Data for (Study ST004403)
(Analysis AN007361)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 1-Aminocyclopropanecarboxylic acid | 2.3007 | NA | 1.6802 | 0.0917 |
| 1-Methyl nicotinamide | 1.2703 | 0.0720 | 2.5638 | 0.4270 |
| 2,6-Diaminopimelic acid | 5.2241 | NA | 3.5610 | NA |
| 2-Amino-2-deoxy-D-mannose | 1.3178 | NA | 0.6822 | NA |
| 3-Aminoisobutanoic acid | 2.0155 | 0.0066 | 2.3026 | 0.0084 |
| 3-Dehydroxycarnitine | 3.6440 | 0.0267 | 0.5762 | 0.0848 |
| 4a-Carbinolamine tetrahydrobiopterin | 2.1285 | NA | 1.2501 | 0.2109 |
| 4-Guanidinobutanoic acid | 1.4835 | 0.0195 | 2.6001 | 0.1932 |
| 5-Amino-levulinic acid | 1.9097 | NA | 1.3105 | 0.4527 |
| 5^-Methylthioadenosine | 1.1114 | NA | 0.8886 | NA |
| 6-Hydroxydopamine | 1.1234 | 1.1255 | 0.7270 | 1.0362 |
| Acetylcholine | 2.8538 | 0.0105 | 0.4255 | 0.0506 |
| Acetyl-CoA | 1.1121 | NA | 0.8879 | NA |
| Adenine | 0.7875 | NA | 1.2125 | NA |
| Alanine | 2.0562 | 0.2593 | 1.7532 | 0.2597 |
| Allothreonine | 2.2864 | NA | 1.7177 | 0.0776 |
| alpha-Aminoadipic acid | 2.0645 | 0.0255 | 2.2024 | 0.0390 |
| Aminoisobutyric acid | 0.9335 | NA | 1.0665 | NA |
| Arginine | 3.7709 | NA | 2.6903 | NA |
| Argininosuccinic acid | 1.4310 | NA | 1.5318 | 0.0372 |
| Asparagine | 1.7097 | NA | 2.5938 | 0.0793 |
| beta-Alanine | 2.0530 | 0.2630 | 1.7505 | 0.2634 |
| Betaine | 0.9056 | 0.3879 | 1.4872 | 1.5157 |
| Biotin | 2.2354 | NA | 1.8213 | 0.0829 |
| CAR 2:0 | 2.3620 | 0.1627 | 1.5990 | 0.2087 |
| CAR DC5:0 | 2.0185 | 0.0343 | 2.2231 | 0.0547 |
| Carnitine | 2.0312 | NA | 2.3844 | NA |
| CDP-choline | 0.8602 | NA | 1.1398 | NA |
| Choline | -0.9122 | NA | -0.6090 | NA |
| Choline phosphate | 2.6085 | 0.0158 | 1.6859 | 0.0230 |
| cis-4-Hydroxy-D-proline | 1.9469 | NA | 1.2801 | 0.4558 |
| Citrulline | 2.4536 | NA | 0.9794 | 0.5348 |
| Creatine | 2.2167 | 0.0252 | 2.0377 | 0.0524 |
| Creatinine | 1.2626 | 0.3901 | 1.3432 | 1.2719 |
| Cys-Gly | 1.3825 | NA | 0.6175 | NA |
| Cystathionine | 1.3519 | 0.0252 | 2.5640 | 0.0589 |
| Cystine | -0.0340 | NA | -0.0788 | NA |
| Cytosine | 1.1937 | 0.4496 | 0.9898 | 1.6755 |
| D-Alanine | 2.0525 | 0.2635 | 1.7501 | 0.2639 |
| Dethiobiotin | 1.5634 | 0.3270 | 1.9271 | 0.4857 |
| Diethanolamine | 2.4603 | NA | 1.9273 | NA |
| Dihydrouracil | 1.0733 | NA | 0.9267 | NA |
| Dimethylarginine | 0.5797 | 0.4662 | 1.4180 | 1.8665 |
| D-Ornithine | 0.8429 | 0.7766 | 1.1547 | 1.5339 |
| Galactosamine | 1.3178 | NA | 0.6822 | NA |
| Glucosamine | 3.7355 | NA | 1.9151 | NA |
| Glutamine | 2.0725 | 0.7392 | 0.9155 | 0.6053 |
