Data for Microbial depletion and ozone exposure - Lung tissue (part I) (Study ST001143)
(Analysis AN001884)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 1-(1-enyl-palmitoyl)-GPC (P-16:0)* | 1.1938 | 0.8654 | 1.1267 | 0.8542 |
| 1-palmitoyl-GPA (16:0) | 0.8178 | 0.9854 | 0.8252 | 1.2359 |
| 1-stearoyl-2-arachidonoyl-GPS (18:0/20:4) | 1.0789 | 1.0588 | 0.9051 | 0.9598 |
| 1-stearoyl-2-oleoyl-GPS (18:0/18:1)* | 1.0393 | 0.9877 | 0.9971 | 0.9823 |
| 2,3-dihydroxyisovalerate | 0.8841 | 0.8454 | 1.4231 | 0.7514 |
| 2^-deoxycytidine 5^-monophosphate | 1.7427 | 0.7209 | 0.9636 | 0.7005 |
| 2-hydroxyadipate | 0.9588 | 0.9916 | 1.0909 | 0.9545 |
| 2-hydroxyglutarate | 1.0244 | 0.8791 | 1.2809 | 0.8338 |
| 3-hydroxy-2-ethylpropionate | 1.1024 | 0.9434 | 1.0201 | 0.9526 |
| 3-hydroxy-3-methylglutarate | 0.8205 | 0.9640 | 1.1404 | 1.0572 |
| 3-hydroxybutyrate (BHBA) | 0.6921 | 0.9221 | 1.0717 | 1.2854 |
| 3-hydroxyisobutyrate | 0.9979 | 0.9964 | 1.0320 | 0.9739 |
| 4-hydroxybutyrate (GHB) | 1.1085 | 0.8936 | 1.1865 | 0.8382 |
| acetylphosphate | 0.9832 | 1.0243 | 0.9903 | 0.9970 |
| alanine | 0.9820 | 1.0492 | 0.9368 | 1.0236 |
| allantoin | 0.8937 | 0.9403 | 1.2459 | 0.9143 |
| alpha-hydroxyisovalerate | 1.6554 | 0.8717 | 0.7501 | 0.8208 |
| alpha-ketoglutarate | 0.9730 | 1.0055 | 1.1022 | 0.9152 |
| aspartate | 1.1335 | 0.9057 | 1.0654 | 0.9238 |
| beta-hydroxyisovalerate | 0.9461 | 1.0690 | 0.8913 | 1.0783 |
| creatine phosphate | 0.7702 | 1.4455 | 0.4909 | 1.2090 |
| cytidine 5^-monophospho-N-acetylneuraminic acid | 1.0479 | 0.9960 | 0.9817 | 0.9809 |
| dehydroascorbate | 1.0007 | 0.9908 | 1.1264 | 0.8833 |
| dimethylmalonic acid | 1.0423 | 0.9521 | 1.0687 | 0.9017 |
| erythronate* | 0.9748 | 0.9266 | 1.1779 | 0.9268 |
| ethylmalonate | 0.8639 | 1.0788 | 0.9015 | 1.1289 |
| fructose | 0.9246 | 1.0062 | 1.0649 | 0.9941 |
| fructose-6-phosphate | 0.9810 | 0.8918 | 1.2247 | 0.9136 |
| fumarate | 0.9481 | 0.9649 | 1.1249 | 0.9601 |
| gluconate | 1.0344 | 0.9052 | 1.2631 | 0.8134 |
| glucosamine-6-phosphate | 1.0205 | 0.9774 | 1.1250 | 0.8825 |
| glucose | 0.8721 | 0.9799 | 1.1465 | 0.9881 |
| glucose 6-phosphate | 1.0269 | 0.8667 | 1.2163 | 0.9101 |
| glucuronate | 0.8180 | 1.0297 | 1.0322 | 1.0936 |
| glutarate (pentanedioate) | 0.9801 | 0.9366 | 1.2003 | 0.8885 |
