Data for (Study ST004413)
(Analysis AN007380)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 |
|---|---|---|---|---|---|---|
| 1-4-beta-D-Xylan | 1.0698 | 0.9048 | 1.0235 | 1.0280 | 0.9603 | 1.0025 |
| 2/3-Phospho-D-glycerate | 0.8563 | 1.0413 | 1.0443 | 1.0485 | 0.9024 | 1.0878 |
| 2-Hydroxyglutarate/Citramalate | 1.0878 | 1.0969 | 0.9560 | 1.0567 | 0.7995 | 0.9803 |
| 2-Oxoglutaramate | 0.9846 | 1.0826 | 0.9417 | 0.9773 | 0.9143 | 1.1086 |
| 2-Oxoglutarate | 1.1134 | 1.1566 | 1.1705 | 1.0429 | 0.6757 | 0.8238 |
| 3-Phosphonooxypyruvate | 0.9184 | 1.1751 | 0.9110 | 1.1434 | 0.8538 | 0.9410 |
| 3-Sulfocatechol | 1.5884 | 1.1164 | 0.9090 | 0.7311 | 0.6736 | 1.0890 |
| 4-Acetamidobutanoate | 1.1977 | 0.8554 | 0.5814 | 1.0283 | 0.7680 | 1.5578 |
| 5-6-Dihydrothymine | 0.8533 | 1.0158 | 1.0570 | 1.0434 | 1.0374 | 0.9757 |
| (5-L-Glutamyl)-L-glutamine | 0.8663 | 1.0666 | 1.1839 | 1.0034 | 1.0282 | 0.8503 |
| 5-L-Glutamyl-taurine | 0.7257 | 1.0875 | 0.8351 | 1.1685 | 0.6311 | 1.4847 |
| Adenine | 0.8049 | 0.9150 | 1.0729 | 1.1591 | 1.3732 | 0.6113 |
| alpha-D-Ribose 1-phosphate | 0.4904 | 1.2102 | 1.1744 | 1.0280 | 0.6598 | 1.4259 |
| AMP | 0.0241 | 2.5996 | 0.1266 | 2.0583 | 0.1967 | 0.2458 |
| Ascorbate | 0.8112 | 0.9261 | 0.8682 | 0.8165 | 1.4381 | 1.2133 |
| Citrate | 1.1465 | 1.0360 | 1.0547 | 1.0158 | 0.8596 | 0.8811 |
| Cytidine | 0.6981 | 0.8307 | 1.0857 | 0.8690 | 1.1656 | 1.4033 |
| dAMP | 0.7536 | 1.5597 | 1.0169 | 1.0352 | 0.7197 | 0.9009 |
| D-Arabitol | 1.1899 | 1.0051 | 0.9298 | 0.9880 | 0.7424 | 1.1497 |
| dCMP | 0.8043 | 1.0745 | 1.0785 | 0.9705 | 1.1763 | 0.9077 |
| Dehydroascorbate | 1.1994 | 1.0243 | 1.0950 | 0.9874 | 0.8352 | 0.8637 |
| D-Glucose | 1.1136 | 0.8654 | 1.0175 | 0.9894 | 1.0000 | 1.0183 |
| D-Glyceraldehyde 3-phosphate/Glycerone phosphate | 0.8614 | 1.0269 | 1.1371 | 1.2642 | 0.8845 | 0.7202 |
| Diphosphate | 1.1602 | 1.1291 | 1.0907 | 1.0798 | 0.6839 | 0.8243 |
| D-Ribose | 1.0851 | 0.9603 | 1.0568 | 0.9888 | 0.8800 | 1.0335 |
| Ethanolamine phosphate | 0.8254 | 1.0441 | 1.0024 | 1.0174 | 0.9610 | 1.1428 |
| Fumarate | 1.0896 | 1.0750 | 1.0852 | 0.9985 | 0.8017 | 0.9507 |
| gamma-L-Glutamylputrescine | 0.7566 | 0.6699 | 1.1774 | 1.0407 | 0.7490 | 1.5902 |
| Glycerol 3-phosphate | 0.8030 | 1.1430 | 0.9117 | 1.0201 | 0.8281 | 1.2861 |
| Glycolate | 1.1037 | 0.9295 | 0.9273 | 1.0154 | 0.9039 | 1.1249 |
| Heptanoic acid | 0.9535 | 1.0434 | 1.0721 | 1.0186 | 0.8137 | 1.0911 |
| Hexanoic acid (caproate) | 1.1138 | 1.0201 | 1.0667 | 1.0155 | 0.7747 | 1.0030 |
