Statistics Toolbox for Study: ST002998

Title: The role of gut microbiota in muscle mitochondria function, colon health, and sarcopenia: from clinical to bench

Select a dataset:

LC-MS NEGATIVE ION MODE (AN004924) LC-MS POSITIVE ION MODE (AN004925)

Run analyses on data in Study ST002998 Dataset: LC-MS NEGATIVE ION MODE

Metabolite structures and classes (all analyses combined)

• Pie chart of metabolite super classes
• Pie chart of metabolite main classes
• Pie chart of metabolite sub classes
• Molecular structure similarity analysis

Normalization and averaging

• Perform sample normalization / Show metabolite averages / Run cluster analysis
• Perform analyte scaling on data
• Create Relative log abundance plots

Univariate analysis

• Perform multi-condition dot plot analysis
• Perform Volcano plot analysis
• Perform ANOVA analysis

Clustering and correlation

• Perform hierarchial or heatmap cluster analysis
• Perform Clustered correlation analysis
• Perform Network analysis on correlated metabolites (mapped to classification)
• Perform Network analysis on correlated metabolites (mapped to fold-change)

Multivariate analysis

• Perform Principal component analysis
• Perform Linear discriminant analysis
• Perform Partial least-squares discriminant analysis (PLS-DA)

Classification and feature analysis

• Perform OPLS-DA and VIP projection
• Random Forest and VIP projection

MetaBatch Omic Browser (MD Anderson Cancer Center)

(Clustered Heat Maps, PCA+, UMAP, box plot, violin plot, and other visualizations)

• Load this study
• Load this analysis (AN004924)

MetENP: Metabolite enrichment and species-specific pathway annotation

• MetENP R package
• MetENP tutorial

Mapping metabolites to human biochemical pathways

• Not applicable (non-mammalian)