Data for TCA cycle metabolomics of H3K27M Cell Nucleus Fraction and Cell Mitonchonrdial Fraction (Part-IV) (Study ST001026)
(Analysis AN001683)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2-Hydroxyglutarate | 0.6383 | 0.4255 | 0.2128 | 1.4894 | 0.4255 | NA | 0.6383 | NA | 0.5674 | 2.5532 | 0.4255 | 0.9574 |
| Aspartate | 0.3637 | 0.3414 | 1.2952 | 0.2648 | 0.7274 | 2.7978 | 0.5200 | 0.3701 | 1.4898 | 0.3605 | 0.7082 | 2.5490 |
| cis-Aconitic Acid | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Citrate | 0.3541 | 0.4772 | 0.9807 | 0.2499 | 0.5965 | 2.1309 | 1.4667 | 0.9330 | 1.7341 | 0.3943 | 0.7007 | 1.7668 |
| Fumarate | 0.3881 | 1.0597 | 0.6493 | NA | 2.5821 | 0.5970 | 0.3284 | 0.5075 | 0.8731 | 2.1343 | NA | NA |
| Glutamate | 0.7874 | 1.1048 | 1.5788 | 0.7091 | 0.8580 | 1.0617 | 0.9206 | 0.7208 | 1.2184 | 0.5406 | 0.5681 | 1.8609 |
| Isocitrate | 0.1471 | 0.2353 | 0.5686 | 0.0588 | 0.2549 | 0.7647 | 1.3529 | 0.9608 | 3.6471 | 0.1569 | 0.4706 | 2.4706 |
| Ketoglutarate | 0.8617 | 0.3977 | 0.5303 | 1.5246 | 0.5082 | 0.6850 | 2.4747 | 0.7734 | 0.7513 | 1.8119 | 0.6187 | 1.0164 |
| Lactate | 0.9431 | 0.8793 | 0.4636 | 1.2950 | 1.2141 | 0.8854 | 0.9639 | 0.5960 | 0.6120 | 1.4520 | 1.0351 | 1.6605 |
| Malate | 0.9697 | 0.6281 | 1.0689 | 0.3416 | 0.4518 | 3.3278 | 0.7603 | 0.4738 | 1.0248 | 0.8044 | 0.5840 | 1.5647 |
| Oxaloacetate | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| Succinate | 0.5021 | 0.3013 | 0.9289 | 0.3766 | 0.5272 | 1.4059 | 1.1046 | 0.6276 | 2.1841 | 0.5021 | 0.6527 | 2.8870 |
Factors:
| F1 | sample type:Mito Fraction | Grouping:IV aKG |
| F2 | sample type:Mito Fraction | Grouping:IV GF |
| F3 | sample type:Mito Fraction | Grouping:IV REG |
| F4 | sample type:Mito Fraction | Grouping:XVII aKG |
| F5 | sample type:Mito Fraction | Grouping:XVII GF |
| F6 | sample type:Mito Fraction | Grouping:XVII REG |
| F7 | sample type:Nucleus fraction | Grouping:IV aKG |
| F8 | sample type:Nucleus fraction | Grouping:IV GF |
| F9 | sample type:Nucleus fraction | Grouping:IV REG |
| F10 | sample type:Nucleus fraction | Grouping:XVII aKG |
| F11 | sample type:Nucleus fraction | Grouping:XVII GF |
| F12 | sample type:Nucleus fraction | Grouping:XVII REG |
