Data for Targeted Sphingolipid analysis of human Fibroblasts silenced for or overexpressing GOLPH3 (Study ST001672)
(Analysis AN002730)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 |
|---|---|---|---|
| C14_cer | 0.6205 | 1.3179 | 1.0616 |
| C14HexosylCer | 0.8522 | 1.0135 | 1.1342 |
| C14Lact-Cer | NA | NA | NA |
| C14-SM | 0.9151 | 1.0052 | 1.0797 |
| C16_cer | 0.5787 | 1.4047 | 1.0166 |
| C16HexosylCer | 0.7463 | 1.1725 | 1.0812 |
| C16Lact-Cer | 1.2254 | 0.7668 | 1.0078 |
| C16-SM | 0.9209 | 1.0482 | 1.0309 |
| C18_1_cer | 0.6299 | 1.1662 | 1.2039 |
| C18_1HexosylCer | 0.9456 | 1.0800 | 0.9744 |
| C18_1Lact-Cer | NA | NA | NA |
| C18_1-SM | 0.9224 | 0.9701 | 1.1075 |
| C18_cer | 0.5854 | 1.2128 | 1.2018 |
| C18HexosylCer | 0.8922 | 1.1859 | 0.9219 |
| C18Lact-Cer | 1.1287 | 0.8358 | 1.0355 |
| C18-SM | 1.0136 | 1.0141 | 0.9722 |
| C20_1_cer | 0.6370 | 1.1550 | 1.2081 |
| C20_1HexosylCer | 0.9720 | 1.0449 | 0.9831 |
| C20_1Lact-Cer | NA | NA | NA |
| C20_1-SM | 0.7713 | 1.2468 | 0.9819 |
| C20_cer | 0.5947 | 1.1712 | 1.2341 |
| C20HexosylCer | 0.8073 | 1.3946 | 0.7981 |
| C20Lact-Cer | NA | NA | 1.0000 |
| C20-SM | NA | 1.0000 | NA |
| C22_1_cer | 0.5991 | 1.2136 | 1.1874 |
| C22_1HexosylCer | 0.8481 | 1.2179 | 0.9340 |
| C22_1Lact-Cer | 0.9931 | 1.0289 | 0.9780 |
| C22_1-SM | 0.9194 | 1.0791 | 1.0016 |
| C22_cer | 0.6565 | 1.3016 | 1.0419 |
| C22HexosylCer | 0.7171 | 1.5027 | 0.7802 |
| C22Lact-Cer | 1.1093 | 1.0565 | 0.8343 |
| C22-SM | 0.9043 | 1.1943 | 0.9014 |
| C24_1_cer | 0.7344 | 1.2686 | 0.9970 |
| C24_1HexosylCer | 0.8324 | 1.2392 | 0.9284 |
| C24_1Lact-Cer | 1.1784 | 0.9420 | 0.8795 |
| C24_1-SM | 0.9904 | 1.0320 | 0.9776 |
| C24_cer | 0.9087 | 1.2481 | 0.8432 |
| C24HexosylCer | 0.8140 | 1.3931 | 0.7929 |
| C24Lact-Cer | 1.2948 | 0.8967 | 0.8085 |
| C24-SM | 0.9265 | 1.1423 | 0.9312 |
| C26_1_cer | 0.8917 | 1.2111 | 0.8972 |
| C26_1HexosylCer | 0.7495 | 1.3362 | 0.9143 |
| C26_1Lact-Cer | 1.1152 | 1.0018 | 0.8830 |
| C26_1-SM | 0.7957 | 1.2523 | 0.9519 |
| C26_cer | 1.0329 | 1.0914 | 0.8757 |
| C26HexosylCer | 0.8890 | 1.3135 | 0.7975 |
| C26Lact-Cer | 1.0975 | 0.9883 | 0.9142 |
| C26-SM | 0.8754 | 1.2325 | 0.8921 |
Factors:
| F1 | Treatment:GOLPH3 overexpression |
| F2 | Treatment:GOLPH3 silencing |
| F3 | Treatment:no treatment |
