Data for Metabolomics of aged iPSC (Study ST000554)
(Analysis AN000850)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 |
|---|---|---|---|
| 2^,4^-DIHYDROXYACETOPHENONE | 0.9596 | 1.0616 | 1.0038 |
| 2^-DEOXYCYTIDINE 5^-MONOPHOSPHATE | 1.3130 | 1.6790 | 0.7390 |
| 3-HYDROXY-3-METHYLGLUTARATE | 1.0779 | 1.6705 | 0.8347 |
| 3-Hydroxydecanoic acid | 0.8188 | 0.9718 | 1.0781 |
| 3-METHYL-2-OXOVALERIC ACID | 0.6139 | 1.5357 | 1.0473 |
| 3-methyladipic acid | 0.8112 | 0.6117 | 1.1532 |
| 3-SULFINO-L-ALANINE | 1.1275 | 0.9842 | 0.9522 |
| 3-tert-Butyladipic acid | 0.9801 | 1.1353 | 0.9809 |
| 4-HYDROXYBENZALDEHYDE | 0.9262 | 0.8966 | 1.0502 |
| 4-METHYL-2-OXO-PENTANOIC ACID_R1 | 0.6432 | 1.4913 | 1.0445 |
| 4-METHYL-2-OXO-PENTANOIC ACID_R2 | 0.6610 | 1.4606 | 1.0435 |
| 4-oxoproline | 0.9298 | 1.4311 | 0.9419 |
| 5-AMINOLEVULINIC ACID | 0.6072 | 1.4316 | 1.0708 |
| ADENINE | 0.8485 | 0.7959 | 1.1014 |
| ADENOSINE 5^-MONOPHOSPHATE | 0.9265 | 0.7869 | 1.0720 |
| ADP | 0.9255 | 1.3702 | 0.9558 |
| Arachidonic Acid (20:4) | 0.3474 | 0.2246 | 1.4161 |
| ASPARAGINE | 0.9254 | 0.8236 | 1.0651 |
| ASPARTATE | 1.0239 | 1.4340 | 0.9036 |
| BOC-L-Tyrosine_R1 | 0.9157 | 1.0981 | 1.0141 |
| BOC-L-Tyrosine_R2 | 0.8894 | 1.1184 | 1.0206 |
| C6H12O6-HEXOSE/KETOSE/INOSITOL | 1.1884 | 1.2770 | 0.8693 |
| Caffeic Acid | 0.9308 | 0.9734 | 1.0330 |
| CITRATE | 0.6374 | 1.1786 | 1.1093 |
| CITRIC ACID-13C6 | 1.0973 | 1.2435 | 0.9124 |
| CMP_R1 | 1.1411 | 1.7548 | 0.7926 |
| CMP_R2 | 0.7979 | 2.7694 | 0.7270 |
| CREATINE | 0.8623 | 1.9220 | 0.8707 |
| CYS-GLY | 1.0303 | 2.1229 | 0.7370 |
| CYTIDINE | 0.9727 | 0.6208 | 1.0868 |
| DEOXYCYTIDINE | 1.4264 | 0.9022 | 0.8490 |
| D-GLUCURONIC ACID/D-GLUCURONOLACTONE/D-(+)-GALACTURONIC ACID | 1.1125 | 1.8305 | 0.7889 |
| DIHYDROXYACETONE PHOSPHATE | 1.0973 | 0.3616 | 1.0888 |
| Dinoterb (herbicide) | 0.8260 | 1.1057 | 1.0485 |
| Docosahexaenoic Acid (22:6) | 0.3859 | 0.2495 | 1.3957 |
| D-RIBOSE 5-PHOSPHATE/RIBULOSE 5-PHOSPHATE | 1.3368 | 0.8901 | 0.8872 |
| Fumaric Acid | 0.7327 | 2.3794 | 0.8310 |
| GLUCONIC ACID/D-GULONIC ACID GAMA-LACTONE | 1.1888 | 1.5193 | 0.8206 |
| GLUCOSE/FRUCTOSE_R1 | 1.1357 | 1.2132 | 0.9031 |
| GLUCOSE/FRUCTOSE_R2 | 1.1118 | 1.2301 | 0.9093 |
| GLUTATHIONE | 0.8328 | 1.4099 | 0.9849 |
| Glyceraldehyde | 0.8036 | 1.5982 | 0.9589 |
| GLYCERALDEHYDE/LACTATE | 0.5744 | 0.8853 | 1.1932 |
| GLYCERIC ACID | 0.4920 | 2.3418 | 0.9349 |
| GUANINE | 2.0379 | 0.1486 | 0.7551 |
| Guanosine | 1.3745 | 1.1996 | 0.8103 |
| HYPOXANTHINE | 0.8902 | 1.3971 | 0.9645 |
| INOSINE | 0.9817 | 1.5605 | 0.8952 |
| ISOCITRIC ACID | 0.4531 | 0.8342 | 1.2519 |
| L-2-PHOSPHOGLYCERIC ACID | 0.8139 | 1.3230 | 1.0098 |
| L-ARGININE | 0.7387 | 0.5827 | 1.1880 |
| L-CYSTATHIONINE | 1.1432 | 1.8183 | 0.7791 |
| L-CYSTEINE | 0.9752 | 0.8663 | 1.0367 |
| L-GLUTAMIC ACID | 1.0333 | 1.3674 | 0.9132 |
| L-GLUTAMINE | 0.8751 | 1.3305 | 0.9838 |
| L-HISTIDINE | 0.9371 | 0.8974 | 1.0457 |
| Linoleic Acid (18:2) | 0.4468 | 0.3806 | 1.3451 |
