Data for (Study ST000759)
(Analysis AN001194)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 |
|---|---|---|---|---|---|---|---|---|---|---|
| 16:0 LYSO PC (M+CL)- | 0.7932 | 0.9561 | 0.6999 | 0.6767 | 0.8799 | 1.0479 | 1.2214 | 1.1805 | 1.1137 | 1.1821 |
| 16:0 LYSO PC (M+HCOO)- | 0.7345 | 0.9171 | 0.7736 | 0.6853 | 0.8667 | 0.9671 | 1.3920 | 1.1689 | 1.0511 | 1.1852 |
| 18:0 LYSO-PE (M-H)- | 0.6332 | 0.6583 | 0.5259 | 0.4146 | 0.7282 | 0.9428 | 1.3221 | 1.1209 | 1.0433 | 1.9856 |
| 2-DEOXY-D-GLUCOSE (M+CL)- | 1.0115 | 1.1708 | 1.3216 | 1.0357 | 0.3833 | 0.1571 | 2.4125 | 1.5478 | 0.2049 | 0.5781 |
| 2-HYDROXY-3-METHYLBUTYRIC ACID (M-H)- | 0.9179 | 0.5640 | 0.8423 | 0.6598 | 1.3034 | 2.4686 | 0.4957 | 0.6736 | 1.0084 | 1.1798 |
| 2-HYDROXYBUTYRIC ACID (M-H)- | 0.8493 | 1.1185 | 1.0604 | 0.8269 | 0.7551 | 1.2507 | 0.8207 | 0.8685 | 0.7780 | 1.5737 |
| 3-(2-HYDROXYPHENYL)PROPANOIC ACID (M-H)- | 0.9985 | 0.5194 | 0.9533 | 0.5587 | 2.0054 | 1.1710 | 0.8591 | 0.9085 | 0.7890 | 0.8943 |
| 3-HYDROXY-3-METHYLGLUTARIC ACID (M-H)- | 0.2861 | 0.4100 | 0.5117 | 0.3822 | 1.2763 | 0.8060 | 1.0263 | 0.9767 | 1.9146 | 1.6347 |
| 4-COUMARIC ACID (M-H)- | 2.2185 | 1.5973 | 1.4108 | 1.0545 | 1.7732 | 1.4660 | 0.4647 | 0.3092 | 0.3158 | 0.3590 |
| 4-HYDROXYBENZOIC ACID (M-H)- | 0.7166 | 0.9028 | 0.9088 | 0.7777 | 1.1804 | 1.1979 | NA | 0.5175 | 1.1229 | 1.2169 |
| 4-NITROPHENOL (M-H)- | 1.0542 | 0.9639 | 1.0474 | 1.1030 | 0.9853 | 1.0534 | 0.8086 | 0.9104 | 1.0509 | 1.0452 |
| 4-PYRIDOXIC ACID (M-H)- | 0.3938 | 0.2598 | 0.2478 | 0.1564 | 1.0483 | 0.6519 | 0.9589 | 1.1189 | 2.5451 | 1.5594 |
| 5^-METHYLTHIOADENOSINE (M+CL)- | 0.4969 | 0.4576 | 0.4847 | 0.4608 | 0.8293 | 0.9014 | 0.6993 | 0.6299 | 2.3552 | 1.7669 |
| 5-VALEROLACTONE (M+HCOO)- | 1.0800 | 0.2118 | NA | NA | 0.9125 | 0.8374 | 0.4174 | 0.4803 | 1.3227 | 1.8808 |
| ADENOSINE 5^-MONOPHOSPHATE (M-H)- | NA | NA | NA | NA | 0.5578 | 0.5375 | NA | NA | 1.2579 | 1.4801 |
| ADENOSINE (M+CL)- | 0.0194 | 0.0521 | 0.0285 | 0.0401 | 0.7172 | 0.4373 | 2.7412 | 2.3157 | 2.3824 | 1.9879 |
| ADIPIC ACID (M-H)- | 1.0470 | 1.0559 | 1.0585 | 1.2394 | 0.2561 | 0.3656 | 0.3363 | 0.4349 | 2.3928 | 1.2827 |
| ALLANTOIN (M-H)- | 1.5593 | 1.3721 | 1.8967 | 1.8489 | 0.4708 | 0.5651 | 0.5798 | 0.2218 | 0.6799 | 0.7868 |
| ARACHIDIC ACID (M-H)- | 0.4303 | 0.6768 | 0.6643 | 0.6789 | 0.7158 | 0.5815 | 1.8796 | 1.3843 | 0.7371 | 1.0488 |
