RefMet Compound Details

MW structure43616 (View MW Metabolite Database details)
RefMet name5-Hydroxy-tryptophan
Systematic name(2S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
Exact mass220.084793 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC11H12N2O3View other entries in RefMet with this formula
InChIKeyLDCYZAJDBXYCGN-VIFPVBQESA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassOrganic acids
Main ClassAmino acids and peptides
Sub ClassAmino acids
Pubchem CID439280
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving 5-Hydroxy-tryptophan

Rxn IDKEGG ReactionEnzyme
R02702 5-Hydroxy-L-tryptophan + Oxygen <=> 5-Hydroxy-N-formylkynurenine5-hydroxy-L-tryptophan:oxygen 2,3-dioxygenase (indole-decyclizing)
R02701 5-Hydroxy-L-tryptophan <=> Serotonin + CO25-Hydroxy-L-tryptophan decarboxy-lyase
R01814 Tetrahydrobiopterin + L-Tryptophan + Oxygen <=> 5-Hydroxy-L-tryptophan + Dihydrobiopterin + H2OL-Tryptophan,tetrahydrobiopterin:oxygen oxidoreductase (5-hydroxylating)

Table of KEGG human pathways containing 5-Hydroxy-tryptophan

Pathway IDHuman Pathway# of reactions
hsa00380 Tryptophan metabolism 3