Summary of Study ST001923

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001214. The data can be accessed directly via it's Project DOI: 10.21228/M8SH7V This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001923
Study TitleUrine-Based Metabolomics and Machine Learning Reveals Metabolites Associated with Renal Cell Carcinoma Progression
Study SummaryEvery year, hundreds of thousands of cases of renal carcinoma (RCC) are reported worldwide. Accurate staging of the disease is important for treatment and prognosis purposes; however, contemporary methods such as computerized tomography (CT) and biopsies are expensive and prone to sampling errors, respectively. As such, a non-invasive diagnostic assay for staging would be beneficial. This study aims to investigate urine metabolites as potential biomarkers to stage RCC. In the study, we identified a panel of such urine metabolites with machine learning techniques.
Institute
University of Georgia
DepartmentDepartment of Biochemistry and Molecular Biology
LaboratoryEdison Lab
Last NameBifarin
First NameOlatomiwa
Address315 Riverbend Rd, Athens, GA 30602
Emailolatomiwa.bifarin25@uga.edu
Phone757-405-4379
Submit Date2021-08-16
Num GroupsTwo
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2021-10-18
Release Version1
Olatomiwa Bifarin Olatomiwa Bifarin
https://dx.doi.org/10.21228/M8SH7V
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Combined analysis:

Analysis ID AN003125 AN003126
Analysis type MS MS
Chromatography type HILIC HILIC
Chromatography system Q Exactive HF Q Exactive HF
Column Waters ACQUITY UPLC BEH HILIC (75 x 2.1mm,1.7um) Waters ACQUITY UPLC BEH HILIC (75 x 2.1mm,1.7um)
MS Type ESI ESI
MS instrument type Orbitrap Orbitrap
MS instrument name Thermo Q Exactive HF hybrid Orbitrap Thermo Q Exactive HF hybrid Orbitrap
Ion Mode POSITIVE NEGATIVE
Units AU AU

Chromatography:

Chromatography ID:CH002310
Instrument Name:Q Exactive HF
Column Name:Waters ACQUITY UPLC BEH HILIC (75 x 2.1mm,1.7um)
Chromatography Type:HILIC
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