Summary of Study ST001181
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000793. The data can be accessed directly via it's Project DOI: 10.21228/M85T13 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001181 |
| Study Title | Child Health and Development Studies womb to breast cancer F0 metabolomics |
| Study Summary | We used high resolution metabolomics to understand DDT-induced alterations of in utero environment and potential health effects. This study measured endogenous metabolites in 397 maternal perinatal serum samples collected during 1959-1967 in the Child Health and Development Studies (CHDS) and assessed associations between metabolites and envrionmental chemical concentrations in maternal serum. |
| Institute | Emory University |
| Last Name | Hu |
| First Name | Xin |
| Address | Emory University Whitehead building (Rm 225), 615 Michael Street |
| xin.hu2@emory.edu | |
| Phone | 4047275091 |
| Submit Date | 2019-05-08 |
| Raw Data File Type(s) | raw(Thermo) |
| Analysis Type Detail | LC-MS |
| Release Date | 2019-10-11 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
| Analysis ID | AN001959 |
|---|---|
| Analysis type | MS |
| Chromatography type | Reversed phase |
| Chromatography system | Thermo Dionex Ultimate 3000 |
| Column | Thermo Accucore C18 (100 x 2.1mm,2.6um) |
| MS Type | ESI |
| MS instrument type | Orbitrap |
| MS instrument name | Thermo Q Exactive Orbitrap |
| Ion Mode | POSITIVE |
| Units | Peak area |
Chromatography:
| Chromatography ID: | CH001420 |
| Chromatography Summary: | Mass spectral data were collected with a 10-minute gradient on a Thermo QExactive coupled with Dionex Ultimate 3000 (Thermo Fisher, San Diego, CA) set to collect data from m/z 85 to 1275 in positive ionization mode at 70,000 resolution. Three technical replicates were run for each sample using dual chromatography measuring both polarities (positive and negative) with a C18 column (Higgins Analytical, 100x2.1mm, 5uL). The right pump controls the gradient with Solvent A as 100% water, Solvent B as 100% Acetontrile, and Solvent C as 98% water with 2% Formic Acid. The left pump is set up to wash (Acetonitrile with 2% Formic Acid) one of the columns while the other column is running the gradient. |
| Instrument Name: | Thermo Dionex Ultimate 3000 |
| Column Name: | Thermo Accucore C18 (100 x 2.1mm,2.6um) |
| Solvent A: | 100% water(A), 100% acetontrile(B), 100% water; 2% formic acid© |
| Solvent B: | 100% water(A), 100% acetontrile(B), 100% water; 2% formic acid(C) |
| Chromatography Type: | Reversed phase |
