RefMet Compound Details

MW structure37412 (View MW Metabolite Database details)
RefMet name5-Hydroxyindoleacetic acid
Systematic name2-(5-hydroxy-1H-indol-3-yl)acetic acid
SMILESc1cc2c(cc1O)c(CC(=O)O)c[nH]2   Run Tanimoto similarity search (with similarity coefficient >=0.6)
Exact mass191.058244 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC10H9NO3View other entries in RefMet with this formula
InChIInChI=1S/C10H9NO3/c12-7-1-2-9-8(4-7)6(5-11-9)3-10(13)14/h1-2,4-5,11-12H,3H2,(H,13,14)
InChIKeyDUUGKQCEGZLZNO-UHFFFAOYSA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassAlkaloids
Main ClassTryptophan alkaloids
Sub ClassIndoleacetic acids
Pubchem CID1826
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving 5-Hydroxyindoleacetic acid

Rxn IDKEGG ReactionEnzyme
R04904 5-Hydroxyindoleacetaldehyde + Oxygen + H2O <=> 5-Hydroxyindoleacetate + Hydrogen peroxide5-hydroxyindoleacetaldehyde:oxygen oxidoreductase
R04905 S-Adenosyl-L-methionine + 5-Hydroxyindoleacetate <=> S-Adenosyl-L-homocysteine + 5-MethoxyindoleacetateS-Adenosyl-L-methionine:N-acetylserotonin O-methyltransferase
R04903 5-Hydroxyindoleacetaldehyde + NAD+ + H2O <=> 5-Hydroxyindoleacetate + H+ + NADH5-Hydroxyindoleacetaldehyde:NAD+ oxidoreductase

Table of KEGG human pathways containing 5-Hydroxyindoleacetic acid

Pathway IDHuman Pathway# of reactions
hsa00380 Tryptophan metabolism 3
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