| ARACHIDONIC ACID (M-H)- | 0.4803 | 0.8943 | 0.6533 | 0.6222 | 0.6694 | 0.7659 | 1.6085 | 0.9440 | 1.3803 | 1.4357 |
| AZELAIC ACID (M-H)- | 1.2014 | 0.9422 | 0.9253 | 0.8916 | 1.1104 | 1.0972 | 0.5252 | 0.4628 | 1.3392 | 1.3922 |
| BEHENIC ACID (M-H)- | 0.5433 | 0.8184 | 0.8520 | 0.5219 | 0.5055 | 0.5454 | 1.9770 | 1.2475 | 0.6819 | 0.9778 |
| BENZOIC ACID (M-H)- | 0.9913 | 1.2890 | 1.0399 | 1.0266 | 1.1820 | 1.0531 | 0.6481 | 0.7441 | 1.0522 | 1.0662 |
| CHOLIC ACID (2M-H)- | 0.4902 | 0.4944 | 0.3829 | 0.2175 | 0.3448 | 0.5318 | 0.6797 | 1.5673 | 1.3819 | 2.7712 |
| CHOLIC ACID (M-H)- | 1.0837 | 1.4238 | 0.6526 | 0.5477 | 0.4612 | 0.6062 | 0.5138 | 0.8151 | 2.2078 | 1.1680 |
| CIS-11-EICOSENOIC ACID (M-H)- | 0.4598 | 0.8459 | 0.7273 | 0.7647 | 0.4485 | 0.8492 | 1.7454 | 1.2734 | 1.0444 | 1.3762 |
| CIS-ACONITIC ACID (M-H)- | 0.2959 | 0.0446 | NA | NA | 2.5529 | 2.7581 | 0.2081 | 0.3189 | 0.8350 | 0.6965 |
| CITRAMALIC ACID (M-H)- | 0.8196 | 0.2427 | 0.3338 | 0.1821 | 1.2774 | 1.3415 | 0.6001 | 1.0667 | 1.5524 | 1.2563 |
| CITRIC ACID (M-H)- | 0.1227 | 0.0247 | 0.0287 | 0.0146 | 2.1629 | 2.0884 | 0.1233 | 0.1844 | 2.1131 | 2.3358 |
| CORTICOSTERONE (M+CL)- | 0.2599 | 0.6702 | 0.9229 | 0.5093 | 1.7275 | 1.4217 | 1.4659 | 0.9420 | 1.2135 | 0.7722 |
| CORTICOSTERONE (M+HCOO)- | 0.2110 | 0.5199 | 0.7072 | 0.4226 | 2.0026 | 1.8346 | 1.0372 | 0.6963 | 1.4971 | 0.9265 |
| DEHYDROASCORBIC ACID (M-H)- | 0.1431 | 0.0019 | NA | NA | 1.3316 | 1.3103 | 0.0849 | 0.1042 | 1.7129 | 1.6773 |
| DEOXYCHOLIC ACID (2M-H)- | 0.8888 | 0.5245 | 0.2640 | 0.1537 | 0.2459 | 1.0947 | 0.4108 | 1.5465 | 1.2782 | 1.7582 |
| DEOXYCHOLIC ACID (M-H)- | 0.3830 | 0.3387 | 0.4555 | 0.3685 | 0.6716 | 0.6496 | 0.7910 | 1.5646 | 1.5815 | 1.8297 |
| DEOXYURIDINE (M+CL)- | 0.8378 | 0.9333 | 0.7268 | 0.6591 | 0.7725 | 1.5585 | 0.8510 | 1.2157 | 1.1078 | 1.1779 |
| DOCOSAHEXAENOIC ACID (M-H)- | 0.6753 | 1.2303 | 0.9725 | 0.8676 | 0.7062 | 0.8494 | 0.7032 | 0.6417 | 1.3337 | 1.6780 |
| EDTA (M-H)- | NA | NA | NA | NA | 1.6662 | 0.8433 | NA | NA | 0.6389 | 0.9352 |
| ERUCIC ACID (M-H)- | 0.3896 | 0.6004 | 0.4038 | 0.5104 | 0.4655 | 0.6710 | 2.0563 | 1.5053 | 0.7744 | 1.1062 |
| ETHYLMALONIC ACID (M-H)- | 0.8411 | 0.3153 | 0.4455 | 0.3853 | 0.7450 | 0.8602 | 0.6886 | 1.2663 | 1.7283 | 1.2217 |
| GLUCOSE (M+CL)- | 0.8239 | 1.1578 | 1.2278 | 1.7030 | 0.2214 | 0.1449 | 2.4751 | 1.8530 | 0.1485 | 0.2706 |
