Summary of Study ST001319
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000896. The data can be accessed directly via it's Project DOI: 10.21228/M8VX0Z This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST001319 |
Study Title | Pre-treatment L-Carnitine Pharmacometabolomics in Sepsis (CaPS) Patients |
Study Type | multiple timepoints; patients with severe sepsis or septic shock treated with varying doses of L-carnitine or a saline placebo |
Study Summary | phase II study of L-carnitine infusion for the treatment of vasopressor-dependent shock |
Institute | University of Michigan |
Laboratory | Stringer NMR Metabolomics Laboratory |
Last Name | McHugh |
First Name | Cora |
Address | 428 Church St, Ann Arbor, MI, 48103, USA |
NMRmetabolomics@umich.edu | |
Phone | 7343530164 |
Submit Date | 2020-02-07 |
Num Groups | 4 |
Total Subjects | 228 |
Num Males | 128 |
Num Females | 100 |
Publications | This submission is Phase II: https://www.ncbi.nlm.nih.gov/pubmed/30646314 doi: 10.1001/jamanetworkopen.2018.6076 Earlier Phase I: Metabolomics Workbench: doi: 10.21228/M8VM2M https://www.ncbi.nlm.nih.gov/pubmed/23851424 doi: 10.1177/0148607113495414 |
Raw Data Available | Yes |
Raw Data File Type(s) | fid |
Analysis Type Detail | NMR |
Release Date | 2020-09-10 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
NMR:
NMR ID: | NM000161 |
Analysis ID: | AN002195 |
Instrument Name: | Varian 11.74T |
Instrument Type: | FT-NMR |
NMR Experiment Type: | 1D-1H |
NMR Comments: | Arrayed for water saturation frequency and 90deg. pulse width for each sample. Varian (now Agilent, Inc., Santa Clara, CA) 11.74 Tesla (500 MHz) NMR spectrometer |
Spectrometer Frequency: | 500 MHz |
NMR Probe: | 5-mm Agilent “One-probe |
NMR Solvent: | D20 |
NMR Tube Size: | 5mm |
Shimming Method: | Auto shim (gradient shimming) |
Pulse Sequence: | 1 H,1 H-NOESY (commonly referred to as a 1D-NOESY or METNOESY) |
Water Suppression: | saturation at 80 Hz induced field strength |
Pulse Width: | ~5.5ms, arrayed for in each sample |
Temperature: | 25 |
Number Of Scans: | 32 |