RefMet Compound Details

RefMet IDRM0126032
MW structure35465 (View MW Metabolite Database details)
RefMet nameCorticosterone
Systematic name11beta,21-dihydroxypregn-4-ene-3,20-dione
SMILESC[C@]12CCC(=O)C=C1CC[C@H]1[C@@H]3CC[C@H](C(=O)CO)[C@@]3(C)C[C@@H]([C@H]21)O   Run Tanimoto similarity search (with similarity coefficient >=0.6)
Sum CompositionST 21:3;O4 View other entries in RefMet with this sum composition
Exact mass346.214410 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC21H30O4View other entries in RefMet with this formula
InChIInChI=1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-
2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1
InChIKeyOMFXVFTZEKFJBZ-HJTSIMOOSA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassSterol Lipids
Main ClassSteroids
Sub ClassC21 Steroids
Pubchem CID5753
ChEBI ID16827
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving Corticosterone

Rxn IDKEGG ReactionEnzyme
R03262 Corticosterone + 2 Reduced adrenal ferredoxin + Oxygen + 2 H+ <=> 18-Hydroxycorticosterone + 2 Oxidized adrenal ferredoxin + H2OCorticosterone,reduced-adrenal-ferredoxin:oxygen oxidoreductase (18-hydroxylating)
R03847 Corticosterone + NAD+ <=> 11-Dehydrocorticosterone + NADH + H+Corticosterone:NAD+ 11-oxidoreductase
R03848 Corticosterone + NADP+ <=> 11-Dehydrocorticosterone + NADPH + H+Corticosterone:NADP+ 11-oxidoreductase
R03849 11beta-Hydroxyprogesterone + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Corticosterone + [Oxidized NADPH---hemoprotein reductase] + H2O11beta-hydroxyprogesterone,NADPH-hemoprotein reductase:oxygen oxidoreductase (21-hydroxylating)
R03851 11-Deoxycorticosterone + 2 Reduced ferredoxin + Oxygen + 2 H+ <=> Corticosterone + 2 Oxidized ferredoxin + H2O11-deoxycorticosterone,reduced ferredoxin:oxygen oxidoreductase (11-hydroxylating)

Table of KEGG human pathways containing Corticosterone

Pathway IDHuman Pathway# of reactions
hsa00140 Steroid hormone biosynthesis 5
  logo