SIMPEL: Stable Isotope assisted Metabolomics for Pathway ELucidation
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The compound annotation file is a tab-delimited file containing five columns: 1. 'prefix' - corresponds to a bin number to be used as a unique identifier for each of the compounds. 2. 'polarity' whether the compound is to be searched against 'pos' ionization mode data or a 'neg' ionization mode data within the xcms_data. Note: Currently SIMPEL can only calculate m/z for +H and -H adducts. 3. 'rt' the retention time at which the compound is to be expected 4. 'formula' the chemical formula for which exact mass is to be calculated 5. 'Compound' name of the compound, which can also be used as a unique identifier. 6. 'poolsize' pool size of the compound (there can be multiple columns for this, one for each 'Category' being analyzed.
prefix | polarity | rt | formula | Compound | poolsize_WT | poolsize_GAT |
N051 | neg | 2.3 | C4H6O5 | D-(+)-Malicacid | 107.6774357 | 100.8139106 |
N052 | neg | 2.32 | C4H4O4 | Fumaricacid | 3.941062065 | 1.982880741 |
N054 | neg | 3.03 | C5H6O5 | 2-Oxoglutaricacid | 5.776163174 | 5.417510055 |
P114 | pos | 4.36 | C9H11NO2 | Phenylalanine | 0.402780834 | 0.435388632 |
P144 | pos | 9.21 | C4H9NO2 | Aminobutyricacid(GABA) | 2.839038954 | 2.155758333 |
P158 | pos | 10.29 | C5H9NO4 | Glutamicacid | 22.34015992 | 16.12680065 |
P163 | pos | 10.6 | C5H10N2O3 | Glutamine_Pos | 318.6346889 | 199.05037 |
P167 | pos | 10.71 | C4H8N2O3 | Asparagine_pos | 8.907678235 | 4.825643648 |
P168 | pos | 10.72 | C3H7NO3 | Serine | 13.46323843 | 7.533173869 |
P170 | pos | 10.95 | C4H7NO4 | Asparticacid_Pos | 15.38396859 | 7.120875352 |