Summary of Study ST000528
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000388. The data can be accessed directly via it's Project DOI: 10.21228/M8WP4C This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST000528 |
| Study Title | Regulation of Metabolism by LSR |
| Study Type | LC-MS lipidomics |
| Study Summary | Our aim is to identify the LSR-driven metabolomics profile of breast cancer cells in lean and obesogenic environments. Breast cancer cell models with high or undetectable levels of LSR, including drug resistance models, were cultured in lean and obesogenic environments and comprehensive metabolomics profiling, including lipidomics-focused sub-analyses were performed. The metabolomics analyses using both approaches will help us determine if LSR enhances aggressive breast cancer phenotypes via modulation of cellular bioenergetic metabolism, ultimately contributing to poor patient outcome. |
| Institute | University of North Carolina |
| Department | Systems and Translational Sciences |
| Laboratory | Sumner Lab |
| Last Name | Sumner |
| First Name | Susan |
| Address | Eastern Regional Comprehensive Metabolomics Resource Core, UNC Nutrition Research Institute, 500 Laureate Way, Kannapolis, NC, 28081 |
| susan_sumner @unc.edu | |
| Phone | 704-250-5066 |
| Submit Date | 2016-12-29 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | raw(Thermo) |
| Analysis Type Detail | LC-MS |
| Release Date | 2018-02-07 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Cells; Subject species: Homo sapiens (Factor headings shown in green)
| mb_sample_id | local_sample_id | Cell Line |
|---|---|---|
| SA027764 | POS_Lip_S_37_LSRH-L4 | Hs578t+ |
| SA027765 | POS_Lip_S_40_LSRH-L10 | Hs578t+ |
| SA027766 | POS_Lip_S_39_LSRH-L8 | Hs578t+ |
| SA027767 | POS_Lip_S_38_LSRH-L6 | Hs578t+ |
| SA027768 | POS_Lip_S_36_LSRH-L2 | Hs578t+ |
| SA027759 | POS_Lip_S_31_HS2 | Hs578t parental |
| SA027760 | POS_Lip_S_33_HS#2 | Hs578t parental |
| SA027761 | POS_Lip_S_35_HS#2 | Hs578t parental |
| SA027762 | POS_Lip_S_32_HS | Hs578t parental |
| SA027763 | POS_Lip_S_34_HS#2 | Hs578t parental |
| SA027769 | POS_Lip_S_27_MCF7-CRISPR | MCF7 CRISPR |
| SA027770 | POS_Lip_S_26_MCF7-CRISPR | MCF7 CRISPR |
| SA027771 | POS_Lip_S_28_MCF7-CRISPR | MCF7 CRISPR |
| SA027772 | POS_Lip_S_29-2_MCF7-CRISPR | MCF7 CRISPR |
| SA027773 | POS_Lip_S_30_MCF7-CRISPR | MCF7 CRISPR |
| SA027774 | POS_Lip_S_23_MCF7 | MCF7 parental |
| SA027775 | POS_Lip_S_25_MCF7 | MCF7 parental |
| SA027776 | POS_Lip_S_22_MCF7-2 | MCF7 parental |
| SA027777 | POS_Lip_S_21_MCF7-1 | MCF7 parental |
| SA027778 | POS_Lip_S_24_MCF7 | MCF7 parental |
| SA027779 | POS_Lip_P_30_JFtotPool3 | Study Pool |
| SA027780 | POS_Lip_P_29_JFtotPool2 | Study Pool |
| SA027781 | POS_Lip_P_31_JFtotPool4 | Study Pool |
| SA027782 | POS_Lip_P_32_JFtotPool5 | Study Pool |
| SA027783 | POS_Lip_P_33_JFtotPool6 | Study Pool |
| SA027784 | POS_Lip_EQ_P28_JFtotPool1-6 | Study Pool |
| Showing results 1 to 26 of 26 |