| GLUTARIC ACID (M-H)- | 1.2152 | 1.3066 | 0.9073 | 0.8423 | 0.7547 | 0.8743 | 0.7567 | 0.5457 | 2.1485 | 0.4975 |
| GLYCERIC ACID (M-H)- | 0.7379 | 1.6201 | 0.8760 | 1.6948 | 0.6588 | 0.5433 | 1.4075 | 1.2378 | 0.5994 | 0.6395 |
| GLYCOCHOLIC ACID (M-H)- | 0.8837 | 0.3568 | 0.6472 | 0.5696 | 0.4747 | 0.4336 | 0.5262 | 0.2408 | 1.8818 | 2.9018 |
| HEPTADECANOIC ACID (M-H)- | 0.6188 | 0.9622 | 0.9311 | 0.9630 | 0.5316 | 0.8069 | 1.4644 | 0.9067 | 1.0008 | 1.4809 |
| HIPPURIC ACID (M-H)- | 1.1836 | 1.1040 | 0.8529 | 0.5614 | 0.9917 | 0.6389 | 1.5198 | 1.8285 | 0.5334 | 0.7879 |
| HYODEOXYCHOLIC ACID (M-H)- | 0.9040 | 1.1927 | 1.0461 | 1.0879 | 0.6515 | 1.1405 | 0.9314 | 0.8448 | 1.1836 | 0.9877 |
| INDOLE-3-ACETIC ACID (M-H)- | 0.8338 | 0.4761 | 0.7576 | 0.4640 | 1.0965 | 1.1770 | 1.0146 | 1.3455 | 1.2114 | 1.0574 |
| INOSINE (M-H)- | 0.0664 | NA | NA | NA | 0.4072 | 0.6754 | 1.1943 | 1.8332 | 0.5436 | 0.5548 |
| KYNURENIC ACID (M-H)- | 1.7815 | 0.7638 | 0.4871 | NA | 1.9107 | 1.0611 | 0.6522 | 0.8161 | 0.9066 | 0.9447 |
| L-[15N]ANTHRANILIC ACID [ISTD] (M-H)- | 1.0025 | 1.0773 | 1.1083 | 1.1610 | 1.0763 | 0.8958 | 0.9102 | 0.8571 | 1.0262 | 0.9685 |
| LEUCINE (M-H)- | 0.9475 | 0.6412 | 1.0519 | 0.7343 | 1.1119 | 1.2618 | 1.4277 | 2.1760 | 0.5240 | 0.5033 |
| LEUKOTRIENE B4 (M-H)- | NA | NA | NA | NA | NA | NA | 0.3076 | NA | 1.0136 | 1.3259 |
| LIGNOCERIC ACID (M-H)- | 0.6124 | 0.8145 | 0.6277 | 0.7363 | 0.4651 | 0.6314 | 2.5755 | 1.6072 | 0.7033 | 0.8861 |
| LINOLEIC ACID (M-H)- | 0.7396 | 1.5186 | 1.2351 | 1.1234 | 0.5989 | 0.8717 | 1.0501 | 0.5871 | 0.9656 | 1.2784 |
| L-TRYPTOPHAN-15N2 [ISTD] (M-H)- | 1.0604 | 1.1180 | 1.1988 | 1.2098 | 0.9740 | 0.9734 | 0.9157 | 0.9484 | 0.8807 | 0.8762 |
| MALEIC ACID (M-H)- | 1.2430 | 1.1156 | 1.1017 | 0.9776 | 1.3456 | 0.9690 | 0.9588 | 0.8374 | 0.8778 | 0.7485 |
| MALIC ACID (M-H)- | 0.3208 | 0.0756 | 0.2266 | 0.2181 | 2.0352 | 2.0473 | 0.5822 | 0.5119 | 1.6049 | 1.3174 |
| MALIC ACID (M-H)+[-H2O] | 1.0925 | 0.5711 | 0.9214 | 0.3802 | 1.4448 | 1.4005 | 0.8151 | 0.7958 | 1.3600 | 0.8303 |
| MANDELIC ACID #2 (M-H)- | 1.1941 | 0.1860 | NA | NA | 0.6509 | 0.8223 | 1.1549 | 0.6153 | 1.2472 | 1.2918 |
| MANDELIC ACID (M-H)- | 1.0436 | NA | 0.4447 | NA | 0.9049 | 0.9337 | 0.4021 | 0.6144 | 1.4757 | 1.4379 |
