RefMet Compound Details
RefMet ID | RM0153610 | |
---|---|---|
MW structure | 323 (View MW Metabolite Database details) | |
RefMet name | Ketoisovaleric acid | |
Systematic name | 3-methyl-2-oxo-butanoic acid | |
SMILES | CC(C)C(=O)C(=O)O Run Tanimoto similarity search (with similarity coefficient >=0.6) | |
Sum Composition | FA 5:1;O | View other entries in RefMet with this sum composition |
Exact mass | 116.047345 (neutral) |
Table of KEGG reactions in human pathways involving Ketoisovaleric acid
Rxn ID | KEGG Reaction | Enzyme |
---|---|---|
R01214 | L-Valine + 2-Oxoglutarate <=> 3-Methyl-2-oxobutanoic acid + L-Glutamate | L-Valine:2-oxoglutarate aminotransferase |
R01215 | L-Valine + Pyruvate <=> 3-Methyl-2-oxobutanoic acid + L-Alanine | L-Valine:pyruvate aminotransferase |
R01434 | L-Valine + H2O + NAD+ <=> 3-Methyl-2-oxobutanoic acid + Ammonia + NADH + H+ | L-valine:NAD+ oxidoreductase(deaminating) |
R01701 | 3-Methyl-2-oxobutanoic acid + Enzyme N6-(lipoyl)lysine <=> [Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine + CO2 | 3-methyl-2-oxobutanoate:[dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-2-methylpropanoylating) |
Table of KEGG human pathways containing Ketoisovaleric acid
Pathway ID | Human Pathway | # of reactions |
---|---|---|
hsa01100 | Metabolic pathways | 3 |
hsa00280 | Valine, leucine and isoleucine degradation | 2 |
hsa00290 | Valine, leucine and isoleucine biosynthesis | 1 |
hsa00770 | Pantothenate and CoA biosynthesis | 1 |
hsa01210 | 2-Oxocarboxylic acid metabolism | 1 |
hsa01230 | Biosynthesis of amino acids | 1 |