | 0.9629 | 0.9785 | 0.8852 | 0.8927 | 1.0720 | 1.4462 | 0.9838 | 0.9741 | 0.6745 |
| Cholesterol | 1.0187 | 0.9520 | 0.9220 | 0.9888 | 0.9981 | 1.1307 | 0.9638 | 1.0094 | 1.0277 |
| Cholesterol(d7) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Cholesteryl hexoside | 0.9887 | 0.9716 | 0.8756 | 0.9267 | 1.0982 | 1.2630 | 0.9957 | 0.9756 | 0.8415 |
| Coenzyme Q10 | 0.9693 | 0.9972 | 1.0294 | 1.1026 | 1.1217 | 0.9279 | 1.1005 | 1.0385 | 0.5213 |
| DG(15:0/18:1(d7)) | 0.9674 | 1.0004 | 0.9810 | 0.9718 | 1.0224 | 1.0758 | 0.9650 | 0.9547 | 1.1027 |
| DG(16:0_18:1) | 0.9971 | 1.0088 | 0.9125 | 0.9376 | 1.0254 | 1.2724 | 0.9553 | 0.8943 | 0.9945 |
| DG(16:0_20:4) | 0.9355 | 0.8453 | 1.0107 | 0.9263 | 1.0303 | 1.3105 | 1.0541 | 0.8920 | 0.9923 |
| DG(18:0_18:1) | 1.0173 | 1.0080 | 0.8731 | 0.9846 | 1.1068 | 1.0519 | 1.1287 | 0.9333 | 0.8271 |
| DG(18:0_20:4) | 0.9536 | 0.8622 | 1.1283 | 0.9697 | 0.9435 | 1.0933 | 1.1283 | 0.9743 | 0.9115 |
| DG(18:0_22:6) | 0.9968 | 0.8465 | 0.9482 | 0.9559 | 1.0699 | 1.1532 | 1.1215 | 0.9335 | 0.9575 |
| DG(18:1/18:1) | 1.0548 | 0.9876 | 0.9110 | 0.9831 | 1.0925 | 1.0087 | 0.9881 | 0.9117 | 1.1042 |
| DG(18:1_20:4) | 0.9943 | 0.8722 | 1.0701 | 1.0085 | 1.0011 | 1.0015 | 1.0627 | 0.9541 | 1.0594 |
| GB3(d18:1/16:0) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| GB3(d18:1/18:0) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| GB3(d18:1/18:0(d3)) | 1.0358 | 1.0641 | 1.0509 | 1.0467 | 1.0291 | 1.1336 | 0.9389 | 0.9422 | 0.5977 |
| GB3(d18:1/24:0) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| GB3(d18:1/24:1) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| GlcCer(d18:1/16:0(d3)) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| GlcCer(d18:1(d5)/18:0) | 0.9848 | 0.9740 | 0.9896 | 1.0172 | 1.0131 | 1.1408 | 1.0063 | 0.9451 | 0.8820 |
| Glucosylsphingosine(d5) | 1.0154 | 0.9907 | 1.0272 | 1.0740 | 0.9312 | 1.1020 | 1.0258 | 0.9934 | 0.7339 |
| HexCer(d18:1/12:0) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| HexCer(d18:1/16:0) | 0.9738 | 0.9493 | 0.8727 | 0.8856 | 1.1904 | 1.3591 | 0.9610 | 0.8920 | 0.8599 |
| HexCer(d18:1/18:0) | 0.9635 | 0.9855 | 0.8893 | 0.8875 | 1.1288 | 1.3379 | 0.9925 | 0.9210 | 0.8235 |
| HexCer(d18:1/22:0) | 0.9598 | 0.9599 | 0.8967 | 0.8917 | 1.1458 | 1.3377 | 1.0946 | 0.9524 | 0.6022 |
