Data for (Study ST004495)

(Analysis AN007537)

Values for each metabolite have been scaled by dividing by the mean across all factors

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Metabolite	F1	F2	F3	F4
11(E)-Eicosenoic Acid	0.9575	1.1586	0.7287	1.1552
(+/-)12(13)-DiHOME	0.8252	1.4571	0.7377	0.9800
12-Hydroxydodecanoic acid	0.9876	1.3366	0.8446	0.8313
1,5-Anhydro-D-glucitol	0.9923	1.5817	0.4396	0.9864
16-Hydroxyhexadecanoic acid	1.0564	1.1436	0.9611	0.8389
1-Methylhistidine	1.1509	1.9123	0.1724	0.7644
2,4-Dinitrophenol	0.6210	1.4854	0.8245	1.0691
2-Acetamido-N-β-aspartyl-2-deoxyhexopyranosylamine	1.1710	1.6405	0.3976	0.7909
2-Aminoadipic acid	0.8896	1.6042	0.3872	1.1190
2-Furoic acid	1.7486	1.1524	0.2844	0.8146
2-Methylbenzoic acid	1.0396	1.4087	0.5377	1.0140
2-Naphthalenesulfonic acid	0.8706	0.7103	0.9889	1.4302
2-Oxoglutaric acid	1.3479	1.3317	0.4313	0.8890
(2R)-2,3-Dihydroxypropanoic acid	1.3939	1.0413	0.3097	1.2550
3,4-Dihydroxybenzenesulfonic acid	1.9303	0.9139	0.0769	1.0789
3-Coumaric acid	0.9864	1.6572	0.3914	0.9651
3-Hydroxy-3-methylbutanoic acid	1.2884	1.0037	1.1062	0.6017
3-Hydroxy-3-methylglutaric acid	1.0654	1.5508	0.7155	0.6683
3-Hydroxybutyric acid	0.7874	2.3555	0.1491	0.7080
3-Indoxyl sulphate	0.8625	1.5885	0.2114	1.3376
3-Isopropylmalic acid	0.1458	0.1525	3.5499	0.1519
3-Phosphoglyceric acid	0.4502	2.5000	0.0616	0.9882
4-Dodecylbenzenesulfonic acid	0.7866	0.8784	1.0555	1.2795
4-Hydroxybenzaldehyde	0.9633	1.1716	0.9615	0.9036
4-Nitrophenol	0.7918	1.1177	0.8575	1.2331
4-Oxoproline	0.7759	1.9655	0.2789	0.9797
4-tert-Amylphenol	0.8260	1.0326	1.1276	1.0139
5-Aminolevulinic acid	0.9320	1.5289	0.2135	1.3255
5-Aminovaleric acid	0.8635	1.9474	0.3338	0.8553
5-Hydroxyindole-3-acetic acid	0.5032	0.8284	1.0129	1.6556
5^-S-Methyl-5^-thioadenosine	1.0156	1.8948	0.2359	0.8537
6-Phosphogluconic acid	0.2411	2.5494	0.2207	0.9888
8Z,11Z,14Z-Eicosatrienoic acid	0.5930	2.4146	0.5646	0.4278
Acamprosate	0.6998	0.9310	1.6901	0.6790
Adenine	1.0054	1.8905	0.2542	0.8498
Adenosine	1.0534	1.3936	0.2645	1.2884
Adenosine 3^5^-cyclic monophosphate	0.7331	1.2578	0.8138	1.1954
Adenosine 5^-monophosphate	1.7605	1.1864	0.3912	0.6620
Adenosine diphosphate (ADP)	0.7368	2.2257	0.3985	0.6390
Adenosine diphosphate ribose	1.3109	1.2940	0.5912	0.8040
Adenosine triphosphate (ATP)	0.2395	3.0610	0.3072	0.3923
Adipic acid	1.0017	0.6523	1.2477	1.0983
Adrenic acid	0.5831	2.2856	0.4543	0.6771
Arachidonic acid	0.9066	1.4376	0.7000	0.9558
Argininosuccinic acid	0.8426	1.6415	0.5411	0.9747
Ascorbic acid	1.0905	1.4345	0.8935	0.5815
Asparagine	0.8502	2.1222	0.2163	0.8113
Caprylic acid	0.9984	0.8356	1.0676	1.0983
Cholic acid	1.4059	0.5464	1.6713	0.3763
cis-4-Hydroxy-D-proline	0.6472	1.1781	1.2419	0.9328
cis-Aconitic acid	0.9456	1.8528	0.1712	1.0303
Citraconic acid	1.0738	0.7066	0.9635	1.2561
Citric acid	1.4522	0.6594	0.7694	1.1190
Creatine	1.0487	1.2142	0.8722	0.8649
Crotonic acid	0.6762	0.6318	1.5852	1.1068
Cyclic ADP-ribose	0.9490	1.5138	0.8802	0.6570
