Data for (Study ST000154)
(Analysis AN000245)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 |
|---|---|---|---|---|---|---|---|---|---|
| 2 or 3-phosphoglycerate_13C_1 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 2 or 3-phosphoglycerate_13C_2 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 2 or 3-phosphoglycerate_13C_3 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 2 or 3-phosphoglycerate_2PG/3PG | 0.2202 | 1.5230 | 1.2763 | 0.2415 | 0.2596 | 0.1505 | 0.2013 | 1.8010 | 3.0434 |
| 3-Glycerophosphate | 0.6768 | 0.7606 | 0.5202 | 0.0812 | 0.0239 | 0.0010 | 1.2425 | 2.3880 | 3.3060 |
| 3-Glycerophosphate_13C_1 | 2.7069 | 0.0192 | 0.0164 | 0.4897 | 0.0260 | 0.0037 | 4.3198 | 0.0507 | 0.0583 |
| 3-Glycerophosphate_13C_2 | 2.9213 | 0.0128 | 0.0230 | 0.5374 | 0.0475 | 0.0438 | 5.0662 | 0.0086 | 0.0103 |
| 3-Glycerophosphate_13C_3 | 0.9859 | NA | NA | NA | NA | NA | 1.0141 | NA | NA |
| 3-phosphoglyceraldehyde | NA | 0.8144 | 0.4878 | 0.3872 | NA | NA | NA | 1.2422 | 1.4273 |
| 3-phosphoglyceraldehyde_13C_1 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 3-phosphoglyceraldehyde_13C_2 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 3-phosphoglyceraldehyde_13C_3 | 0.4746 | 0.3433 | NA | 0.3275 | NA | NA | NA | 1.5210 | 2.3256 |
| 6-Phosphogluconate | 0.8377 | 2.0052 | 1.7634 | 0.3752 | 0.4000 | 0.6684 | 0.5716 | 0.8039 | 1.5746 |
| 6-Phosphogluconate_13C_1 | NA | NA | NA | NA | NA | 1.0000 | NA | NA | NA |
| 6-Phosphogluconate_13C_2 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 6-Phosphogluconate_13C_3 | 0.7247 | NA | 2.4221 | NA | NA | NA | 0.4392 | NA | 1.5254 |
| 6-Phosphogluconate_13C_4 | 0.7247 | NA | 2.4221 | NA | NA | NA | 0.4392 | NA | 1.5254 |
| 6-Phosphogluconate_13C_5 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| 6-Phosphogluconate_13C_6 | 1.0041 | NA | 1.1856 | NA | NA | NA | 0.8059 | NA | 1.1901 |
| Acetyl-CoA | 0.8337 | 1.6771 | 1.0890 | 0.6279 | 0.7018 | 0.7802 | 0.4268 | 1.7626 | 1.1010 |
| Acetyl-CoA_13C_1 | 0.9229 | 1.6910 | 0.0958 | 0.6291 | 1.4919 | 0.1016 | 1.0336 | 1.9258 | 0.2080 |
| Acetyl-CoA_13C_2 | 0.7004 | 0.3159 | 2.0123 | 0.2100 | 0.4598 | 1.7186 | 0.5312 | 0.2979 | 2.7539 |
| Adenosine diphosphate | 3.3450 | 0.4431 | 0.2456 | 1.2242 | 0.3115 | 0.3533 | 1.7610 | 0.7058 | 0.6104 |
| Adenosine diphosphate_13C_1 | 2.8689 | 0.3337 | 0.0523 | 0.9862 | 0.5369 | 0.0462 | 3.5065 | 0.5850 | 0.0843 |
| Adenosine diphosphate_13C_2 | 2.3554 | 0.1342 | 0.7238 | 0.6341 | 0.2497 | 1.0132 | 2.1532 | 0.1703 | 1.5662 |
| Adenosine diphosphate_13C_3 | 3.2727 | 0.0626 | 0.0628 | 1.1339 | 0.0300 | 0.0409 | 4.2558 | 0.0353 | 0.1060 |