| Hypoxanthine | 1.0200 | 0.6964 | 0.8868 | 1.0908 | 1.0107 | 1.3237 |
| Inosine | 0.7958 | 1.0602 | 1.4452 | 0.9043 | 0.9438 | 0.8890 |
| Lactate | 0.8829 | 1.1158 | 0.9769 | 1.0284 | 0.8716 | 1.1130 |
| L-Cysteate | 0.9509 | 1.0601 | 0.9803 | 1.0001 | 1.0753 | 0.9332 |
| L-Homoserine | 0.8638 | 0.8511 | 1.1903 | 0.8177 | 1.0127 | 1.3373 |
| Malate | 1.0689 | 1.0803 | 1.0743 | 1.0298 | 0.7521 | 0.9826 |
| Mannitol | 0.6653 | 1.2570 | 0.9558 | 1.0377 | 0.9460 | 1.1231 |
| N-Acetylneuraminate | 0.8397 | 0.9967 | 0.9328 | 0.9188 | 1.1399 | 1.2046 |
| N-Glycoloyl-neuraminate | 0.9509 | 1.1881 | 0.9120 | 1.1293 | 0.6452 | 1.1227 |
| N-Succinyl-L-glutamate 5-semialdehyde | 0.7705 | 1.1136 | 1.1405 | 0.8142 | 0.9239 | 1.3115 |
| Octanoic acid (caprylic acid) | 0.8282 | 0.8858 | 1.2556 | 1.0237 | 0.7621 | 1.2352 |
| Oxaloacetate | 0.9694 | 0.9222 | 1.0321 | 1.1599 | 0.8387 | 1.0137 |
| Pantetheine 4--phosphate | 0.5430 | 1.5247 | 0.8384 | 1.4011 | 0.4086 | 1.1237 |
| Pantothenol | 1.3072 | 0.6928 | 1.3398 | 0.5949 | 1.4672 | 0.7602 |
| Phosphate | 1.0875 | 1.0166 | 0.9648 | 1.0401 | 0.9229 | 0.9520 |
| Phosphoenolpyruvate | 0.8182 | 1.3192 | 0.8105 | 1.0887 | 0.5510 | 1.3770 |
| Pyruvate | 0.8891 | 1.1453 | 1.0262 | 0.9705 | 0.8650 | 1.1157 |
| (S)(+)-Allantoin | 1.3118 | 0.7984 | 1.0269 | 0.8948 | 1.0270 | 0.9833 |
| Sedoheptulose 1-phosphate | 1.0180 | 0.8949 | 0.6732 | 1.1816 | 0.7369 | 1.4228 |
| S-Glutathionyl-L-cysteine | 1.3745 | 0.6831 | 0.9394 | 0.8375 | 1.2110 | 1.0194 |
| sn-glycero-3-Phosphoethanolamine | 0.6854 | 0.7981 | 0.8003 | 0.8261 | 0.8844 | 2.0752 |
| Sphinganine 1-phosphate | 1.0130 | 1.1382 | 0.8947 | 1.0071 | 1.0083 | 0.9359 |
| Sphingosine 1-phosphate | 0.8365 | 1.2465 | 1.0239 | 1.0579 | 0.8689 | 0.9432 |
| Succinate | 1.0543 | 0.9591 | 0.9384 | 1.0591 | 0.9082 | 1.0573 |
| Taurine | 0.8866 | 1.1492 | 0.8686 | 1.0538 | 0.7509 | 1.2694 |
| Thymidine | 1.1537 | 0.9178 | 0.9408 | 1.0619 | 1.0051 | 0.8959 |
| Uracil | 0.8686 | 1.2754 | 0.9067 | 1.3052 | 0.5566 | 0.9655 |
| Urate | 0.9310 | 1.0388 | 0.9385 | 1.0770 | 0.8475 | 1.1364 |
Factors:
| F1 | Chromosome 21 status:Dp16-2xIfnrs | Sex:Female | Sample source:plasma |
| F2 | Chromosome 21 status:Dp16-2xIfnrs | Sex:Male | Sample source:plasma |
| F3 | Chromosome 21 status:Dp16 | Sex:Female | Sample source:plasma |
| F4 | Chromosome 21 status:Dp16 | Sex:Male | Sample source:plasma |
| F5 | Chromosome 21 status:WT | Sex:Female | Sample source:plasma |
| F6 | Chromosome 21 status:WT | Sex:Male | Sample source:plasma |