| Glutathione | 1.3388 | NA | 0.6612 | NA |
| Glycine | 2.3303 | NA | 1.8278 | 0.1163 |
| Guanidoacetic acid | 1.5674 | 0.2780 | 1.8829 | 0.6046 |
| Guanine | 2.4750 | NA | 1.9749 | NA |
| Homoserine | 2.2822 | NA | 1.7141 | 0.0814 |
| Hypotaurine | 3.0940 | 0.0157 | 0.8874 | 0.0030 |
| Hypoxanthine | 0.2132 | 0.9801 | 0.5002 | 2.6387 |
| Isoleucine | 2.3204 | NA | 1.8658 | NA |
| Kynurenine | 0.1725 | 0.2724 | 0.9047 | 2.9744 |
| Leucine | 3.0541 | NA | 2.4483 | NA |
| L-Homocysteine thiolactone | 1.1411 | 0.1818 | 0.2541 | 2.4231 |
| Lysine | 5.4473 | NA | 4.1421 | NA |
| Methionine | 2.2816 | NA | 1.8661 | NA |
| N(2)-Acetyllysine | 1.1234 | NA | 0.8766 | NA |
| N-6-Trimethyllysine | 1.4822 | 0.1345 | 2.0892 | 0.6226 |
| N-Acetylasparagine | 1.4813 | NA | 0.5187 | NA |
| N-Acetyl-D-galactosamine | 0.7387 | NA | 1.2613 | NA |
| N-Acetyl-D-glucosamine | 0.0362 | 0.2908 | NA | 2.3544 |
| N-Acetylneuraminic acid | 2.1103 | 0.3333 | 0.9081 | 0.9293 |
| N-Acetylserotonin | 0.1938 | NA | 1.8062 | NA |
| NAD+ | 1.1333 | NA | 0.8667 | NA |
| NADP+ | 1.1772 | NA | 1.1465 | 0.0287 |
| Niacinamide | -45.4333 | NA | -18.4387 | NA |
| Ophthalmic acid | 0.6700 | NA | 1.3300 | NA |
| Ornithine | 7.0377 | 0.3688 | 0.4364 | NA |
| Oxidized glutathione | 2.5158 | NA | 1.4606 | 0.0568 |
| Pantothenic acid | 0.8510 | NA | 0.7595 | 0.9043 |
| Phenylalanine | 2.2419 | 0.0019 | 1.7538 | 0.0024 |
| Phosphoethanolamine | 0.9206 | NA | 1.0794 | NA |
| Proline | 2.1461 | NA | 1.7428 | 0.0557 |
| Pyridoxal | 0.6528 | 0.8726 | 0.6483 | 2.1344 |
| Riboflavin | -0.5566 | NA | NA | NA |
| S-Adenosylhomocysteine | 0.8552 | NA | 1.1448 | NA |
| S-Adenosylmethionine | 0.7981 | NA | 1.2019 | NA |
| Sarcosine | 2.0526 | 0.2634 | 1.7502 | 0.2638 |
| Serine | 2.8076 | NA | 1.5942 | NA |
| Taurine | 2.0657 | NA | 2.1731 | 0.0548 |
| Thiamine | 1.9205 | NA | 1.9489 | NA |
| Threonine | 2.2822 | NA | 1.7141 | 0.0814 |
| Trigonelline | 0.7582 | 1.1978 | 0.7114 | 1.3133 |
| Tryptophan | 2.1384 | NA | 1.7032 | NA |
| Tyrosine | 1.8551 | NA | 1.3373 | 0.3052 |
| Valine | 1.8617 | NA | 1.5391 | 0.0636 |
Factors:
| F1 | Sample source:Male Homo sapien iPSCs derived neurons | Genotype:FXS | Sample type:Cultured cells |
| F2 | Sample source:Male Homo sapien iPSCs derived neurons | Genotype:FXS | Sample type:Extracellular media |
| F3 | Sample source:Male Homo sapien iPSCs derived neurons | Genotype:TD | Sample type:Cultured cells |
| F4 | Sample source:Male Homo sapien iPSCs derived neurons | Genotype:TD | Sample type:Extracellular media |