| Adenosine diphosphate_13C_4 | 1.9305 | NA | 0.0108 | 0.4279 | NA | NA | 1.6297 | NA | 0.0124 |
| Adenosine diphosphate_13C_5 | 1.7292 | NA | NA | 0.6629 | NA | NA | 0.6079 | NA | NA |
| Adenosine monophosphate | 3.8829 | 0.3861 | 0.2269 | 0.9621 | 0.3668 | 0.3348 | 1.9368 | 0.5821 | 0.3215 |
| Adenosine monophosphate_13C_1 | 3.3959 | 0.2564 | 0.0222 | 0.6415 | 0.3849 | 0.0362 | 3.7721 | 0.4462 | 0.0445 |
| Adenosine monophosphate_13C_2 | 3.2857 | 0.1170 | 0.5419 | 0.5106 | 0.1662 | 0.6742 | 2.6847 | 0.1521 | 0.8675 |
| Adenosine monophosphate_13C_3 | 3.4883 | 0.0079 | 0.0197 | 0.8610 | 0.0313 | 0.0335 | 4.1914 | 0.0096 | 0.0305 |
| Adenosine monophosphate_13C_4 | 3.4073 | 0.0027 | 0.0022 | 0.3919 | 0.0012 | 0.0111 | 2.5147 | NA | 0.0072 |
| Adenosine monophosphate_13C_5 | 2.3451 | 0.0562 | NA | 0.4093 | NA | NA | 0.8735 | NA | 0.0600 |
| Adenosine triphosphate | 1.4772 | 1.1276 | 0.7358 | 0.5757 | 0.8875 | 0.5461 | 0.7052 | 1.5050 | 1.4399 |
| Adenosine triphosphate_13C_1 | 1.4843 | 1.1895 | 0.1874 | 0.5760 | 1.7052 | 0.1821 | 1.6824 | 1.7200 | 0.2730 |
| Adenosine triphosphate_13C_2 | 0.7393 | 0.3149 | 1.7340 | 0.2252 | 0.4396 | 1.6365 | 0.5759 | 0.3388 | 2.9959 |
| Adenosine triphosphate_13C_3 | 2.9316 | 0.1128 | 0.2128 | 1.1699 | 0.2378 | 0.1415 | 3.3819 | 0.1022 | 0.4104 |
| Adenosine triphosphate_13C_4 | 2.4252 | 0.0350 | 0.0947 | 0.5928 | NA | 0.0337 | 1.8472 | NA | 0.1035 |
| Adenosine triphosphate_13C_5 | 2.0052 | NA | NA | 0.6568 | NA | NA | 0.6389 | 0.0974 | NA |
| Aspartate | 1.4919 | 1.5619 | 3.3844 | 0.7439 | 0.0859 | 0.0950 | 0.5601 | 0.5884 | 0.9816 |
| Aspartate_13C_1 | 0.6469 | 3.5305 | 0.0687 | 0.3290 | 3.5124 | 0.0611 | 0.2241 | 1.1782 | 0.0280 |
| Aspartate_13C_2 | 3.6670 | 0.4291 | 0.0481 | 2.0153 | 0.0954 | 0.0675 | 1.2761 | 0.1257 | 0.0010 |
| Aspartate_13C_3 | 3.2162 | 2.0328 | 0.1259 | 1.2967 | 0.1514 | 0.1441 | 1.2801 | 0.2329 | 0.3171 |
| Aspartate_13C_4 | 0.7795 | NA | NA | 0.5324 | NA | NA | 0.2543 | NA | 5.3014 |
| Citrate or Isocitrate | 0.4087 | 2.2026 | 1.7853 | 0.3940 | 0.1288 | 0.1315 | 0.3769 | 1.4676 | 2.1046 |
| Citrate or Isocitrate_13C_1 | 1.9137 | 0.0366 | 0.0897 | 1.8509 | 0.3232 | NA | 2.1522 | 0.0494 | 0.0495 |
| Citrate or Isocitrate_13C_2 | 1.7234 | NA | NA | 3.1118 | 0.0235 | 0.0197 | 1.5295 | NA | NA |
| Citrate or Isocitrate_13C_3 | 2.5735 | 0.0792 | 0.0794 | 2.1450 | 0.3579 | 0.3241 | 2.7970 | 0.1180 | 0.2937 |
| Citrate or Isocitrate_13C_4 | 1.5831 | 0.1667 | NA | 0.9866 | NA | NA | 1.5338 | 0.3546 | 0.0015 |
| Citrate or Isocitrate_13C_5 | 1.2175 | NA | NA | 0.5715 | NA | NA | 1.0682 | NA | NA |
| Citrate or Isocitrate_13C_6 | 1.1529 | 0.9674 | NA | 1.1951 | NA | NA | 0.7804 | NA | 0.6474 |
