Summary of Study ST001413
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000969. The data can be accessed directly via it's Project DOI: 10.21228/M8FD5Z This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST001413 |
Study Title | Metabolomic and Transcriptomic Signatures of Prenatal Excessive Methionine in Mice |
Study Type | MS Analysis |
Study Summary | Micronutrients are key regulators of prenatal one-carbon (C1) metabolism. We show here that prenatal excessive methionine (MET), a principal micronutrient and methyl-donor, produces in early life stages significant changes in the components of brain C1 pathways and other metabolic pathways including glutamate transmission, mitochondrial function, and lipid metabolism. |
Institute | University of California, Irvine |
Department | Department of Pharmaceutical Sciences and Department of Computer Science |
Laboratory | Amal Alachkar Group. Pierre Baldi Group |
Last Name | Chen |
First Name | Siwei |
Address | 66304 Verano Place Rd. South |
siweic@uci.edu | |
Phone | 2066585923 |
Submit Date | 2020-06-24 |
Num Groups | 4 |
Total Subjects | 28 |
Num Males | 28 |
Raw Data Available | Yes |
Raw Data File Type(s) | wiff |
Analysis Type Detail | LC-MS |
Release Date | 2020-07-24 |
Release Version | 1 |
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Project:
Project ID: | PR000969 |
Project DOI: | doi: 10.21228/M8FD5Z |
Project Title: | Metabolic and Transcriptomic Signatures of Prenatal Excessive Methionine in Mice |
Project Type: | MS Analysis |
Project Summary: | Micronutrients are key regulators of prenatal one-carbon (C1) metabolism. In this study, we show here that prenatal excessive methionine (MET), a principal micronutrient and methyl-donor, produces in early life stages significant changes in the components of brain C1 pathways and other metabolic pathways including glutamate transmission, mitochondrial function, and lipid metabolism. |
Institute: | University of California, Irvine |
Department: | Department of Pharmaceutical Sciences, School of Medicine; Department of Computer Science, School of Information and Computer Sciences |
Laboratory: | Amal Alachkar Group; Pierre Baldi Group |
Last Name: | Chen |
First Name: | Siwei |
Address: | 66304 Verano Place Rd. South |
Email: | siweic@uci.edu |
Phone: | 2066585923 |