Summary of Study ST000462
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000355. The data can be accessed directly via it's Project DOI: 10.21228/M85C88 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST000462 |
| Study Title | CNS and peripheral metabolomics of calorie restriction in a mouse model of Alzheimer’s disease (part I) |
| Study Summary | This pilot metabolomic study will evaluate brain specimens from an established mouse model of AD, the tq2576 mouse model of cerebral amyloid overexpression (APP), in comparison to their non-transgenic (NTG) littermates. These animals were either on a CR or ad libitum (AL) diet, and specimens were collected at two time points (5 and 15 months of age). Tissue from this cohorts of mice have already undergone microbiome analysis, and await coordinated brain and peripheral tissue assessments. Future analysis will include metabolomics, RNA-seq, and microarray data to assess the gut-brain microbiome system in neurodegenerative disorders. |
| Institute | University of North Carolina |
| Laboratory | Sumner Lab |
| Last Name | Sumner |
| First Name | Susan |
| Address | Eastern Regional Comprehensive Metabolomics Resource Core, UNC Nutrition Research Institute, 500 Laureate Way, Kannapolis, NC, 28081 |
| susan_sumner @unc.edu | |
| Phone | 704-250-5066 |
| Submit Date | 2016-09-07 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | 1r |
| Analysis Type Detail | NMR |
| Release Date | 2017-10-03 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Murine; Subject species: Mus musculus (Factor headings shown in green)
| mb_sample_id | local_sample_id | Age | Genotype | Gender | Diet |
|---|---|---|---|---|---|
| SA023268 | B_13 | 15 | APP | F | AL |
| SA023269 | B_11 | 15 | APP | F | AL |
| SA023270 | B_12 | 15 | APP | F | AL |
| SA023271 | B_14 | 15 | APP | F | AL |
| SA023272 | B_17 | 15 | APP | F | CR |
| SA023273 | B_18 | 15 | APP | F | CR |
| SA023274 | B_16 | 15 | APP | F | CR |
| SA023275 | B_15 | 15 | APP | F | CR |
| SA023276 | B_47 | 15 | APP | M | AL |
| SA023277 | B_50 | 15 | APP | M | AL |
| SA023278 | B_48 | 15 | APP | M | AL |
| SA023279 | B_49 | 15 | APP | M | AL |
| SA023280 | B_53 | 15 | APP | M | CR |
| SA023281 | B_52 | 15 | APP | M | CR |
| SA023282 | B_51 | 15 | APP | M | CR |
| SA023283 | B_54 | 15 | APP | M | CR |
| SA023284 | B_30 | 15 | NTG | F | AL |
| SA023285 | B_31 | 15 | NTG | F | AL |
| SA023286 | B_32 | 15 | NTG | F | AL |
| SA023287 | B_29 | 15 | NTG | F | AL |
| SA023288 | B_35 | 15 | NTG | F | CR |
| SA023289 | B_33 | 15 | NTG | F | CR |
| SA023290 | B_34 | 15 | NTG | F | CR |
| SA023291 | B_36 | 15 | NTG | F | CR |
| SA023292 | B_66 | 15 | NTG | M | AL |
| SA023293 | B_67 | 15 | NTG | M | AL |
| SA023294 | B_68 | 15 | NTG | M | AL |
| SA023295 | B_65 | 15 | NTG | M | AL |
| SA023296 | B_72 | 15 | NTG | M | CR |
| SA023297 | B_71 | 15 | NTG | M | CR |
| SA023298 | B_69 | 15 | NTG | M | CR |
| SA023299 | B_70 | 15 | NTG | M | CR |
| SA023300 | B_5 | 5 | APP | F | AL |
| SA023301 | B_4 | 5 | APP | F | AL |
| SA023302 | B_2 | 5 | APP | F | AL |
| SA023303 | B_1 | 5 | APP | F | AL |
| SA023304 | B_3 | 5 | APP | F | AL |
| SA023305 | B_8 | 5 | APP | F | CR |
| SA023306 | B_10 | 5 | APP | F | CR |
| SA023307 | B_6 | 5 | APP | F | CR |
| SA023308 | B_7 | 5 | APP | F | CR |
| SA023309 | B_9 | 5 | APP | F | CR |
| SA023310 | B_41 | 5 | APP | M | AL |
| SA023311 | B_37 | 5 | APP | M | AL |
| SA023312 | B_38 | 5 | APP | M | AL |
| SA023313 | B_39 | 5 | APP | M | AL |
| SA023314 | B_40 | 5 | APP | M | AL |
| SA023315 | B_46 | 5 | APP | M | CR |
| SA023316 | B_43 | 5 | APP | M | CR |
| SA023317 | B_42 | 5 | APP | M | CR |
| SA023318 | B_44 | 5 | APP | M | CR |
| SA023319 | B_45 | 5 | APP | M | CR |
| SA023320 | B_20 | 5 | NTG | F | AL |
| SA023321 | B_22 | 5 | NTG | F | AL |
| SA023322 | B_23 | 5 | NTG | F | AL |
| SA023323 | B_19 | 5 | NTG | F | AL |
| SA023324 | B_21 | 5 | NTG | F | AL |
| SA023325 | B_27 | 5 | NTG | F | CR |
| SA023326 | B_28 | 5 | NTG | F | CR |
| SA023327 | B_26 | 5 | NTG | F | CR |
| SA023328 | B_25 | 5 | NTG | F | CR |
| SA023329 | B_24 | 5 | NTG | F | CR |
| SA023330 | B_55 | 5 | NTG | M | AL |
| SA023331 | B_58 | 5 | NTG | M | AL |
| SA023332 | B_57 | 5 | NTG | M | AL |
| SA023333 | B_56 | 5 | NTG | M | AL |
| SA023334 | B_59 | 5 | NTG | M | AL |
| SA023335 | B_63 | 5 | NTG | M | CR |
| SA023336 | B_60 | 5 | NTG | M | CR |
| SA023337 | B_62 | 5 | NTG | M | CR |
| SA023338 | B_64 | 5 | NTG | M | CR |
| SA023339 | B_61 | 5 | NTG | M | CR |
| SA023340 | BP_1 | Pool | Pool | Pool | Pool |
| SA023341 | BP_2 | Pool | Pool | Pool | Pool |
| SA023342 | BP_6 | Pool | Pool | Pool | Pool |
| SA023343 | BP_5 | Pool | Pool | Pool | Pool |
| SA023344 | BP_4 | Pool | Pool | Pool | Pool |
| SA023345 | BP_3 | Pool | Pool | Pool | Pool |
| Showing results 1 to 78 of 78 |