Cytidine	0.8967	1.4895	0.2512	1.3626
Decanoic acid	0.8298	0.7173	1.6278	0.8250
Deoxycholic Acid	2.7378	0.4407	0.0432	0.7784
D-(-)-Fructose	1.0712	1.5565	0.7118	0.6605
DL-3-Aminoisobutyric acid	1.0916	1.5407	0.3471	1.0206
DL-4-Hydroxyphenyllactic acid	0.5778	1.9828	0.3001	1.1393
DL-Arginine	0.6601	2.0939	0.2520	0.9939
DL-Malic acid	1.2138	2.3607	0.0182	0.4073
DL-Tryptophan	0.9724	1.4049	0.4278	1.1948
D-(-)-Lyxose	0.9514	1.7078	0.3260	1.0148
DL-β-Leucine	0.8984	1.8969	0.3251	0.8797
D-(-)-Mannitol	1.3519	1.1904	0.4352	1.0226
Docosahexaenoic acid	0.5667	2.2405	0.4291	0.7637
Dodecanedioic acid	2.3124	0.9427	0.2769	0.4680
Dodecyl sulfate	1.1817	0.4447	1.0460	1.3277
D-Sedoheptulose 7-phosphate	1.0959	1.3858	0.4378	1.0805
D-α-Hydroxyglutaric acid	0.7219	1.9062	0.4726	0.8993
Eicosapentaenoic acid	0.9870	1.4927	0.8929	0.6274
Flavin adenine dinucleotide (FAD)	0.7719	1.8941	0.6508	0.6833
Fructose-6-phosphate	1.0786	1.4806	0.5024	0.9384
Fumaric acid	1.2484	1.5834	0.1734	0.9948
Genistein	0.2226	0.0444	3.5233	0.2097
Gluconic acid	0.8784	1.5868	0.3746	1.1601
Glucose 6-phosphate	0.9448	1.5989	0.5566	0.8998
Glutamine	0.9570	1.7216	0.3175	1.0039
Glycerol 3-phosphate	1.1006	1.6702	0.3515	0.8776
Glycerophospho-N-palmitoyl ethanolamine	0.8456	2.0019	0.5308	0.6217
Glycine	0.8223	1.8758	0.2201	1.0818
Glycyl-L-leucine	0.8339	1.0579	1.4052	0.7030
Glyoxylic acid	1.2126	0.1645	1.7956	0.8273
Guanosine	0.9373	1.1604	0.7733	1.1290
Guanosine 5^-diphospho-D-mannose	0.9077	2.2546	0.3886	0.4491
Guanosine 5^-diphospho-ß-L-fucose	0.9618	2.1314	0.4398	0.4670
Guanosine monophosphate (GMP)	1.4714	1.4151	0.4734	0.6401
Heptanoic acid	0.8460	0.6234	1.2328	1.2977
Hippuric acid	0.3867	2.6733	0.3000	0.6399
Hydrocinnamic acid	0.8741	1.0694	1.1827	0.8737
Hypotaurine	1.6988	1.3305	0.4766	0.4941
Hypoxanthine	1.2597	1.0322	0.9756	0.7324
Inosine-5^-monophosphate (IMP)	1.0881	1.4971	0.8527	0.5620
Isobutyric acid	1.7328	0.7383	0.4026	1.1262
Itaconic acid	1.5135	1.4523	0.5893	0.4449
Lactic acid	0.9510	1.3423	0.7035	1.0031
L-Anserine	0.3537	0.4269	2.8116	0.4078
L-Ascorbic acid 2-sulfate	1.1749	1.3911	0.9032	0.5307
L-Aspartic acid	1.1367	1.4735	0.3105	1.0793
Lauric acid	0.9962	0.9261	1.1265	0.9512
L-Citrulline	0.5269	1.7292	0.3259	1.4180
L-Cysteinesulfinic acid	1.4830	0.6454	0.8432	1.0285
L-Glutamic acid	1.1002	1.5265	0.3570	1.0162
L-Glutathione oxidized	0.9817	1.6437	0.4842	0.8904
L-Glutathione (reduced)	0.3324	0.0209	3.5107	0.1360
L-Histidine	0.4846	2.7855	0.0178	0.7121
Linoleic acid	0.5339	1.6668	0.2877	1.5116
L-Phenylalanine	0.8409	1.7711	0.3939	0.9941
L-Serine	0.9737	1.6855	0.2638	1.0770
L-Threonic acid	0.8890	2.2317	0.3450	0.5343
L-Threonic acid-1,4-lactone	1.2471	0.4730	1.4690	0.8110
L-Tyrosine	0.9607	1.6593	0.4096	0.9704
Maleic acid	0.9644	0.7983	1.2609	0.9764
Malonic acid	0.4613	2.5983	0.2474	0.6931
Mesaconic acid	0.5762	1.3407	1.0906	0.9926
Methylmalonic acid	1.0270	1.6049	0.5112	0.8569
Monobutyl phthalate	1.2090	0.9834	0.9249	0.8827
Myristic acid	0.9505	1.1076	0.9609	0.9810