| Erythrose 4-phosphate | 0.3172 | 1.8064 | 1.3717 | 0.2699 | 0.3688 | 0.7541 | 0.3898 | 1.7907 | 1.9314 |
| Erythrose 4-phosphate_13C_1 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Erythrose 4-phosphate_13C_2 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Erythrose 4-phosphate_13C_3 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Erythrose 4-phosphate_13C_4 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Fructose 1,6-bisphosphate | 0.1456 | 0.6816 | 0.6255 | 0.1754 | 0.4758 | 0.3697 | 0.1070 | 2.3507 | 4.0687 |
| Fructose 1,6-bisphosphate_13C_1 | 0.2720 | 0.2360 | NA | 0.3345 | 2.8978 | 1.3033 | 0.4281 | 0.2289 | 1.4388 |
| Fructose 1,6-bisphosphate_13C_2 | 1.1272 | 0.9327 | 1.0903 | 1.7073 | 0.1803 | 0.1326 | 1.9788 | 0.7492 | 0.8251 |
| Fructose 1,6-bisphosphate_13C_3 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Fructose 1,6-bisphosphate_13C_4 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Fructose 1,6-bisphosphate_13C_5 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Fructose 1,6-bisphosphate_13C_6 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Glucose 6-phosphate or fructose-6-phosphate | 0.3978 | 1.0672 | 0.8506 | 0.1875 | 0.1289 | 0.1426 | 0.2627 | 2.0313 | 3.6410 |
| Glucose 6-phosphate or fructose-6-phosphate_13C_1 | 0.4906 | 0.3447 | 0.9892 | 0.6308 | 1.6517 | 1.8206 | 1.9340 | 0.1646 | 0.6772 |
| Glucose 6-phosphate or fructose-6-phosphate_13C_2 | 2.0583 | 0.0556 | 0.0877 | 0.8676 | 0.0557 | 0.0723 | 3.8518 | 0.0270 | 0.0377 |
| Glucose 6-phosphate or fructose-6-phosphate_13C_3 | 0.1402 | NA | NA | 0.1047 | NA | NA | 1.8717 | NA | NA |
| Glucose 6-phosphate or fructose-6-phosphate_13C_4 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Glucose 6-phosphate or fructose-6-phosphate_13C_5 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Glucose 6-phosphate or fructose-6-phosphate_13C_6 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Glutamate | 1.6386 | 0.7299 | 1.6321 | 0.5784 | 0.1349 | 0.0888 | 1.5810 | 0.7957 | 1.7276 |
| Glutamate_13C_1 | 0.2044 | 1.9295 | 0.0002 | 0.0607 | 1.9367 | NA | 0.2970 | 1.9049 | NA |
| Glutamate_13C_2 | 2.4184 | 0.0273 | 0.0232 | 0.8703 | 0.0398 | 0.0111 | 2.9634 | 0.0265 | NA |
| Glutamate_13C_3 | 2.0195 | NA | 0.0026 | 0.6864 | NA | 0.0055 | 2.8452 | NA | 0.0044 |
| Glutamate_13C_4 | 1.6247 | 0.0031 | 0.0013 | 0.5532 | 0.0038 | NA | 2.1526 | 0.0003 | NA |
| Glutamate_13C_5 | 1.1530 | NA | NA | 0.3678 | 0.0045 | NA | 1.6003 | NA | NA |
| Lactate | 0.6637 | 1.2293 | 1.0452 | 0.5531 | NA | NA | 0.4984 | 1.5266 | 1.2009 |
| Lactate_13C_1 | 2.2216 | 0.2779 | 0.1598 | 1.2310 | NA | NA | 1.0933 | 0.3332 | 0.8719 |
| Lactate_13C_2 | 1.3626 | NA | NA | 0.8925 | NA | NA | 1.0050 | NA | 0.0047 |