| glycerate | 0.9179 | 1.0013 | 1.1354 | 0.9350 |
| glycerophosphoethanolamine | 1.1408 | 0.8451 | 1.2996 | 0.7515 |
| glycerophosphoglycerol | 1.0937 | 0.9250 | 1.1224 | 0.8800 |
| glycerophosphoinositol* | 1.2160 | 0.7503 | 1.3890 | 0.7029 |
| glycerophosphorylcholine (GPC) | 1.4331 | 0.8034 | 1.1881 | 0.6541 |
| gulonic acid* | 0.9905 | 0.9096 | 1.4215 | 0.6886 |
| hypotaurine | 0.8453 | 1.0169 | 1.2722 | 0.8442 |
| inositol 1-phosphate (I1P) | 1.2251 | 0.8303 | 1.1259 | 0.8681 |
| isocitrate | 0.7864 | 0.8762 | 1.3332 | 0.9929 |
| mannose | 1.1203 | 0.8639 | 1.0093 | 1.0385 |
| mannose-6-phosphate | 1.0174 | 0.8650 | 1.2440 | 0.8927 |
| methylphosphate | 0.9875 | 1.0768 | 1.1434 | 0.7812 |
| methylsuccinate | 0.8880 | 0.8786 | 1.2474 | 0.9871 |
| myo-inositol | 1.1586 | 0.8534 | 1.2418 | 0.7844 |
| N-acetylalanine | 1.1147 | 0.8672 | 1.2071 | 0.8419 |
| N-acetylaspartate (NAA) | 2.4901 | 0.3681 | 0.9140 | 0.4930 |
| N-acetyl-glucosamine 1-phosphate | 0.8505 | 1.0770 | 0.9478 | 1.0964 |
| N-acetylglucosamine 6-phosphate | 0.8242 | 1.0738 | 0.9472 | 1.1237 |
| N-acetylneuraminate | 1.1042 | 0.9065 | 1.1707 | 0.8434 |
| N-acetylserine | 1.0439 | 0.9664 | 1.0645 | 0.9349 |
| N-glycolylneuraminate | 1.0737 | 0.9421 | 1.0816 | 0.9191 |
| N-palmitoyl-sphingosine | 1.0151 | 1.0379 | 0.9678 | 0.9764 |
| oleoyl-linoleoyl-glycerophosphoinositol (1) | 0.9929 | 0.9304 | 1.0521 | 1.0324 |
| orotate | 0.7529 | 1.1994 | 0.5235 | 1.4683 |
| orotidine | 0.8589 | 1.0267 | 1.0753 | 1.0181 |
| palmitoyl-arachidonoyl-glycerophosphocholine (1)* | 1.0931 | 1.0620 | 0.8312 | 1.0177 |
| palmitoyl-arachidonoyl-glycerophosphocholine (2)* | 1.0027 | 1.0329 | 0.9020 | 1.0586 |
| palmitoyl-linoleoyl-glycerophosphocholine (1)* | 0.9925 | 1.0073 | 0.9436 | 1.0547 |
| palmitoyl-linoleoyl-glycerophosphocholine (2)* | 0.9406 | 0.9745 | 1.0086 | 1.0721 |
| palmitoyl-linoleoyl-glycerophosphoinositol (1)* | 1.0166 | 0.9043 | 1.0610 | 1.0321 |
| palmitoyl-oleoyl-glycerophosphocholine (1)* | 0.9368 | 1.0653 | 0.9061 | 1.0758 |
| palmitoyl-oleoyl-glycerophosphoglycerol (1) | 1.0188 | 1.0220 | 0.9990 | 0.9598 |
| palmitoyl-oleoyl-glycerophosphoglycerol (2) | 0.9972 | 1.0112 | 0.9609 | 1.0289 |
| palmitoyl-palmitoyl-glycerophosphocholine (1)* | 1.0211 | 0.9870 | 0.9487 | 1.0474 |