Myristyl sulfate	1.3954	0.5302	1.1284	0.9460
N-Acetylaspartic acid	0.8214	1.9743	0.0579	1.1464
N-Acetyl-D-galactosamine 4-sulfate	0.2184	1.9295	0.0151	1.8370
N-Acetylglycine	1.1053	0.9339	0.6616	1.2991
N-Acetyl-L-methionine	0.8507	1.5312	0.3505	1.2676
N-Acetylornithine	0.8506	1.6897	0.5721	0.8877
N-Acetyl-α-D-glucosamine 1-phosphate	1.1418	1.5511	0.3875	0.9196
N-Arachidonoyl taurine	1.3773	1.4416	0.4552	0.7258
N-Ethylglycine	1.1290	1.3180	0.6554	0.8976
N-Formylmethionine	0.7258	0.6532	1.6057	1.0153
N-Glycolylneuraminic acid	0.5729	1.5574	0.3533	1.5164
Nicotinamide adenine dinucleotide	0.9691	1.4934	0.8813	0.6562
Nicotinamide adenine dinucleotide phosphate	0.6435	2.4419	0.4440	0.4706
Nonanoic acid	0.9691	0.8919	1.1718	0.9672
N-α-Acetyl-L-asparagine	1.1899	1.4264	0.2348	1.1489
O-Phosphorylethanolamine	0.8722	1.4090	0.4888	1.2301
Ornithine	0.5453	1.7489	0.3113	1.3945
Orotidine	1.7673	1.0787	0.2648	0.8891
Palmitic Acid	1.0338	0.8317	1.1413	0.9932
Palmitoleic Acid	0.6914	1.9031	0.4355	0.9700
Pantothenic acid	1.0807	1.6425	0.5304	0.7465
Pentadecanoic acid	0.8778	1.0325	1.0650	1.0247
Perillic acid	1.2701	1.6397	0.2654	0.8248
PG(18:2(9Z,12Z)/0:0)	0.5559	1.6898	0.3663	1.3881
Phosphocreatine	0.6684	1.7856	0.3270	1.2190
Pseudouridine	1.0202	1.7186	0.3695	0.8916
Pyrrole-2-carboxylic acid	1.4203	1.3356	0.3478	0.8962
Pyruvic acid	0.9596	1.2254	0.7368	1.0782
Ribose 5-phosphate	0.7880	1.1200	0.6298	1.4621
Salicylic acid	1.4048	0.3226	0.7927	1.4799
Stearic acid	1.0737	0.7479	1.0916	1.0868
Succinic acid	0.6710	2.3436	0.4092	0.5763
Succinic semialdehyde	0.7708	2.0645	0.2916	0.8731
Taurine	1.2131	1.1805	0.6827	0.9236
Threonine	0.8423	1.7899	0.3004	1.0674
Thymidine	0.9028	1.6679	0.2691	1.1603
Tridecylic acid	0.8081	0.9445	1.4026	0.8448
UDP-N-acetylglucosamine	0.8989	1.9678	0.3628	0.7705
Undecanoic acid	0.7020	0.9312	1.5501	0.8167
Uracil	1.1252	1.5944	0.5554	0.7251
Uric acid	0.8476	0.7991	0.9889	1.3644
Uridine	1.4433	1.3049	0.3283	0.9235
Uridine 5^-diphosphate (UDP)	0.5438	2.3931	0.4593	0.6038
Uridine 5^-diphosphoglucuronic acid	0.4221	2.7504	0.3466	0.4809
Uridine monophosphate (UMP)	2.0302	0.9414	0.2350	0.7934
Valeric acid	0.9914	1.1322	0.8279	1.0485
Vanillin	1.1605	0.8406	1.0333	0.9656
Xanthine	0.9300	1.1785	0.9482	0.9433
Xanthosine	0.7181	1.3832	1.0789	0.8197
Xylitol	1.0229	1.8226	0.3005	0.8540
Xylulose 5-phosphate	0.7882	1.6645	0.4289	1.1184
α-D-Glucose-1,6-bisphosphate	0.5587	2.0392	0.3931	1.0091
α-Linolenic acid	0.5250	1.7343	0.3811	1.3596
β-Alanine	1.0807	1.3304	0.6752	0.9136
β-D-Glucopyranuronic acid	0.7279	1.7639	0.7162	0.7920
δ-Gluconic acid δ-lactone	0.8842	1.3252	0.9190	0.8716
Υ-Aminobutyric acid (GABA)	1.0176	1.3172	0.9901	0.6751

Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study

Factors:

F1	Genotype:TIGAR-knockout | Treatment:Control | Sample source:colon
F2	Genotype:TIGAR-knockout | Treatment:DSS | Sample source:colon
F3	Genotype:Wild-type | Treatment:Control | Sample source:colon
F4	Genotype:Wild-type | Treatment:DSS | Sample source:colon