| Lactate_13C_3 | 1.6270 | NA | NA | 0.4753 | NA | NA | 0.3219 | NA | NA |
| Malate | 0.8024 | 1.8369 | 1.3547 | 0.8691 | 0.1023 | 0.0250 | 0.7334 | 1.0449 | 1.3077 |
| Malate_13C_1 | 2.4239 | 0.0033 | 0.1347 | 2.0047 | 0.0836 | 0.2214 | 2.7471 | 0.0340 | 0.0412 |
| Malate_13C_2 | 2.5293 | 0.0053 | 0.0470 | 2.9169 | 0.1257 | 0.0719 | 2.6245 | 0.0077 | 0.0114 |
| Malate_13C_3 | 2.1487 | 0.0099 | NA | 0.8510 | 0.0192 | 0.0235 | 2.2921 | NA | NA |
| Malate_13C_4 | 1.0968 | NA | 0.0362 | 1.2667 | NA | NA | 1.2539 | NA | 0.1116 |
| Malonyl-CoA | 0.7841 | 1.7463 | 1.0902 | 0.2451 | 0.3619 | 0.4381 | 1.5716 | 1.5979 | 1.1648 |
| Malonyl-CoA_13C_1 | 1.0176 | 1.8766 | 0.1235 | 0.3395 | 1.0166 | NA | 0.9432 | 1.7959 | 0.0337 |
| Malonyl-CoA_13C_2 | 0.4518 | 0.0960 | 1.9393 | 3.1754 | 0.0665 | 0.7124 | 0.1271 | 0.1765 | 2.7057 |
| Malonyl-CoA_13C_3 | 0.7739 | 3.5983 | 0.3501 | 0.1698 | NA | 0.1138 | 0.4264 | 2.0857 | NA |
| Nicotinamide Adenine Dinucleotide oxidized | 0.3904 | 1.8020 | 0.7096 | 0.3250 | 1.2494 | 0.9360 | 0.2476 | 2.6531 | 0.6869 |
| Nicotinamide Adenine Dinucleotide oxidized_13C_1 | 0.7774 | 1.4701 | 0.7092 | 0.5105 | 1.1539 | 0.1917 | 0.6093 | 2.3794 | 1.1987 |
| Nicotinamide Adenine Dinucleotide oxidized_13C_2 | 1.1212 | 0.5297 | 1.4311 | 0.5865 | 0.4107 | 1.6147 | 1.0347 | 0.7394 | 1.5320 |
| Nicotinamide Adenine Dinucleotide oxidized_13C_3 | 1.5366 | 0.0367 | 1.5408 | 0.4507 | 0.0552 | 0.0743 | 1.5811 | 0.0586 | 3.6659 |
| Nicotinamide Adenine Dinucleotide oxidized_13C_4 | 3.6356 | 0.0162 | 0.0593 | 1.2894 | 0.0082 | 0.0083 | 3.4839 | 0.0063 | 0.1617 |
| Nicotinamide Adenine Dinucleotide oxidized_13C_5 | 2.2013 | NA | 0.0267 | 0.7046 | NA | NA | 2.3836 | 0.0082 | 0.0143 |
| Nicotinamide Adenine Dinucleotide reduced | 0.2141 | 1.7448 | 0.7598 | 0.1164 | 1.2264 | 0.8179 | 0.2704 | 2.9501 | 0.9001 |
| Nicotinamide Adenine Dinucleotide reduced_13C_1 | 0.4132 | 1.3796 | 0.6966 | 0.2184 | 1.0667 | 0.2103 | 0.6227 | 2.5965 | 1.5328 |
| Nicotinamide Adenine Dinucleotide reduced_13C_2 | 0.6252 | 0.5134 | 1.5035 | 0.2565 | 0.4367 | 1.5872 | 1.1387 | 0.8238 | 2.1149 |
| Nicotinamide Adenine Dinucleotide reduced_13C_3 | 0.7892 | 0.0549 | 1.4895 | 0.3022 | 0.0525 | 0.0598 | 1.5659 | 0.0603 | 4.6256 |
| Nicotinamide Adenine Dinucleotide reduced_13C_4 | 2.3623 | 0.0103 | 0.0981 | 0.7582 | 0.0147 | 0.0194 | 4.5419 | 0.0035 | 0.1988 |
| Nicotinamide Adenine Dinucleotide reduced_13C_5 | 1.9669 | 0.0126 | 0.0255 | 0.5761 | NA | 0.0038 | 4.3699 | 0.0029 | 0.0455 |
| Phosphoenolpyruvate | 0.2488 | 1.3570 | 1.3992 | 0.4133 | 0.2447 | 0.3578 | NA | 1.2417 | 1.6102 |
