RefMet Compound Details

RefMet ID, RefMet name, exact mass and formula
RefMet ID	RM0033601
RefMet name	GMP
Systematic name	{[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}phosphonic acid
Synonyms	PubChem Synonyms
Exact mass	363.058003 (neutral)	Calculate m/z: (Choose adduct) [M+H]+ [M+H-H2O]+ [M.]+ [M+2H]2+ [M+3H]3+ [M+4H]4+ [M+K]+ [M+2K]2+ [M+2K-H]+ [M+Na]+ [M+2Na]2+ [M+2Na-H]+ [M+Li]+ [M+2Li]2+ [M+NH4]+ [M.CH3]+ [M+Ag]+ [M+H+CH3OH]+ [M+H+CH3CN]+ [M+H+2CH3CN]+ [M+Na+CH3CN]+ [M.NaFormate+H]+ [M.NH4Formate+H]+ [M.TMSi]+ [M.tBuDMSi]+ [M+H-Hexose]+ [M+H-EtnP]+ [M+H-SerP]+ [M-H]- [M-H-H2O]- [M-CH3]- [M-2H]2- [M-3H]3- [M-4H]4- [M+Cl]- [M+OAc]- [M+Na-2H]- [M+K-2H]- [M.Formate]- [M.NaFormate-H]- [M.NH4Formate-H]- [M.F]- [M-H-Ser]- [M.HF2]- M(neutral)    View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
Formula	C10H14N5O8P	View other entries in RefMet with this formula
Molecular descriptors
Molfile	37773 (Download molfile/View MW Metabolite Database details)
InChI	InChI=1S/C10H14N5O8P/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,16-17H,1H2,(H2,19,20,21)(H3 ,11,13,14,18)/t3-,5-,6-,9-/m1/s1
InChIKey	RQFCJASXJCIDSX-UUOKFMHZSA-N	View other enantiomers/diastereomers of this metabolite in RefMet
SMILES	C([C@@H]1[C@H]([C@H]([C@H](n2cnc3c2nc(N)[nH]c3=O)O1)O)O)OP(=O)(O)O Run Tanimoto similarity search (with similarity coefficient >=0.6)
Chemical/Biochemical Classification
Super Class	Nucleic acids
Main Class	Purines
Sub Class	Purine rNMP
Distribution of GMP in NMDR studies
Species	Plot Species distribution
Sample source	Plot Sample source(tissue) distribution
Platform	Platform (MS/NMR) used for detection
Chromatography	Chromatography methods used for detection
Studies	NMDR Studies reporting GMP
External Links
Pubchem CID	135398631
ChEBI ID	17345
KEGG ID	C00144
HMDB ID	HMDB0001397
Chemspider ID	6545
MetaCyc ID	GMP
Spectral data for GMP standards
NP-MRD ID(NMR)	View NMR spectra
MassBank(EU)	View MS spectra
Structural annotation level
Annotation level	1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving GMP

Rxn ID	KEGG Reaction	Enzyme
R00328	GDP + H2O <=> GMP + Orthophosphate	GDP phosphohydrolase
R00332	ATP + GMP <=> ADP + GDP	ATP:GMP phosphotransferase
R00426	GTP + H2O <=> GMP + Diphosphate	GTP diphosphohydrolase (diphosphate-forming)
R01134	IMP + Ammonia + NADP+ <=> GMP + NADPH + H+	inosine-5'-phosphate:NADP+ oxidoreductase (aminating)
R01227	GMP + H2O <=> Guanosine + Orthophosphate	guanosine 5'-monophosphate phosphohydrolase
R01228	ATP + Guanosine <=> ADP + GMP	ATP:guanosine 5'-phosphotransferase
R01229	GMP + Diphosphate <=> Guanine + 5-Phospho-alpha-D-ribose 1-diphosphate	GMP:diphosphate 5-phospho-alpha-D-ribosyltransferase
R01230	ATP + Xanthosine 5'-phosphate + Ammonia <=> AMP + Diphosphate + GMP	Xanthosine-5'-phosphate:ammonia ligase (AMP-forming)
R01231	ATP + Xanthosine 5'-phosphate + L-Glutamine + H2O <=> AMP + Diphosphate + GMP + L-Glutamate	Xanthosine-5'-phosphate:L-glutamine amido-ligase (AMP-forming)
R01234	3',5'-Cyclic GMP + H2O <=> GMP	Guanosine 3',5'-cyclic phosphate 5'-nucleotidohydrolase

Table of KEGG human pathways containing GMP

Pathway ID	Human Pathway	# of reactions
hsa00230	Purine metabolism	9
hsa01100	Metabolic pathways	3
hsa01232	Nucleotide metabolism	2