RefMet Compound Details

RefMet ID, RefMet name, exact mass and formula
RefMet ID	RM0136810
RefMet name	Biliverdin
Systematic name	biliverdin
Synonyms	PubChem Synonyms
Exact mass	582.247836 (neutral)	Calculate m/z: (Choose adduct) [M+H]+ [M+H-H2O]+ [M.]+ [M+2H]2+ [M+3H]3+ [M+4H]4+ [M+K]+ [M+2K]2+ [M+2K-H]+ [M+Na]+ [M+2Na]2+ [M+2Na-H]+ [M+Li]+ [M+2Li]2+ [M+NH4]+ [M.CH3]+ [M+Ag]+ [M+H+CH3OH]+ [M+H+CH3CN]+ [M+H+2CH3CN]+ [M+Na+CH3CN]+ [M.NaFormate+H]+ [M.NH4Formate+H]+ [M.TMSi]+ [M.tBuDMSi]+ [M+H-Hexose]+ [M+H-EtnP]+ [M+H-SerP]+ [M-H]- [M-H-H2O]- [M-CH3]- [M-2H]2- [M-3H]3- [M-4H]4- [M+Cl]- [M+OAc]- [M+Na-2H]- [M+K-2H]- [M.Formate]- [M.NaFormate-H]- [M.NH4Formate-H]- [M.F]- [M-H-Ser]- [M.HF2]- M(neutral)    View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
Formula	C33H34N4O6	View other entries in RefMet with this formula
Molecular descriptors
Molfile	50741 (Download molfile/View MW Metabolite Database details)
InChI	InChI=1S/C33H34N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-1 6(3)21(8-2)33(43)36-26/h7-8,13-15,35H,1-2,9-12H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-,28-15-
InChIKey	QBUVFDKTZJNUPP-BBROENKCSA-N	View other enantiomers/diastereomers of this metabolite in RefMet
SMILES	C=CC1=C(C)C(=O)N/C/1=C\c1c(C)c(CCC(=O)O)c(/C=C\2/C(=C(C)C(=N2)/C=C\2/C(=C(C=C)C(=O)N2)C)CCC(=O)O)[nH]1 Run Tanimoto similarity search (with similarity coefficient >=0.6)
Chemical/Biochemical Classification
Super Class	Organoheterocyclic compounds
Main Class	Bilirubins
Sub Class	Bilirubins
Distribution of Biliverdin in NMDR studies
Species	Plot Species distribution
Sample source	Plot Sample source(tissue) distribution
Platform	Platform (MS/NMR) used for detection
Chromatography	Chromatography methods used for detection
Studies	NMDR Studies reporting Biliverdin
External Links
Pubchem CID	5280353
ChEBI ID	17033
KEGG ID	C00500
HMDB ID	HMDB0001008
Spectral data for Biliverdin standards
MassBank(EU)	View MS spectra
Structural annotation level
Annotation level	1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving Biliverdin

Rxn ID	KEGG Reaction	Enzyme
R00311	Heme + 3 [Reduced NADPH---hemoprotein reductase] + 3 Oxygen <=> Biliverdin + CO + Fe2+ + 3 [Oxidized NADPH---hemoprotein reductase] + 3 H2O	protoheme,NADPH---hemoprotein reductase:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)
R02391	Bilirubin + NAD+ <=> Biliverdin + NADH + H+	Bilirubin:NAD+ oxidoreductase
R02393	Bilirubin + NADP+ <=> Biliverdin + NADPH + H+	Bilirubin:NADP+ oxidoreductase
R11579	Heme + 6 Reduced ferredoxin + 3 Oxygen + 6 H+ <=> Biliverdin + Fe2+ + CO + 6 Oxidized ferredoxin + 3 H2O	protoheme,reduced ferredoxin:oxygen oxidoreductase (alpha-methene-oxidizing, hydroxylating)
R12481	Bilirubin + Oxidised coenzyme F420-(gamma-Glu)n <=> Biliverdin + Reduced coenzyme F420-(gamma-Glu)n	Bilirubin + Oxidised coenzyme F420-(gamma-Glu)n <=> Biliverdin + Reduced coenzyme F420-(gamma-Glu)n

Table of KEGG human pathways containing Biliverdin

Pathway ID	Human Pathway	# of reactions
hsa01100	Metabolic pathways	4
hsa00860	Porphyrin metabolism	2
hsa00860	Porphyrin and chlorophyll metabolism	1