Data for Aspirin Metabolomics in Colorectal Cancer Chemoprevention (part 1 - Colon) (Study ST001091)
(Analysis AN001776)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 |
|---|---|---|---|---|---|
| 1-Aminocyclopropanecarboxylic acid | 1.1744 | 1.1021 | 0.8506 | 0.3107 | 1.1081 |
| 5-Aminolevulinic acid | 0.6364 | 0.5540 | 3.3516 | 1.3338 | 0.5962 |
| Aminoadipic acid | 1.3476 | 0.8461 | 0.9622 | 0.4540 | 0.8965 |
| Anserine | 1.1525 | 1.0184 | 0.4432 | 0.2947 | 1.2204 |
| Arabitol | 0.8839 | 0.7690 | 2.4862 | 0.3963 | 0.7966 |
| Benzylamine | 1.0644 | 1.0182 | 1.9255 | 0.3716 | 0.6060 |
| Cholic acid | 1.0885 | 0.9934 | 0.7157 | 0.4736 | 1.0634 |
| Creatine | 1.0707 | 0.9759 | 1.4283 | 0.2129 | 0.9882 |
| Creatinine | 0.3929 | 0.3682 | 4.2530 | 1.8349 | 0.4033 |
| Cystathionine | 1.0585 | 0.8058 | 1.5207 | 0.3175 | 0.8530 |
| Cystine | 1.2513 | 1.0722 | 0.6626 | 0.3430 | 1.0438 |
| Dethiobiotin | 1.3248 | 1.0140 | 0.2968 | 0.2579 | 1.1028 |
| Dodecanoylcarnitine | 0.5924 | 0.6196 | 1.1201 | 2.7479 | 0.6437 |
| Ergocalciferol | 1.1938 | 0.8639 | NA | NA | 0.9273 |
| Glucosamine | 1.4569 | 0.8303 | 1.2454 | 0.2499 | 0.8047 |
| Glutamic acid | 1.1332 | 1.0464 | 0.9922 | 0.2615 | 1.0628 |
| Glutamine | 1.1336 | 1.0509 | 0.8972 | 0.4941 | 1.0973 |
| Histidine | 1.2103 | 1.0243 | 0.5301 | 0.7173 | 1.1033 |
| Hypotaurine | 0.9649 | 0.9503 | 1.9891 | 0.2805 | 0.9721 |
| Imidazoleacetic acid | 1.0969 | 1.1691 | 0.2392 | 0.1504 | 1.0375 |
| Indole | 1.1160 | 1.0222 | 0.3967 | 1.1756 | 1.0379 |
| Indoleacetic acid | 0.3704 | 0.2807 | 5.1499 | 0.6178 | 0.2986 |
| Kynurenic acid | 2.3726 | 1.6477 | 0.6044 | 0.4131 | 0.8437 |
| Kynurenine | 1.3299 | 1.0462 | 0.4732 | 0.5560 | 1.0593 |
| Lysine | 1.2164 | 1.1021 | 0.5194 | 0.3849 | 1.0905 |
| Malic acid | 1.0537 | 0.8850 | 1.2712 | 0.3994 | 1.0196 |
| N-Acetyl-L-aspartic acid | 1.0354 | 1.0012 | 1.0190 | NA | 0.9526 |
| Nicotine | 1.1217 | 0.8242 | 1.5357 | 0.9877 | 0.8733 |
| Ornithine | 1.0518 | 0.6655 | 0.7124 | 2.1293 | 0.6720 |
| Phenylethylamine | 1.1339 | 1.0468 | 2.1247 | 0.2694 | 0.4850 |
| Phenylpyruvic acid | 1.1425 | 1.0319 | 0.8827 | 0.3700 | 1.0655 |
| Phosphocreatine | 0.3575 | 0.3041 | 3.0204 | 0.0545 | 0.3728 |
| Proline | 1.2115 | 1.1163 | 0.4067 | 0.6026 | 1.1183 |
| Serine | 1.2043 | 1.1625 | 0.3772 | 0.3917 | 1.1384 |
| Sphinganine | 1.0725 | 0.9382 | 0.0529 | 0.0796 | 1.1259 |
| Taurine | 1.1069 | 0.9910 | 1.2835 | 0.1905 | 1.0077 |
| Tryptophan | 0.9142 | 0.9186 | 0.3333 | 2.1222 | 0.9185 |
| Tyrosine | 1.1570 | 1.0841 | 0.3723 | 0.4310 | 1.1033 |
| Uric acid | 0.9479 | 1.0641 | 0.9390 | 1.1052 | 0.9627 |
| Uridine | 1.3066 | 1.0932 | 0.4186 | 0.0651 | 1.0675 |
| Urocanic acid | 1.4209 | 1.0417 | 0.5971 | 0.1385 | 0.9062 |
| Xanthine | 1.2008 | 1.0835 | 0.1962 | 0.1430 | 1.0948 |
Factors:
| F1 | Aspirin Dosage:ASA 325 | Sample.Matrix:Colon Mucosal Tissue |
| F2 | Aspirin Dosage:ASA 81 | Sample.Matrix:Colon Mucosal Tissue |
| F3 | Aspirin Dosage:NA | Sample.Matrix:Colon Mucosal Tissue |
| F4 | Aspirin Dosage:NA | Sample.Matrix:Plasma |
| F5 | Aspirin Dosage:PLACEBO | Sample.Matrix:Colon Mucosal Tissue |
