Data for Biomarkers of NAFLD progression: a lipidomics approach to an epidemic. Part 2:Liver (Study ST000915)
(Analysis AN001489)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| C14 Cer | 0.7388 | 0.9252 | 1.2342 | 0.9682 |
| C14DH Cer | 0.8770 | 0.7623 | 1.2901 | 0.8954 |
| C14DH HexCer | 0.3100 | 0.6139 | 2.0837 | 0.2897 |
| C14DH Sphingomyelin | 1.3024 | 1.0057 | 0.9661 | 0.6994 |
| C14 GalCer | 1.1818 | 0.9933 | 0.9286 | 0.9241 |
| C14 GlcCer | 0.7928 | 1.0239 | 1.2959 | 0.6762 |
| C14 HexCer | 0.8961 | 1.0158 | 1.1983 | 0.7420 |
| C14 Sphingomyelin | 0.9626 | 1.0625 | 1.1299 | 0.7337 |
| C16 1-deoxyCer | 1.0547 | 0.8997 | 0.9318 | 1.1780 |
| C16 Cer | 0.8147 | 0.9208 | 1.0300 | 1.2565 |
| C16DH 1-deoxyCer | 0.4575 | 1.6541 | 0.9908 | 0.8854 |
| C16DH Cer | 1.1110 | 1.1227 | 0.9070 | 0.8946 |
| C16DH HexCer | 1.4443 | 0.9009 | 0.9415 | 0.6721 |
| C16DH Sphingomyelin | 1.4683 | 0.9079 | 0.8964 | 0.7463 |
| C16 GalCer | 0.9591 | 1.0010 | 1.0458 | 0.9635 |
| C16 GlcCer | 0.9559 | 1.1420 | 1.0064 | 0.8732 |
| C16 HexCer | 0.9560 | 1.1390 | 1.0072 | 0.8751 |
| C16 Sphingomyelin | 1.1720 | 0.9639 | 1.0191 | 0.8054 |
| C18:1 Cer | 0.6680 | 1.0082 | 1.0894 | 1.2178 |
| C18 1-deoxyCer | 0.6535 | 1.3024 | 0.9073 | 1.2210 |
| C18:1DH Cer | 0.7590 | 1.0020 | 1.2381 | 0.8470 |
| C18:1DH HexCer | 1.4345 | 1.6939 | 0.6488 | 0.2923 |
| C18:1 GalCer | 1.0260 | 0.9343 | 1.1748 | 0.7278 |
| C18:1 GlcCer | 0.9339 | 0.9727 | 1.2761 | 0.6066 |
| C18:1 HexCer | 0.9656 | 0.9595 | 1.2412 | 0.6484 |
| C18:1 Sphingomyelin | 0.6793 | 1.1506 | 1.2647 | 0.7173 |
| C18 Cer | 0.5220 | 1.0322 | 1.1605 | 1.2319 |
| C18DH 1-deoxyCer | 0.3672 | 1.4531 | 1.0394 | 1.1396 |
| C18DH Cer | 0.6833 | 0.9803 | 1.2765 | 0.8916 |
| C18DH HexCer | 0.9443 | 1.2624 | 1.0620 | 0.6438 |
| C18DH Sphingomyelin | 1.1390 | 1.0404 | 0.9628 | 0.8568 |
| C18 GalCer | 1.0646 | 0.8709 | 1.0548 | 0.9760 |
| C18 GlcCer | 0.8094 | 1.3907 | 0.9632 | 0.8318 |
| C18 HexCer | 0.8261 | 1.3567 | 0.9692 | 0.8412 |
| C18 Sphingomyelin | 0.8503 | 1.0357 | 1.1327 | 0.8922 |
| C20 1-deoxyCer | 0.7836 | 1.3412 | 0.7694 | 1.2737 |
| C20 Cer | 0.6151 | 1.0055 | 1.1587 | 1.1570 |
| C20DH 1-deoxyCer | 0.4122 | 1.5313 | 1.0006 | 1.0654 |
| C20DH Cer | 0.8734 | 1.1232 | 1.0466 | 0.9191 |
| C20DH HexCer | 0.9702 | 1.0474 | 1.2763 | 0.4755 |
| C20DH Sphingomyelin | 1.0173 | 1.0206 | 1.0520 | 0.8606 |
| C20 GalCer | 1.1977 | 1.0747 | 0.9338 | 0.8003 |
| C20 GlcCer | 0.9683 | 1.1432 | 0.9948 | 0.8783 |
| C20 HexCer | 0.9837 | 1.1386 | 0.9907 | 0.8731 |
| C20 Sphingomyelin | 0.7465 | 1.0354 | 1.1329 | 1.0143 |
| C22 1-deoxyCer | 0.6189 | 1.4267 | 0.8272 | 1.2615 |
| C22 Cer | 0.5088 | 1.0836 | 1.1520 | 1.2023 |
| C22DH 1-deoxyCer | 0.3508 | 1.6358 | 0.9797 | 1.0527 |
