Summary of Study ST001616
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001039. The data can be accessed directly via it's Project DOI: 10.21228/M8D400 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST001616 |
Study Title | Unique metabolomic profile of skeletal muscle in chronic limb threatening ischemia (aqueous phase samples ) |
Study Type | NMR |
Study Summary | This project is focused on a cross-sectional analysis of non-PAD controls and CLTI patients undergoing either a vascular intervention or undergoing limb amputation was performed and involved a detailed assessment of the limb muscle metabolome using HR-MAS and solution state NMR spectroscopy. It was hypothesized that patients undergoing limb amputation would present with altered muscle metaolite features compared with non-PAD controls. |
Institute | University of Florida |
Department | Applied Physiology and Kinesiology |
Laboratory | Rm 42 and Rm 43 |
Last Name | Ryan |
First Name | Terence |
Address | University of Florida, Applied Physiology and Kinesiology, 1864 stadium RD, Gainesville, FL 32611 |
ryant@ufl.edu | |
Phone | 352-294-1700 |
Submit Date | 2020-11-30 |
Num Groups | 3 |
Total Subjects | 30 |
Num Males | 25 |
Num Females | 5 |
Study Comments | PAD metabolomic study via NMR. A detailed assessment of the limb muscle metabolome using semi-solid and solution state NMR spectroscopy |
Publications | Journal of Clinical Medicine |
Raw Data Available | Yes |
Raw Data File Type(s) | fid |
Analysis Type Detail | NMR |
Release Date | 2021-05-30 |
Release Version | 1 |
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Project:
Project ID: | PR001039 |
Project DOI: | doi: 10.21228/M8D400 |
Project Title: | Unique metabolomic profile of skeletal muscle in chronic limb threatening ischemia |
Project Type: | NMR |
Project Summary: | This project is focused on a cross-sectional analysis of non-PAD controls and CLTI patients undergoing either a vascular intervention or undergoing limb amputation was performed and involved a detailed assessment of the limb muscle metabolome using HR-MAS and solution state NMR spectroscopy. It was hypothesized that patients undergoing limb amputation would present with altered muscle metabolite features compared with non-PAD controls. |
Institute: | University of Florida |
Department: | Applied Physiology and Kinesiology |
Laboratory: | Rm 42 and Rm 43 |
Last Name: | Ryan |
First Name: | Terence |
Address: | University of Florida, Applied Physiology and Kinesiology, 1864 stadium RD, Gainesville, FL 32611 |
Email: | ryant@ufl.edu |
Phone: | 352-294-1700 |
Funding Source: | National Institutes of Health and the National Heart, Lung, and Blood, Institute numbers R01-HL149704 (to T.E.R.) and R01-HL148597 (to S.T.S.); as well as the American Heart Association grant number 18CDA34110044 (to T.E.R.). A portion of this work was supported by pilot funds (awarded to T.E.R.) from The University of Florida Claude D. Pepper Older Americans Independence Center P30AG028740. (if applicable) |
Project Comments: | PAD metabolomic study via NMR. A detailed assessment of the limb muscle metabolome using semi-solid and solution state NMR spectroscopy. |
Publications: | Journal of Clinical Medicine |
Contributors: | Ram B. Khattri, Kyoungrae Kim, Trace Thome, Zachary R. Salyers, Kerri A. O’Malley, Scott A. Berceli, Salvatore T. Scali, Terence E. Ryan* |