| HexCer(d18:1/24:0) | 0.9708 | 0.9263 | 0.8449 | 0.8786 | 1.1492 | 1.3921 | 1.1436 | 0.9917 | 0.5049 |
| HexCer(d18:1/24:1) | 0.9685 | 0.9881 | 0.9179 | 0.9431 | 1.1059 | 1.1367 | 1.0991 | 0.9751 | 0.7760 |
| Hexosylsphingosine | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| LacCer(d18:1/16:0) | 1.0001 | 0.9209 | 0.7894 | 0.8789 | 1.1244 | 1.7164 | 0.8760 | 0.8244 | 0.7823 |
| LacCer(d18:1/17:0) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| LacCer(d18:1/18:0) | 1.0404 | 0.9320 | 0.9568 | 0.9869 | 1.0907 | 1.2552 | 0.9636 | 0.9155 | 0.7650 |
| LacCer(d18:1/24:0) | 1.0057 | 0.9807 | 0.9303 | 0.8362 | 1.1495 | 1.4841 | 0.9199 | 1.0134 | 0.4668 |
| LacCer(d18:1/24:1) | 1.0029 | 0.9776 | 0.9261 | 0.9286 | 1.0971 | 1.3056 | 1.0369 | 0.9349 | 0.6504 |
| Lactosylsphingosine | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| LPC(16:0) | 1.0570 | 0.9851 | 1.0272 | 1.0382 | 0.9583 | 0.9469 | 1.0550 | 1.0315 | 0.8346 |
| LPC(16:1) | 1.1983 | 0.9259 | 1.0775 | 1.1237 | 0.8205 | 0.7807 | 1.2021 | 1.1100 | 0.6022 |
| LPC(18:0) | 1.0740 | 1.0338 | 1.0033 | 1.0060 | 0.9755 | 0.9793 | 1.0149 | 1.0319 | 0.8023 |
| LPC(18:1) | 1.1063 | 0.9830 | 1.0336 | 1.0790 | 0.9385 | 0.8532 | 1.1073 | 1.0646 | 0.7242 |
| LPC(18:1(d7)) | 1.0032 | 0.9896 | 0.9940 | 1.0028 | 1.0110 | 0.9872 | 1.0218 | 0.9960 | 0.9907 |
| LPC(20:4) | 1.1855 | 0.9762 | 1.1620 | 1.1422 | 0.8081 | 0.6864 | 1.1285 | 1.1192 | 0.6532 |
| LPC(22:6) | 1.1555 | 0.9300 | 1.0304 | 1.1126 | 0.9329 | 0.8064 | 1.1656 | 1.0763 | 0.6504 |
| LPC(24:0) | 0.9347 | 0.8635 | 0.7120 | 0.7698 | 1.2054 | 1.7224 | 0.9765 | 0.9399 | 0.7929 |
| LPC(24:1) | 0.9908 | 0.8303 | 0.6791 | 0.7432 | 1.1992 | 1.7042 | 1.0256 | 0.9569 | 0.7845 |
| LPC(26:0) | 0.9927 | 0.8001 | 0.6022 | 0.7547 | 1.2462 | 1.8058 | 0.9879 | 0.8481 | 0.9372 |
| LPC(26:1) | 0.9993 | 0.8608 | 0.6878 | 0.7362 | 1.3160 | 1.6567 | 0.9419 | 0.9053 | 0.8266 |
| lyso-GB3 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| lyso-GB3-d7 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| lyso-GB4 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| MG(16:0) | 1.0933 | 1.0289 | 0.8334 | 0.9965 | 1.0996 | 1.0547 | 0.8540 | 1.0064 | 1.0552 |
