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MB Sample ID: SA042894

Local Sample ID:CMC2008-0
Subject ID:SU000808
Subject Type:Human
Subject Species:Homo sapiens
Taxonomy ID:9606
Age Or Age Range:39-93 years
Weight Or Weight Range:55-130 KG
Gender:males and females
Human Race:Caucasian (C) and African American (AA)
Human Inclusion Criteria:Suspicion of or confirmed infection; two or more systemic infmammatory response syndrome criteria; hypotension requiring vasopressors despite volume resuscitation; a cumulative vasopressor index of 3 or more after 4 hours of administration; and a SOFA score of at least 5.
Human Exclusion Criteria:Age less than 18; greater than 16h after septic shock recognition; a Do Not Resuscitate order; or known inborn error of metaboloism.
Species Group:Human

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Collection:

Collection ID:CO000802
Collection Summary:Serum collected via existing intravenous or arterial catheter
Collection Protocol Comments:T0: collected before carnitine or placebo administration, T24: collected 24h after administration of L-carnitine or placebo (±4h), T48: collected 48h after administration of L-carnitine or placebo (±4h)
Sample Type:Blood serum
Collection Method:via existing intravenous or arterial catheter
Collection Frequency:1/timepoint, 3 collections/48h
Collection Time:T0: before administration, T24: 24h after administration (±4h), T48: 48h after administration (±4h)
Volumeoramount Collected:10mL
Storage Conditions:Initial RT then -80°C following processing (within 2h of collection)
Collection Vials:SST: Becton-Dickinson 10mL vacutainer Serum Separator tubes
Storage Vials:Sterile 1mL cryovials
Collection Tube Temp:RT
Additives:None
Blood Serum Or Plasma:Serum
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