Data for (Study ST002377)

(Analysis AN003873)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2
1-Methyladenosine 1.1590 0.8410
1-Methylhistamine 0.9129 1.0871
1-Methylnicotinamide 0.9181 1.0819
2,4-Diaminobutyrate 0.7030 1.2970
3-Aminoisobutyrate 1.0323 0.9677
3-Methylhistidine 1.0324 0.9676
5-Aminoimidazole-4-carboxamide ribotide 1.0024 0.9976
5-Aminolevulinate 0.8808 1.1192
5-Hydroxyindoleacetate 0.6711 1.2631
5-Methyltetrahydrofolate 0.4270 1.5730
5-Methylthioadenosine 0.9572 1.0428
7,8-Dihydrobiopterin 1.0383 0.9617
Adenine 1.0241 0.9759
Adenosine 1.0397 0.9603
ADMA 0.8572 1.1428
Ala 0.9579 1.0421
Ala-Ala 0.7945 1.2055
Allantoin 0.9238 1.0762
alpha-Aminoadipate 1.2358 0.7642
alpha-Lipoamide 1.0287 0.9713
Alpha-Methylserine 0.8027 1.1973
Arg 0.8739 1.1261
Asn 0.8210 1.1790
Asp 0.8783 1.1217
beta-Ala 1.0973 0.9027
Betaine 0.6836 1.3164
Betaine aldehyde (+H2O) 0.8009 1.1991
Cadaverine 1.0298 0.8511
Carnitine 0.8423 1.1577
Carnosine 0.9417 1.0583
Choline 0.6943 1.3057
Citrulline 0.9382 1.0618
Creatine 0.9435 1.0565
Creatinine 0.9083 1.0917
Cyclohexylamine 1.0218 0.9782
Cys 0.9959 1.0041
Cystathionine 0.8501 1.1499
Cysteine-glutathione disulphide -Divalent 0.9723 1.0277
Cystine NA NA
Cytidine 1.2921 0.7079
Cytosine NA 1.0000
D-2-aminobutyrate 1.2394 0.7606
Dihydrouracil 0.9887 1.0113
Ethanolamine phosphate 0.9807 1.0193
GABA 0.8940 1.1060
gamma-Butyrobetaine 0.8457 1.1543
gamma-Glu-cys 0.8920 1.1080
gamma-Guanidinobutyrate 0.8245 1.1755
Gln 1.1326 0.8674
Glu 0.9671 1.0329
Glu-Glu 1.0208 0.9792
Glutathione(ox) 0.9623 1.0377
Glutathione(red) 0.9526 1.0474
Gly 0.9699 1.0301
Glycerophosphorylcholine 0.1810 1.8190
Gly-Gly 0.9078 1.0922
Gly-Leu 0.7847 1.2153
Guanidinoacetate 1.3500 0.6500
Guanidinosuccinate 0.9153 1.0847
Guanine 0.9312 1.0688
Guanosine 1.1386 0.8614
His 1.0311 0.9689
Histamine 0.9273 1.0727
Homoserine 0.8101 1.1899
Hydroxyproline 0.8419 1.1581
Hypotaurine 0.5348 1.4652
Hypoxanthine 0.8626 1.1374
Ile 0.9734 1.0266
Imidazole-4-acetate 0.9269 1.0914
Inosine 1.0436 0.9564
Isobutylamine 1.0358 0.9642
Kynurenine 0.9942 1.0058
Leu 0.9446 1.0554
Lys 1.0044 0.9956
Met 0.8996 1.1004
Methionine sulfoxide 0.8025 1.1975
N6,N6,N6-Trimethyllysine 0.9558 1.0442
N8-Acetylspermidine 1.0916 0.9084
N-Acetylglucosamine 0.9184 1.0816
N-Acetylglucosylamine 0.9789 1.0169
N-Acetylhistidine 0.8247 1.1753
N-Acetylornithine 0.9585 1.0415
N-Acetylputrescine 1.0000 NA
N-Acetylvaline 1.0658 0.9342
N-epsilon-Acetyllysine 0.9355 1.0645
N-gamma-Ethylglutamine 0.8694 1.1306
Nicotinamide 0.9141 1.0859
N-Methylalanine 1.2332 0.8134
N,N-Dimethylglycine 0.9797 1.0203
o-Acetylcarnitine 0.6865 1.3135
Ophthalmate 1.1414 0.8586
Ornithine 0.9778 1.0222
Phe 0.8836 1.1164
Phosphorylcholine 0.7886 1.2114
Pipecolate 1.0400 0.9600
Pro 0.9430 1.0570
Pterin 0.6764 1.2589
Purine 0.8560 1.1440
Putrescine(1,4-Butanediamine) 1.7715 0.2285
Pyridoxal 0.8916 1.1084
Pyridoxamine 0.8087 1.1913
Pyridoxamine 5^-phosphate 1.0130 0.9870
Riboflavin 1.0301 0.9699
Saccharopine 0.7384 1.2616
SAH 0.9301 1.0699
SAM+ 1.0836 0.9164
Sarcosine 1.1175 0.8825
SDMA 0.9464 1.0536
Ser 0.9875 1.0125
Serotonin 1.0099 0.9901
S-Lactoylglutathione 0.8384 1.1616
S-Methylmethionine 0.7717 1.2283
Spermidine 1.1992 0.8008
Spermine 1.0111 0.9889
Taurine 1.2093 0.7907
Taurocyamine 1.0067 0.9933
Thiamine 0.3642 1.6358
Thiamine monophosphate 0.4543 1.2183
Thr 0.9184 1.0816
Thymidine 0.9863 1.0137
Thymine 0.9969 1.0031
Trigonelline 0.9934 1.0039
Trimethylamine N-oxide 0.4861 1.5139
Trp 0.9681 1.0319
Tyr 0.9394 1.0606
Tyramine 1.1082 0.8918
Uracil 1.0085 0.9915
Urea 0.7984 1.2016
Uridine 0.9909 1.0091
Val 0.9532 1.0468
Xanthine 0.9762 1.0238
Xanthosine 1.1832 0.8168
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Factors:

F1Genotype:Pnpla7-knockout
F2Genotype:Wild-type
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