| MG(16:1) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| MG(18:0) | 1.0585 | 1.0279 | 0.8376 | 1.0097 | 1.0811 | 1.0983 | 0.9118 | 1.0123 | 0.9379 |
| MG(18:1) | 1.0476 | 1.1364 | 0.7699 | 1.0315 | 1.0502 | 1.0977 | 0.9215 | 1.0498 | 0.8255 |
| MG(18:1(d7)) | 1.0179 | 1.0592 | 1.0039 | 0.9769 | 1.0429 | 0.9674 | 1.0304 | 0.9426 | 0.9312 |
| MG(20:4) | 0.9373 | 0.8122 | 1.3760 | 1.0428 | 0.8176 | 0.9179 | 1.2806 | 0.9279 | 0.8130 |
| N-Oleoylethanolamine | 1.1876 | 0.9967 | 0.9855 | 1.0854 | 0.9876 | 0.7872 | 1.0087 | 0.9545 | 1.0113 |
| N-Palmitoyl-O-phosphocholineserine | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Palmitoylethanolamine | 1.1585 | 0.9278 | 0.8996 | 0.9574 | 1.1208 | 1.0040 | 1.0095 | 0.8904 | 1.0532 |
| PC(15:0/18:1(d7)) | 1.0033 | 0.9978 | 0.9997 | 0.9976 | 1.0026 | 1.0237 | 0.9918 | 0.9683 | 1.0256 |
| PC(16:0/5:0(CHO)) | 1.0232 | 0.8223 | 0.9706 | 0.9503 | 0.9392 | 0.7709 | 0.9198 | 0.8927 | 2.1850 |
| PC(16:0/9:0(CHO)) | 0.9490 | 0.7538 | 0.8910 | 0.8955 | 0.8301 | 0.6935 | 0.9475 | 0.8560 | 2.9726 |
| PC(16:0/9:0(COOH)) | 1.0218 | 0.8594 | 0.9117 | 0.9325 | 0.9006 | 0.7501 | 1.0511 | 0.9354 | 2.0624 |
| PC(18:0/20:4(OH[S])) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| PC(18:0/20:4(OOH[S])) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| PC(34:1) | 0.9991 | 1.0039 | 0.9980 | 1.0023 | 1.0001 | 0.9880 | 1.0034 | 0.9976 | 1.0128 |
| PC(36:1) | 0.9972 | 1.0071 | 0.9992 | 1.0037 | 1.0043 | 0.9842 | 1.0055 | 0.9994 | 0.9991 |
| PC(36:2) | 0.9850 | 0.9931 | 0.9650 | 1.0090 | 1.0528 | 0.9925 | 1.0047 | 0.9863 | 1.0193 |
| PC(36:4) | 1.0018 | 1.0087 | 1.0105 | 1.0025 | 0.9861 | 0.9775 | 1.0020 | 1.0012 | 1.0164 |
| PC(38:4) | 1.0020 | 1.0107 | 1.0397 | 1.0088 | 0.9808 | 0.9539 | 0.9775 | 1.0002 | 1.0443 |
| PC(38:6) | 1.0017 | 1.0002 | 0.9862 | 0.9990 | 1.0056 | 1.0095 | 0.9987 | 0.9966 | 1.0039 |
| PC(40:5) | 0.9926 | 1.0088 | 0.9969 | 1.0040 | 1.0173 | 0.9678 | 1.0152 | 0.9923 | 1.0085 |
| PC(40:6) | 1.0000 | 1.0009 | 0.9932 | 1.0008 | 1.0079 | 0.9996 | 1.0008 | 0.9920 | 1.0080 |
| PC(O-16:0/0:0) | 1.1440 | 0.8656 | 0.9429 | 1.1107 | 1.0115 | 0.9096 | 1.1131 | 1.1213 | 0.6355 |
| PC(O-16:0/2:0) | 1.1353 | 0.9755 | 1.0364 | 1.0922 | 0.9283 | 0.8243 | 1.1298 | 1.0700 | 0.6804 |
| PC(O-18:0/2:0) | 1.1100 | 1.0310 | 1.0028 | 1.0200 | 0.9634 | 0.9576 | 1.0280 | 1.0503 | 0.7282 |