| Phosphoenolpyruvate_13C_1 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Phosphoenolpyruvate_13C_2 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Phosphoenolpyruvate_13C_3 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Ribose-5-phosphate or xylulose 5-phosphate | 0.0509 | 0.7625 | 0.4258 | 0.0525 | 0.2913 | 0.2022 | 0.0581 | 3.0578 | 3.1527 |
| Ribose-5-phosphate or xylulose 5-phosphate_13C_1 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Ribose-5-phosphate or xylulose 5-phosphate_13C_2 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Ribose-5-phosphate or xylulose 5-phosphate_13C_3 | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA |
| Ribose-5-phosphate or xylulose 5-phosphate_13C_4 | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA |
| Ribose-5-phosphate or xylulose 5-phosphate_13C_5 | NA | NA | NA | NA | NA | NA | 1.0000 | NA | NA |
| Sedoheptulose 7-phosphate | 0.3381 | 0.4603 | 0.3669 | 0.0933 | 0.1064 | 0.1280 | 1.3192 | 2.3791 | 3.8087 |
| Sedoheptulose 7-phosphate_13C_1 | 0.5035 | NA | NA | NA | NA | NA | 2.4118 | NA | 0.0847 |
| Sedoheptulose 7-phosphate_13C_2 | 0.5235 | NA | NA | 0.1302 | NA | NA | 2.3463 | NA | NA |
| Sedoheptulose 7-phosphate_13C_3 | 0.5965 | 0.0013 | NA | 0.1272 | NA | NA | 2.3603 | NA | NA |
| Sedoheptulose 7-phosphate_13C_4 | 0.6034 | 0.0007 | NA | 0.2253 | NA | NA | 2.3211 | NA | NA |
| Sedoheptulose 7-phosphate_13C_5 | 0.3439 | 0.4530 | NA | NA | NA | NA | 2.0208 | NA | NA |
| Sedoheptulose 7-phosphate_13C_6 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Sedoheptulose 7-phosphate_13C_7 | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Sucrose | 1.2831 | 1.1201 | 1.0345 | 2.5391 | 0.0667 | 0.0388 | 1.4501 | 0.6075 | 0.8600 |
| Sucrose_13C_1 | 1.8554 | 0.0380 | 0.0645 | 2.2510 | 0.1391 | 0.2427 | 2.2083 | 0.0012 | 0.0218 |
| Sucrose_13C_2 | NA | NA | NA | 1.0000 | NA | NA | NA | NA | NA |
| Sucrose_13C_3 | 0.2574 | NA | NA | 1.1617 | NA | NA | 1.1397 | NA | NA |
| Sucrose_13C_4 | NA | 1.6274 | 0.9086 | NA | NA | NA | 0.4640 | NA | NA |
Factors:
| F1 | Type:Noxa high clone | Treatment:13C labeled glucose |
| F2 | Type:Noxa high clone | Treatment:15N alpha nitrogen labeled glutamine |
| F3 | Type:Noxa high clone | Treatment:15N amide nitrogen labeled glutamine |
| F4 | Type:Noxa high plasmid | Treatment:13C labeled glucose |
| F5 | Type:Noxa high plasmid | Treatment:15N alpha nitrogen labeled glutamine |
| F6 | Type:Noxa high plasmid | Treatment:15N amide nitrogen labeled glutamine |
| F7 | Type:Noxa low clone | Treatment:13C labeled glucose |
| F8 | Type:Noxa low clone | Treatment:15N alpha nitrogen labeled glutamine |
| F9 | Type:Noxa low clone | Treatment:15N amide nitrogen labeled glutamine |