| L-ISOLEUCINE_R1 | 0.8080 | 1.0760 | 1.0616 |
| L-ISOLEUCINE_R2 | 0.7544 | 1.1204 | 1.0742 |
| LL-2,6-DIAMINOHEPTANEDIOATE | 1.0847 | 1.4760 | 0.8709 |
| L-METHIONINE | 0.6859 | 1.0024 | 1.1251 |
| L-Tryptophan-13C11 | 0.9197 | 0.8295 | 1.0662 |
| L-TYROSINE | 0.7146 | 0.9109 | 1.1320 |
| L-VALINE | 0.7381 | 1.0632 | 1.0921 |
| LysoPC (18:1) | 0.7363 | 1.0971 | 1.0861 |
| LysoPE (16:0) | 0.3533 | 0.1301 | 1.4326 |
| LysoPE (18:0) | 0.3548 | 0.1226 | 1.4336 |
| LysoPE (18:1)_R1 | 0.5754 | 0.3626 | 1.2973 |
| LysoPE (18:1)_R2 | 0.4715 | 0.2586 | 1.3597 |
| LysoPE (20:4)_R1 | 0.6223 | 0.2848 | 1.2941 |
| LysoPE (20:4)_R2 | 1.3341 | 0.3845 | 0.9894 |
| LysoPE (22:6) | 0.5448 | 0.3404 | 1.3140 |
| MALATE | 0.7912 | 1.6829 | 0.9469 |
| Mannitol | 0.8655 | 2.1697 | 0.8199 |
| Mono-(2-Ethylhexyl) Phthalate Dimer | 0.4753 | 0.2896 | 1.3520 |
| Monobutyl phthalate | 0.7856 | 0.4714 | 1.1915 |
| N-Acetylaspartylglutamic acid | 3.0948 | 0.1256 | 0.3369 |
| N-ACETYL-DL-GLUTAMIC ACID_R1 | 1.3202 | 0.3930 | 0.9933 |
| N-ACETYL-DL-GLUTAMIC ACID_R2 | 1.8954 | 0.1928 | 0.8033 |
| N-ACETYL-D-MANNOSAMINE | 0.9900 | 1.8130 | 0.8414 |
| N-ACETYL-HEXOSAMINE | 0.8472 | 1.6384 | 0.9334 |
| N-ACETYL-L-ALANINE | 0.7958 | 0.8195 | 1.1178 |
| N-ACETYL-L-ASPARTIC ACID | 1.7178 | 1.0803 | 0.6968 |
| N-ACETYLNEURAMINATE | 0.9734 | 1.3524 | 0.9402 |
| N-BOC-L-Aspartic Acid_R1 | 0.8388 | 1.0458 | 1.0553 |
| N-BOC-L-Aspartic Acid_R2 | 0.8438 | 1.0251 | 1.0575 |
| N-BOC-L-tert-Leucine_R1 | 0.8891 | 1.0647 | 1.0314 |
| N-BOC-L-tert-Leucine_R2 | 0.8801 | 1.0865 | 1.0307 |
| N-BOC-L-Tryptophan_R1 | 0.8578 | 1.1714 | 1.0226 |
| N-BOC-L-Tryptophan_R2 | 0.8746 | 1.1607 | 1.0180 |
| NICOTINAMIDE | 0.9455 | 2.0076 | 0.8203 |
| N-METHYL-L-GLUTAMATE_R1 | 0.5623 | 1.7772 | 1.0197 |
| N-METHYL-L-GLUTAMATE_R2 | 0.7999 | 1.0075 | 1.0785 |
| OROTIC ACID | 0.5772 | 1.4740 | 1.0743 |
| Pantetheine | 0.4525 | 4.9927 | 0.4204 |
| Plasmenyl-LysoPE (P-18:1) | 0.3892 | 0.2928 | 1.3858 |
| Proline | 0.8072 | 0.6878 | 1.1395 |
| PYRIDOXAL | 0.8248 | 2.3289 | 0.8043 |
| PYRIDOXINE | 0.7191 | 1.6766 | 0.9770 |
| S-(5^-ADENOSYL)-L-HOMOCYSTEINE | 0.8935 | 1.5868 | 0.9252 |
| Salicylic Acid-D4 | 0.8915 | 1.0969 | 1.0240 |
| SARCOSINE/BETA-ALANINE | 0.8638 | 1.8202 | 0.8905 |
| (S)-DIHYDROOROTATE | 0.6526 | 1.5318 | 1.0326 |
| S-HEXYL-GLUTATHIONE | 1.0665 | 2.9384 | 0.5857 |
| SUCCINATE | 0.9447 | 1.9527 | 0.8316 |
| SUCCINIC ACID-13C4 | 0.8642 | 0.9163 | 1.0711 |
| TAURINE | 1.0992 | 1.8081 | 0.7987 |
| THREONINE/HOMOSERINE | 0.7968 | 1.0299 | 1.0753 |
| THYMIDINE 5^-MONOPHOSPHATE | 1.2208 | 1.4303 | 0.8256 |
| Tryptophan | 0.7385 | 0.9110 | 1.1224 |
| UDP | 2.3361 | 1.6280 | 0.3399 |
| URACIL | 0.7767 | 1.6042 | 0.9685 |
| URATE | 0.7927 | 1.6447 | 0.9540 |
| URIDINE | 1.1703 | 1.2788 | 0.8761 |
| URIDINE-5-MONOPHOSPHATE | 0.8324 | 1.7801 | 0.9110 |
| XANTHINE | 0.6413 | 1.2579 | 1.0919 |
Factors:
| F1 | Treatment:5mM Disodium acetate |
| F2 | Treatment:6mM Sodium Citrate |
| F3 | Treatment:Untreated |