| PE(15:0/18:1(d7)) | 1.0009 | 0.9889 | 0.9760 | 0.9888 | 0.9953 | 1.0989 | 1.0259 | 1.0004 | 0.8747 |
| PE(18:0/20:4(OH[S])) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| PE(18:0/20:4(OOH[S])) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| PE(34:1) | 0.9818 | 0.9864 | 0.9742 | 1.0047 | 1.0102 | 1.0555 | 1.0308 | 0.9981 | 0.9307 |
| PE(36:1) | 0.9943 | 1.0193 | 0.9932 | 1.0142 | 1.0271 | 0.9939 | 1.0464 | 0.9949 | 0.8611 |
| PE(36:2) | 1.0002 | 0.9922 | 0.9381 | 1.0041 | 1.0685 | 0.9950 | 1.0235 | 0.9969 | 0.9692 |
| PE(36:4) | 0.9925 | 1.0182 | 1.0309 | 1.0130 | 0.9861 | 1.0091 | 0.9733 | 0.9906 | 0.9770 |
| PE(38:4) | 1.0026 | 1.0224 | 1.0464 | 1.0162 | 0.9720 | 0.9452 | 1.0001 | 1.0136 | 0.9695 |
| PE(38:5) | 1.0060 | 1.0100 | 1.0016 | 1.0204 | 1.0245 | 0.9852 | 0.9877 | 0.9778 | 0.9777 |
| PE(38:6) | 0.9950 | 1.0006 | 0.9570 | 0.9901 | 1.0414 | 1.0217 | 1.0128 | 0.9971 | 0.9738 |
| PE(40:4) | 0.9912 | 1.0334 | 1.1163 | 1.0441 | 0.9133 | 0.8941 | 1.0326 | 1.0445 | 0.8841 |
| PE(40:5) | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| PE(40:6) | 0.9927 | 0.9863 | 0.9719 | 1.0005 | 1.0365 | 1.0318 | 1.0327 | 0.9923 | 0.9254 |
| PE(40:7) | 0.9977 | 1.0020 | 0.9548 | 1.0126 | 1.0397 | 0.9820 | 1.0122 | 1.0017 | 0.9955 |
| Sitosteryl hexoside | 0.9727 | 0.8499 | 0.9846 | 1.0098 | 0.9865 | 1.1855 | 1.0087 | 1.0519 | 0.9171 |
| SM(d18:1/16:0) | 0.9915 | 0.9808 | 0.9521 | 0.9265 | 1.0235 | 1.2598 | 0.9198 | 0.9681 | 0.9631 |
| SM(d18:1/18:0) | 0.9993 | 1.0099 | 1.0214 | 0.9997 | 0.9754 | 0.9896 | 0.9885 | 1.0034 | 1.0213 |
| SM(d18:1/24:0) | 0.9329 | 0.9707 | 0.9445 | 0.9492 | 0.9878 | 1.3475 | 1.0515 | 1.0085 | 0.6789 |
| SM(d18:1/24:1) | 0.9864 | 1.0030 | 0.9511 | 0.9775 | 1.0524 | 1.0573 | 1.0231 | 0.9860 | 0.9389 |
| SM(d18:1(d9)/18:1) | 1.0236 | 0.9815 | 0.9479 | 0.9847 | 1.0453 | 1.0625 | 0.9932 | 0.9773 | 0.9735 |
| Sphinganine | 1.0582 | 1.0753 | 1.0707 | 1.0752 | 0.9470 | 0.8075 | 1.0397 | 1.0084 | 0.8634 |
| Sphinganine 1-phosphate | 1.0187 | 0.9675 | 0.9497 | 0.9566 | 1.0930 | 1.0501 | 1.0804 | 0.9458 | 0.8971 |
| Sphingosine | 0.9981 | 1.0953 | 1.0158 | 0.9779 | 1.0292 | 1.0343 | 0.9638 | 0.9988 | 0.8114 |
| Sphingosine 1-phosphate | 1.0346 | 0.9512 | 0.8182 | 0.8580 | 1.2168 | 1.3118 | 1.0148 | 0.8568 | 0.8961 |