| palmitoyl-palmitoyl-glycerophosphocholine (2)* | 0.9601 | 0.9757 | 1.0119 | 1.0504 |
| palmitoyl sphingomyelin (d18:1/16:0) | 1.0739 | 1.0275 | 0.9751 | 0.9293 |
| p-cresol sulfate | 0.0369 | 1.3509 | 0.1466 | 2.1810 |
| phenyllactate (PLA) | 1.1720 | 0.9340 | 0.9986 | 0.9251 |
| phosphoethanolamine | 1.1255 | 0.9715 | 1.0445 | 0.8778 |
| pimelate (heptanedioate) | 0.7980 | 0.9244 | 1.2863 | 0.9755 |
| pyruvate | 0.8950 | 1.1169 | 0.9689 | 0.9914 |
| quinolinate | 0.9857 | 0.8583 | 1.1496 | 1.0223 |
| ribonate | 1.2143 | 0.8541 | 0.9593 | 1.0173 |
| ribose | 1.0541 | 0.8554 | 1.2103 | 0.9050 |
| ribose 1-phosphate | 0.9397 | 0.9432 | 1.0895 | 1.0272 |
| ribose 5-phosphate | 1.0484 | 0.8612 | 1.3343 | 0.8212 |
| serine | 1.0346 | 0.9934 | 1.0361 | 0.9411 |
| sphingomyelin (d18:1/18:1, d18:2/18:0) | 0.9563 | 1.1811 | 0.8592 | 0.9717 |
| sphingomyelin (d18:1/20:1, d18:2/20:0)* | 1.1257 | 1.0151 | 0.9547 | 0.9340 |
| sphingomyelin (d18:1/22:1, d18:2/22:0, d16:1/24:1)* | 0.9772 | 1.0621 | 1.0055 | 0.9445 |
| sphingomyelin (d18:1/24:1, d18:2/24:0)* | 1.0043 | 0.9517 | 1.0625 | 0.9886 |
| sphingomyelin (d18:2/16:0, d18:1/16:1)* | 1.0481 | 1.0905 | 0.8328 | 1.0233 |
| stearoyl-arachidonoyl-glycerophosphocholine (1)* | 1.1796 | 1.0945 | 0.8199 | 0.9166 |
| stearoyl-arachidonoyl-glycerophosphocholine (2)* | 1.0336 | 1.0348 | 0.9445 | 0.9870 |
| stearoyl-arachidonoyl-glycerophosphoethanolamine (1)* | 1.0322 | 0.9894 | 1.0025 | 0.9812 |
| stearoyl-arachidonoyl-glycerophosphoinositol (1)* | 1.0754 | 0.9697 | 1.0354 | 0.9327 |
| stearoyl-arachidonoyl-glycerophosphoinositol (2) | 0.9619 | 0.8653 | 1.2744 | 0.9105 |
| stearoyl-linoleoyl-glycerophosphocholine (1)* | 0.9306 | 0.9627 | 1.1296 | 0.9731 |
| stearoyl-linoleoyl-glycerophosphocholine (2)* | 1.0040 | 0.9681 | 1.0873 | 0.9451 |
| stearoyl-linoleoyl-glycerophosphoethanolamine (1)* | 0.9311 | 0.9503 | 1.0887 | 1.0275 |
| stearoyl sphingomyelin (d18:1/18:0) | 1.0530 | 1.0387 | 0.9543 | 0.9624 |
| succinate | 0.9515 | 0.9353 | 1.0741 | 1.0412 |
| threonate | 0.8980 | 0.9968 | 1.1103 | 0.9825 |
| tricarballylate | 0.7510 | 0.7900 | 1.3565 | 1.0976 |
| xanthine | 1.3099 | 0.0481 | 2.7599 | 0.0398 |
Factors:
| F1 | Treament:Antibiotics | Exposure:Air |
| F2 | Treament:Antibiotics | Exposure:Ozone |
| F3 | Treament:Water | Exposure:Air |
| F4 | Treament:Water | Exposure:Ozone |
