Data for Biomarkers of NAFLD progression: a lipidomics approach to an epidemic. Part 2:Liver (Study ST000915)
(Analysis AN001486)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 14-demethyl-14-dehydrolanosterol | 0.3160 | 1.7856 | 0.7184 | 1.3940 |
| 14-Demethyllanosterol | 1.0851 | 1.0567 | 0.9434 | 0.9365 |
| 19-hydroxycholesterol | NA | NA | NA | NA |
| 20-hydroxycholesterol | NA | NA | NA | NA |
| 22R-hydroxy-cholesterol | 0.6435 | 0.7959 | 1.3644 | 0.9951 |
| 24,25-epoxy-cholesterol | 0.9664 | 1.3757 | 0.9730 | 0.6854 |
| 24-dihydro Lanosterol | 0.8991 | 1.0803 | 0.8770 | 1.2422 |
| 24-oxocholesterol | 1.1748 | 0.6518 | 0.9400 | 1.3133 |
| 24S-hydroxy-cholesterol | 1.2109 | 1.1100 | 0.7875 | 1.0099 |
| 25-hydroxy-cholesterol | 0.3860 | 3.1259 | 0.2727 | 0.3830 |
| 25-hydroxy Vitamin D2 | NA | NA | NA | NA |
| 25-hydroxy Vitamin D3 | NA | NA | NA | NA |
| 27-hydroxy-cholesterol | 0.8286 | 1.1882 | 0.8046 | 1.3364 |
| 3beta,5alpha,6beta-trihydroxycholestanol | NA | NA | NA | NA |
| 3-oxo,7alpha-hydroxycholesterol | 0.4728 | 1.7743 | 0.7202 | 1.2666 |
| 4beta-hydroxy-cholesterol | 0.8567 | 0.7363 | 1.2362 | 1.0481 |
| 5,6alpha-epoxy-cholesterol | 1.0506 | 0.9728 | 0.9030 | 1.1494 |
| 5,6beta-epoxy-cholesterol | 1.2146 | 0.8892 | 0.8836 | 1.0901 |
| 5alpha,6alpha-24S,25-diepoxy-cholesterol | 1.2100 | 0.8984 | 0.6802 | 1.6377 |
| 5alpha-hydroxycholesterol | 1.1119 | 0.8799 | 0.8421 | 1.3041 |
| 6alpha-hydroxy-cholestanol | 1.3180 | 0.6908 | 0.9768 | 1.1278 |
| 7alpha,24S-dihydroxycholesterol | NA | NA | NA | NA |
| 7alpha,25-dihydroxycholesterol | NA | NA | NA | NA |
| 7alpha,27-dihydroxy cholesterol | NA | 1.0348 | 0.8608 | NA |
| 7alpha-hydroxy-cholesterol | 0.7563 | 1.1687 | 0.9012 | 1.2684 |
| 7-Dehydrochol | 0.5795 | 1.2518 | 0.8082 | 1.5482 |
| 7-oxo-cholesterol | 0.8757 | 0.8907 | 1.1670 | 0.9703 |
| 8-Dehydrochol | 0.5699 | 1.5623 | 0.7228 | 1.3500 |
| Campesterol | 1.1325 | 1.0279 | 0.8684 | 1.0513 |
| Cholestanol | 1.5405 | 0.8274 | 0.7975 | 0.9365 |
| Cholestenone | 0.7978 | 0.9539 | 0.9375 | 1.4062 |
| Cholesterol-free | 0.8353 | 1.0741 | 0.9445 | 1.2356 |
| Cholesterol-total | 1.0483 | 0.9914 | 0.8975 | 1.1589 |
| Desmosterol | 1.1842 | 1.0476 | 0.6317 | 1.3988 |
| Lanosterol | 0.3906 | 1.6409 | 0.8240 | 1.2839 |
| Sitosterol | 1.1343 | 0.9271 | 0.9257 | 1.0633 |
| Stigmastanol | 0.7809 | 1.1845 | 0.9504 | 1.1311 |
| Stigmasterol | 0.9143 | 1.0079 | 1.0034 | 1.0658 |
| Zymosterol | 0.9442 | 1.2584 | 0.5497 | 1.4710 |
Factors:
| F1 | Diagnosis:Cirrhosis |
| F2 | Diagnosis:NASH |
| F3 | Diagnosis:Normal |
| F4 | Diagnosis:Steatosis |