| Sphingosine 1-phosphate-d7 | 1.0279 | 0.9531 | 1.0345 | 0.9930 | 1.0450 | 0.9678 | 1.0108 | 0.9611 | 1.0113 |
| Sphingosine 1-phosphocholine | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Sphingosine(d17:1) | 1.0240 | 0.9623 | 1.0547 | 0.9982 | 0.9702 | 1.0153 | 1.0790 | 0.9999 | 0.8274 |
| TG(15:0/18:1(d7)/15:0) | 0.9950 | 1.0117 | 1.0167 | 0.9694 | 0.9463 | 1.4482 | 1.0631 | 1.0281 | 0.2024 |
| TG(18:0_36:2) | 1.1223 | 1.0460 | 0.9456 | 0.9497 | 1.0151 | 1.2907 | 1.1187 | 1.0325 | 0.1321 |
| TG(18:1_34:2) | 1.0889 | 0.9944 | 0.9142 | 0.8804 | 0.7722 | 1.8346 | 0.9281 | 1.0382 | 0.2484 |
| TG(18:1_34:3) | 1.2349 | 0.9657 | 1.0124 | 0.8297 | 0.5833 | 1.3094 | 1.0487 | 1.4107 | 0.3421 |
| TG(20:4_32:1) | 1.0655 | 1.0027 | 1.0639 | 0.9909 | 0.9067 | 1.4671 | 0.9660 | 0.9335 | 0.3393 |
| TG(20:4_34:2) | 1.1848 | 1.0355 | 1.1212 | 1.0471 | 1.0216 | 1.1071 | 0.9266 | 0.9506 | 0.3422 |
| TG(20:4_34:3) | 1.0740 | 0.9623 | 1.1436 | 0.9851 | 0.9341 | 1.3866 | 0.9036 | 0.9542 | 0.4273 |
| TG(20:4_36:0) | 0.9850 | 1.1445 | 1.1393 | 1.1002 | 1.0247 | 0.9471 | 1.0815 | 1.0946 | 0.1386 |
| TG(20:4_36:2) | 1.2648 | 1.0993 | 1.2275 | 1.0879 | 0.9065 | 0.8260 | 0.9768 | 1.0749 | 0.2270 |
| TG(20:4_36:3) | 1.2165 | 1.0655 | 1.1625 | 0.9931 | 1.0145 | 0.9943 | 0.9433 | 1.0218 | 0.3141 |
| TG(22:6_36:2) | 0.9902 | 1.0329 | 0.9463 | 0.9878 | 0.9978 | 1.3190 | 1.0853 | 1.0991 | 0.2360 |
| TG(22:6_38:1) | 0.9199 | 0.9508 | 0.8503 | 0.8955 | 1.3021 | 1.3338 | 1.2507 | 0.9865 | 0.1840 |
| TG(22:6_38:2) | 1.0111 | 0.9947 | 0.9362 | 0.9129 | 1.1013 | 1.3109 | 1.1265 | 1.0838 | 0.2044 |
Factors:
| F1 | Sample source:Brain | SEX:Female | Genotype:PS19 | Treatment:OIL |
| F2 | Sample source:Brain | SEX:Female | Genotype:PS19 | Treatment:TAMOXIFEN |
| F3 | Sample source:Brain | SEX:Female | Genotype:WT | Treatment:OIL |
| F4 | Sample source:Brain | SEX:Female | Genotype:WT | Treatment:TAMOXIFEN |
| F5 | Sample source:Brain | SEX:Male | Genotype:PS19 | Treatment:OIL |
| F6 | Sample source:Brain | SEX:Male | Genotype:PS19 | Treatment:TAMOXIFEN |
| F7 | Sample source:Brain | SEX:Male | Genotype:WT | Treatment:OIL |
| F8 | Sample source:Brain | SEX:Male | Genotype:WT | Treatment:TAMOXIFEN |
| F9 | Sample source:Brain | SEX:NA | Genotype:NA | Treatment:NA |
