Summary of Study ST000233
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000120. The data can be accessed directly via it's Project DOI: 10.21228/M82P4X This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST000233 |
Study Title | Metabolomics Reveals that Aryl Hydrocarbon Receptor Activation by Environmental Chemicals Induces Systemic Metabolic Dysfunction in Mice (Part II) |
Study Type | Time course |
Study Summary | 12 C57BL/6J male mice were acclimatized for 1 week and then divided into two groups and trained to eat dough pills. One group was control and the other was exposed to TCDF through the dough pills. The mice were treated for 5 days at a dosage .15μg of TCDF for a final concentration of 5μg/kg body weight. Also looked at were AHR-/- mice and they were treated the same way as the C57BL/6J mice. |
Institute | Pennsylvania State University |
Department | Department of Veterinary and Biomedical Sciences |
Last Name | Patterson |
First Name | Andrew |
Address | 101 Life Sciences, University Park, State college, 16802 |
rgn5011@psu.edu | |
Submit Date | 2015-07-07 |
Raw Data Available | Yes |
Raw Data File Type(s) | d |
Uploaded File Size | 256 MB |
Analysis Type Detail | GC-MS |
Release Date | 2015-08-14 |
Release Version | 1 |
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Sample Preparation:
Sampleprep ID: | SP000256 |
Sampleprep Summary: | - |
Sampleprep Protocol Filename: | GC_Sample_Prep.docx |
Processing Method: | Homogenization |
Extraction Method: | Methanol-Chloroform |
Extract Enrichment: | centerfugation |
Extract Cleanup: | bottom layer was dried with N2 gas, resuspended in MEOH/HCL and then hexane and saline, top layer was collected |
Sample Resuspension: | resuspended in hexane |
Sample Spiking: | C15:0 free acid and methy ester of C17:0 at 5 ?L |
Organ: | Liver |