RefMet Compound Details

MW structure37773 (View MW Metabolite Database details)
RefMet nameGMP
Systematic name{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid
SMILESC([C@@H]1[C@H]([C@H]([C@H](n2cnc3c2nc(N)[nH]c3=O)O1)O)O)OP(=O)(O)O   Run Tanimoto similarity search (with similarity coefficient >=0.6)
Exact mass363.058003 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC10H14N5O8PView other entries in RefMet with this formula
InChIInChI=1S/C10H14N5O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3
,11,13,14,18)/t3-,5-,6-,9-/m1/s1
InChIKeyRQFCJASXJCIDSX-UUOKFMHZSA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassNucleic acids
Main ClassPurines
Sub ClassPurine rNMP
Pubchem CID135398631
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving GMP

Rxn IDKEGG ReactionEnzyme
R00328 GDP + H2O <=> GMP + OrthophosphateGDP phosphohydrolase
R00332 ATP + GMP <=> ADP + GDPATP:GMP phosphotransferase
R00426 GTP + H2O <=> GMP + DiphosphateGTP diphosphohydrolase (diphosphate-forming)
R01134 IMP + Ammonia + NADP+ <=> GMP + NADPH + H+inosine-5'-phosphate:NADP+ oxidoreductase (aminating)
R01227 GMP + H2O <=> Guanosine + Orthophosphateguanosine 5'-monophosphate phosphohydrolase
R01228 ATP + Guanosine <=> ADP + GMPATP:guanosine 5'-phosphotransferase
R01229 GMP + Diphosphate <=> Guanine + 5-Phospho-alpha-D-ribose 1-diphosphateGMP:diphosphate 5-phospho-alpha-D-ribosyltransferase
R01230 ATP + Xanthosine 5'-phosphate + Ammonia <=> AMP + Diphosphate + GMPXanthosine-5'-phosphate:ammonia ligase (AMP-forming)
R01231 ATP + Xanthosine 5'-phosphate + L-Glutamine + H2O <=> AMP + Diphosphate + GMP + L-GlutamateXanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming)
R01234 3',5'-Cyclic GMP + H2O <=> GMPGuanosine 3',5'-cyclic phosphate 5'-nucleotidohydrolase

Table of KEGG human pathways containing GMP

Pathway IDHuman Pathway# of reactions
hsa00230 Purine metabolism 9
hsa01100 Metabolic pathways 3
hsa01232 Nucleotide metabolism 2
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