| C22DH Cer | 0.8083 | 1.2837 | 0.9603 | 0.9641 |
| C22DH HexCer | 0.9478 | 1.0696 | 1.0516 | 0.8827 |
| C22DH Sphingomyelin | 0.8340 | 1.0965 | 1.0684 | 0.9570 |
| C22 GalCer | 0.8881 | 0.7180 | 1.1729 | 1.1398 |
| C22 GlcCer | 0.6904 | 1.1311 | 1.0805 | 1.0754 |
| C22 HexCer | 0.6943 | 1.1231 | 1.0823 | 1.0767 |
| C22 Sphingomyelin | 0.7532 | 1.0254 | 1.1559 | 0.9762 |
| C24:1 1-deoxyCer | 1.0538 | 1.3202 | 0.7637 | 0.9910 |
| C24:1 Cer | 0.9856 | 1.0175 | 1.0291 | 0.9434 |
| C24 1-deoxyCer | 0.6238 | 1.3829 | 0.8279 | 1.3059 |
| C24:1DH 1-deoxyCer | 0.6553 | 1.5446 | 0.9354 | 0.8827 |
| C24:1DH Cer | 1.2212 | 1.1891 | 0.8472 | 0.7959 |
| C24:1DH HexCer | 1.1599 | 1.0177 | 1.0371 | 0.6927 |
| C24:1 GalCer | 1.0511 | 0.9133 | 0.9400 | 1.1538 |
| C24:1 GlcCer | 1.2203 | 1.0545 | 0.9226 | 0.8179 |
| C24:1 HexCer | 1.2134 | 1.0513 | 0.9231 | 0.8288 |
| C24:1 Sphingomyelin | 1.1851 | 0.9672 | 1.0095 | 0.8036 |
| C24 Cer | 0.5501 | 1.1263 | 1.1491 | 1.1088 |
| C24DH 1-deoxyCer | 0.3985 | 1.5250 | 1.0346 | 1.0270 |
| C24DH Cer | 0.8313 | 1.2883 | 0.9488 | 0.9526 |
| C24DH HexCer | 1.1256 | 1.1305 | 0.9407 | 0.7987 |
| C24DH Sphingomyelin | 0.7928 | 1.0813 | 1.1065 | 0.9539 |
| C24 GalCer | 0.7536 | 0.8103 | 1.0682 | 1.3525 |
| C24 GlcCer | 0.7209 | 1.1174 | 1.0679 | 1.0664 |
| C24 HexCer | 0.7207 | 1.1109 | 1.0682 | 1.0737 |
| C24 Sphingomyelin | 0.8510 | 1.0135 | 1.1139 | 0.9518 |
| C26:1 1-deoxyCer | 1.9356 | 0.5771 | 0.6791 | 0.9819 |
| C26:1 Cer | 1.0716 | 0.9798 | 1.0874 | 0.7800 |
| C26 1-deoxyCer | 0.8696 | 1.3557 | 0.8648 | 0.9816 |
| C26:1DH 1-deoxyCer | 1.0627 | 1.0630 | 0.7784 | 1.2432 |
| C26:1DH Cer | 0.7207 | 0.9382 | 1.3332 | 0.7937 |
| C26:1DH HexCer | 1.2727 | 0.8446 | 1.2244 | 0.4430 |
| C26:1 GalCer | 1.4758 | 1.1291 | 0.7138 | 0.8103 |
| C26:1 GlcCer | 0.9642 | 1.4647 | 1.0756 | 0.3150 |
| C26:1 HexCer | 1.0306 | 1.4243 | 1.0283 | 0.3784 |
| C26:1 Sphingomyelin | 1.2923 | 0.9557 | 0.9514 | 0.7969 |
| C26 Cer | 0.6553 | 1.1214 | 1.2052 | 0.8885 |
| C26DH 1-deoxyCer | 0.7267 | 0.9263 | 0.8581 | 1.7087 |
| C26DH Cer | 0.7868 | 0.8755 | 1.1303 | 1.1597 |
| C26DH HexCer | 0.7326 | 0.9742 | 1.3092 | 0.7654 |
| C26DH Sphingomyelin | 0.8200 | 1.2158 | 1.1790 | 0.6314 |
| C26 GalCer | 1.0613 | 1.2420 | 0.8891 | 0.8189 |
| C26 GlcCer | 1.2536 | 1.0906 | 1.1707 | 0.2869 |
| C26 HexCer | 1.2046 | 1.1292 | 1.0989 | 0.4225 |
| C26 Sphingomyelin | 1.0308 | 1.0533 | 1.0458 | 0.8175 |
| Sphinganine | 0.7300 | 1.3705 | 0.8556 | 1.1452 |
| Sphinganine-P | 0.7990 | 1.1820 | 1.0091 | 1.0058 |
| Sphingosine | 0.5805 | 1.2063 | 0.9685 | 1.3082 |
| Sphingosine-P | 0.3977 | 1.3331 | 1.2132 | 0.9279 |
Factors:
| F1 | Diagnosis:Cirrhosis |
| F2 | Diagnosis:NASH |
| F3 | Diagnosis:Normal |
| F4 | Diagnosis:Steatosis |