| METHYLMALONIC ACID (M-H)- | 0.4564 | 0.3762 | 0.2763 | 0.1971 | 0.4526 | 0.6285 | 1.1064 | 1.6195 | 1.8430 | 1.8269 |
| MEVALONIC ACID (M-H)- | 1.1212 | 1.4517 | 1.5219 | 1.3272 | NA | 0.8208 | 0.7956 | 0.6783 | 0.8836 | 0.6665 |
| MYRISTIC ACID (M-H)- | 0.4385 | 0.5914 | 0.6641 | 0.6045 | 0.4416 | 0.5473 | 0.8663 | 0.5383 | 1.6360 | 2.6685 |
| MYRISTOLEIC ACID (M-H)- | 0.4171 | 1.0599 | 0.6215 | 0.8046 | 0.6490 | 0.8815 | 0.8966 | 0.5647 | 1.5724 | 1.7897 |
| N-ACETYL-D-GLUCOSAMINE (M+CL)- | 0.5728 | 2.0623 | 1.9873 | NA | 0.2143 | 0.2308 | 1.6290 | 1.4226 | 0.2802 | 0.4888 |
| N-ACETYL-L-LEUCINE (M-H)- | 1.4738 | 0.6114 | 0.6824 | 0.3658 | 1.2918 | 1.4574 | 0.7766 | 1.1588 | 1.4238 | 0.7603 |
| NERVONIC ACID (M-H)- | 0.3888 | 0.5702 | 0.3587 | 0.4801 | 0.3424 | 0.7302 | 2.8937 | 1.8843 | 0.7793 | 0.9919 |
| OLEOYL-GLYCEROL (M+HCOO)- | 0.9229 | 2.5534 | 2.5420 | 1.1670 | 0.6735 | 0.7591 | 0.4136 | 0.3155 | 0.3848 | 0.5929 |
| OMEGA-HYDROXYDODECANOIC ACID (M-H)- | NA | NA | NA | NA | NA | NA | NA | NA | 0.8325 | 1.1675 |
| PALMITIC ACID (M-H)- | 0.5320 | 0.9658 | 1.0459 | 1.0235 | 0.5315 | 0.6772 | 1.2675 | 0.6000 | 1.2456 | 1.6809 |
| PALMITOLEIC ACID (M-H)- | 0.7551 | 2.0886 | 1.2474 | 1.5069 | 0.3603 | 0.5207 | 0.9249 | 0.3669 | 0.7680 | 1.5028 |
| PANTOTHENIC ACID (M+CL)- | 0.6643 | 0.2533 | NA | NA | 0.9467 | 0.9779 | 0.5200 | 1.0063 | 1.0017 | 1.6248 |
| PANTOTHENIC ACID (M-H)- | 0.5626 | 0.5196 | 0.3772 | 0.2998 | 0.8785 | 1.2199 | 0.7029 | 0.9576 | 1.4325 | 2.2787 |
| PHENYLALANINE (M-H)- | 0.9767 | 0.6163 | 0.8279 | 0.6506 | 0.8822 | 1.3945 | 1.2666 | 1.3820 | 0.9702 | 0.9238 |
| PIMELIC ACID (M-H)- | NA | 0.5929 | 0.5266 | NA | 0.6960 | NA | 0.3386 | NA | 1.6203 | 0.9851 |
| PYRUVIC ACID (M-H)- | 0.6605 | 1.3131 | 1.4195 | 1.6104 | 0.3505 | 0.8038 | NA | NA | 1.5646 | 0.7512 |
| SALICYLATE #2 (M-H)- | 1.2823 | 1.0804 | 1.3844 | 0.8330 | 1.6844 | 1.2296 | 1.1961 | 1.3573 | 0.2004 | 0.3423 |
| SEBACIC ACID (M-H)- | 0.1762 | 0.1197 | 0.1505 | 0.1454 | 0.2220 | 0.2258 | 0.1330 | 0.1189 | 2.4166 | 2.7699 |
| STEARIC ACID (M-H)- | 0.5368 | 0.6097 | 0.3079 | 0.4540 | 0.5107 | 0.7424 | 2.7966 | 1.9949 | 0.5173 | 1.0489 |
| SUBERIC ACID (M-H)- | 0.7555 | 0.5339 | 0.6479 | 0.5498 | 0.6996 | 0.6984 | 0.5625 | 0.9231 | 1.7707 | 1.6747 |
| SUCCINIC ACID (M-H)- | 0.8272 | 1.1836 | 0.9366 | 1.2421 | 0.3733 | 0.3703 | 1.3395 | 1.1401 | 1.9125 | 0.3991 |
