Summary of Study ST001750
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001122. The data can be accessed directly via it's Project DOI: 10.21228/M8P686 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST001750 |
Study Title | Gut microbiome influence on metabolic 1 disease in HIV and high-risk populations |
Study Summary | Poor metabolic health, characterized by insulin resistance and dyslipidemia, is higher in people living with HIV (PLWH) and has been linked with inflammation, anti-retroviral therapy (ART) drugs, and ART-associated lipodystrophy (LD). Metabolic disease is associated with gut microbiome composition outside the context of HIV but has not been deeply explored in HIV infection nor in high-risk men who have sex with men (HR-MSM), who have a highly altered gut microbiome composition. Furthermore, the contribution of increased bacterial translocation and associated systemic inflammation that has been described in HIV-positive and HR-MSM individuals has not been explored. We used a multi-omic approach to explore relationships between gut microbes, immune phenotypes, diet, and metabolic health across ART-treated PLWH with and without LD; untreated PLWH; and HR-MSM. For PLWH on ART, we further explored associations with the plasma metabolome. |
Institute | University of Colorado Anschutz Medical Campus |
Last Name | Reisdorph |
First Name | Nichole |
Address | 12850 East Montview Blvd, Aurora, CO, 80045, USA |
nichole.reisdorph@cuanschutz.edu | |
Phone | 303-724-9234 |
Submit Date | 2021-04-24 |
Raw Data Available | Yes |
Raw Data File Type(s) | d |
Analysis Type Detail | LC-MS |
Release Date | 2021-05-04 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Mammal; Subject species: Homo sapiens (Factor headings shown in green)
mb_sample_id | local_sample_id | Sample_Type | Lipodystrophy | HIV_status | Antiviral_Treatment |
---|---|---|---|---|---|
SA163875 | 9_mouse | Humanized mouse | - | Negative | No |
SA163876 | 5_mouse | Humanized mouse | - | Negative | No |
SA163877 | 4_mouse | Humanized mouse | - | Negative | No |
SA163878 | 2_mouse | Humanized mouse | - | Negative | No |
SA163879 | 6_mouse | Humanized mouse | - | Positive | No |
SA163880 | 10_mouse | Humanized mouse | - | Positive | No |
SA163881 | 3_mouse | Humanized mouse | - | Positive | Yes |
SA163882 | 7_mouse | Humanized mouse | - | Positive | Yes |
SA163831 | 57 | Human | NO | Positive | Yes |
SA163832 | DM19 | Human | NO | Positive | Yes |
SA163833 | 40 | Human | NO | Positive | Yes |
SA163834 | DM003 | Human | NO | Positive | Yes |
SA163835 | DM034 | Human | NO | Positive | Yes |
SA163836 | DM002 | Human | NO | Positive | Yes |
SA163837 | 9 | Human | NO | Positive | Yes |
SA163838 | 128 | Human | NO | Positive | Yes |
SA163839 | 112 | Human | NO | Positive | Yes |
SA163840 | 36 | Human | NO | Positive | Yes |
SA163841 | DM032 | Human | NO | Positive | Yes |
SA163842 | 19 | Human | NO | Positive | Yes |
SA163843 | 30 | Human | NO | Positive | Yes |
SA163844 | 21 | Human | NO | Positive | Yes |
SA163845 | DM052 | Human | NO | Positive | Yes |
SA163846 | 23 | Human | NO | Positive | Yes |
SA163847 | DM036 | Human | NO | Positive | Yes |
SA163848 | 29 | Human | NO | Positive | Yes |
SA163849 | 27 | Human | NO | Positive | Yes |
SA163850 | 26 | Human | NO | Positive | Yes |
SA163851 | 145 | Human | YES | Positive | Yes |
SA163852 | 146 | Human | YES | Positive | Yes |
SA163853 | 152 | Human | YES | Positive | Yes |
SA163854 | 166 | Human | YES | Positive | Yes |
SA163855 | 133 | Human | YES | Positive | Yes |
SA163856 | 167 | Human | YES | Positive | Yes |
SA163857 | 157 | Human | YES | Positive | Yes |
SA163858 | 156 | Human | YES | Positive | Yes |
SA163859 | 131 | Human | YES | Positive | Yes |
SA163860 | 45 | Human | YES | Positive | Yes |
SA163861 | 55 | Human | YES | Positive | Yes |
SA163862 | 37 | Human | YES | Positive | Yes |
SA163863 | 132 | Human | YES | Positive | Yes |
SA163864 | 20 | Human | YES | Positive | Yes |
SA163865 | 22 | Human | YES | Positive | Yes |
SA163866 | 69 | Human | YES | Positive | Yes |
SA163867 | 25 | Human | YES | Positive | Yes |
SA163868 | 130 | Human | YES | Positive | Yes |
SA163869 | 72 | Human | YES | Positive | Yes |
SA163870 | 119 | Human | YES | Positive | Yes |
SA163871 | 106 | Human | YES | Positive | Yes |
SA163872 | 79 | Human | YES | Positive | Yes |
SA163873 | 80 | Human | YES | Positive | Yes |
SA163874 | 104 | Human | YES | Positive | Yes |
SA163883 | 1_mouse | PBS Control | - | - | - |
SA163884 | 8_mouse | PBS Control | - | - | - |
Showing results 1 to 54 of 54 |