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MB Sample ID: SA150510
| Local Sample ID: | DRB18invivo_8 |
| Subject ID: | SU001715 |
| Subject Type: | Mammal |
| Subject Species: | Mus musculus |
| Taxonomy ID: | 10090 |
| Age Or Age Range: | 4 weeks mice |
| Gender: | Male |
| Animal Animal Supplier: | Jackson Laboratory |
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Treatment:
| Treatment ID: | TR001728 |
| Treatment Summary: | Male NU/J nude mice of 3 to 4 weeks of age were purchased from The Jackson Laboratory and were fed with the Irradiated Teklad Global 19% protein rodent diet from Harlan Laboratories. The protocol for cell injection, treatment administration, weekly tumor measurement, animal euthanasia and final tumor measurements were performed as described previously (unless stated otherwise) (31). Tumor cell–injected mice were randomly divided into 2 groups: control group (n = 10) treated with PBS/DMSO (1:1, v/v) and 10 mg/kg (body weight) DRB18 treatment group (n = 10) dissolved in PBS/DMSO solution (1:1, v/v). Mice were given intraperitoneal injection with either PBS/DMSO vehicle or compound DRB18 (10 mg/kg) thrice a week for 5 weeks. |
| Treatment Protocol Filename: | prats1988_20201207_Invivo_collection_and_preparation_method.docx |
| Treatment: | Anticancer compound in xenograft tumors via i.p. |
| Treatment Compound: | Control (DMSO/PBS; 1:1 v/v) and DRB18 (10mg/kg body weight dissolved in DMSO/PBS; 1:1 v/v) |
| Treatment Route: | i.p. |
| Treatment Dose: | 10 mg/kg body weight |
| Treatment Dosevolume: | 100ul |
| Treatment Vehicle: | DMSO/PBS (1:1; v/v) |