| THYMIDINE (M+CL)- | 0.5350 | 0.4606 | 0.3998 | 0.3158 | 1.1880 | 1.0841 | 0.7224 | 0.7075 | 2.3231 | 1.4964 |
| THYMIDINE (M+HCOO)- | 0.7962 | 0.9476 | 0.8518 | 0.7809 | 0.8204 | 1.0383 | 1.0161 | 1.0218 | 1.3080 | 1.1703 |
| TRANS-ACONITIC ACID (M-H)- | 0.1268 | 0.0747 | 0.0614 | 0.0473 | 1.6850 | 1.6017 | 0.2351 | 0.2603 | 2.3166 | 2.1886 |
| TRANS-VACCENIC ACID (M-H)- | 0.6052 | 1.5931 | 1.1720 | 1.1661 | 0.4632 | 0.6990 | 1.1558 | 0.4677 | 0.9753 | 1.5395 |
| TRICARBALLYLIC ACID (M-H)- | 0.1807 | 0.0366 | 0.0175 | 0.0258 | 1.0380 | 0.9806 | 0.2189 | 0.2300 | 2.5765 | 1.7877 |
| TRICARBALLYLIC ACID (M-H)-[-H2O] | 0.1678 | 0.2067 | 0.1269 | 0.1297 | 0.6737 | 0.6421 | 0.1278 | 0.1626 | 2.5569 | 1.3146 |
| TRICOSANOIC ACID (M-H)- | 0.6229 | 0.7878 | 0.7774 | 0.7503 | 0.5133 | 0.6402 | 1.8146 | 1.4498 | 0.7591 | 0.8059 |
| TRYPTOPHAN (M-H)- | 1.0368 | 0.9472 | 0.9829 | 0.7994 | 1.1272 | 1.1540 | 1.2508 | 1.2754 | 0.7133 | 0.8166 |
| TYROSINE (M-H)- | 1.2142 | 0.7408 | 0.7443 | 0.7637 | 1.0077 | 1.4025 | 1.0570 | 1.4309 | 0.6613 | 1.0167 |
| URIC ACID (M-H)- | 0.7053 | 0.8292 | 0.9424 | 0.8852 | 0.7247 | 0.5166 | 2.1255 | 2.0712 | 0.5732 | 0.5272 |
| URIDINE (M+CL)- | 0.6510 | 0.8023 | 0.7959 | 0.6930 | 0.4712 | 0.5486 | 1.7482 | 2.0188 | 1.0361 | 0.8500 |
| URIDINE (M-H)- | 0.6242 | 0.7669 | 0.8310 | 0.7588 | 0.6041 | 1.5129 | 1.2556 | 1.8249 | 0.8140 | 0.7821 |
| URSODIOL (M+HCOO)- | 0.3585 | 0.3546 | 0.2324 | 0.4110 | 0.3347 | 1.1301 | 0.6124 | 1.0274 | 3.1459 | 1.2734 |
| XANTHOSINE (M-H)- | NA | NA | NA | NA | 0.1175 | NA | 0.1560 | NA | 1.7083 | 0.3692 |
| ZEATIN [ISTD] (M+CL)- | 0.7403 | 0.7649 | 0.8194 | 0.7446 | 1.1711 | 1.2684 | 0.9266 | 0.8776 | 1.2388 | 1.2519 |
| ZEATIN [ISTD] (M-H)- | 0.8121 | 0.8585 | 0.9126 | 0.8479 | 1.1045 | 1.2258 | 0.9898 | 0.9219 | 1.0955 | 1.1371 |
Factors:
| F1 | Age:106 week | Line:HRT | Sex:Female | Training:no |
| F2 | Age:106 week | Line:HRT | Sex:Female | Training:yes |
| F3 | Age:106 week | Line:LRT | Sex:Female | Training:no |
| F4 | Age:106 week | Line:LRT | Sex:Female | Training:yes |
| F5 | Age:126 week | Line:HCR | Sex:Male | Training:no |
| F6 | Age:126 week | Line:LCR | Sex:Male | Training:no |
| F7 | Age:14 week | Line:HCR | Sex:Male | Training:no |
| F8 | Age:14 week | Line:LCR | Sex:Male | Training:no |
| F9 | Age:4 week | Line:HCR | Sex:Male | Training:no |
| F10 | Age:4 week | Line:LCR | Sex:Male | Training:no |
