Summary of Study ST001186

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000798. The data can be accessed directly via it's Project DOI: 10.21228/M8J399 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001186
Study TitleUntargeted metabolomics on control and compound-treated STHdhQ111 cells and control STHdhQ7 cells
Study SummaryCells expressing mutant huntingtin were treated in triplicate with serum-free DMEM with vehicle (Q111SST) or serum-free DMEM with one of 14 protective compounds for 24 hours. Wild type cells were also treated with serum-free DMEM with vehicle (Q7SST) as an additional control for 24 hours. We examined the compounds' metabolomic effects on the cells using untargeted mass spectrometry, which measured lipids and polar metabolites.
Institute
Massachusetts Institute of Technology
LaboratoryFraenkel Lab
Last NamePatel-Murray
First NameNatasha
Address77 Massachusetts Avenue, Building 16 Room 244
Emailnlpm@mit.edu
Phone6179490941
Submit Date2019-05-24
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2020-01-22
Release Version1
Natasha Patel-Murray Natasha Patel-Murray
https://dx.doi.org/10.21228/M8J399
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Cultured cells; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id Time Treatment
SA082420DOP_21 4-Deoxypyridoxine
SA082421Clio_11 Clioquinol
SA082422Cypro_11 Cyproheptadine
SA082423Cyst_21 Cysteamine
SA082424DKI_11 Diacylglycerol kinase inhibitor II
SA082425Dime_31 Dimethyl fumarate
SA082426FTYP_31 Fingolimod phosphate
SA082427Halo_31 Haloperidol
SA082428Lox_21 Loxapine
SA082429Mec_31 Meclizine
SA082430Nico_21 Nicotinamide
SA082431Nort_21 Nortriptyline
SA082432Pizo_31 Pizotifen
SA082433Q111SST_11 Q111SST_Control
SA082434Q7SST_11 Q7SST_Control
SA082435Seli_11 Selisistat
SA082436NaB_21 Sodium Butyrate
SA082437TSA_31 Trichostatin A
SA082438DOP_32 4-Deoxypyridoxine
SA082439Clio_22 Clioquinol
SA082440Cypro_22 Cyproheptadine
SA082441Cyst_32 Cysteamine
SA082442DKI_22 Diacylglycerol kinase inhibitor II
SA082443Dime_12 Dimethyl fumarate
SA082444FTYP_12 Fingolimod phosphate
SA082445Halo_12 Haloperidol
SA082446Lox_32 Loxapine
SA082447Mec_12 Meclizine
SA082448Nico_32 Nicotinamide
SA082449Nort_32 Nortriptyline
SA082450Pizo_12 Pizotifen
SA082451Q111SST_22 Q111SST_Control
SA082452Q7SST_22 Q7SST_Control
SA082453Seli_22 Selisistat
SA082454NaB_32 Sodium Butyrate
SA082455TSA_12 Trichostatin A
SA082456DOP_13 4-Deoxypyridoxine
SA082457Clio_33 Clioquinol
SA082458Cypro_33 Cyproheptadine
SA082459Cyst_13 Cysteamine
SA082460DKI_33 Diacylglycerol kinase inhibitor II
SA082461Dime_23 Dimethyl fumarate
SA082462FTYP_23 Fingolimod phosphate
SA082463Halo_23 Haloperidol
SA082464Lox_13 Loxapine
SA082465Mec_23 Meclizine
SA082466Nico_13 Nicotinamide
SA082467Nort_13 Nortriptyline
SA082468Pizo_23 Pizotifen
SA082469Q111SST_33 Q111SST_Control
SA082470Q7SST_33 Q7SST_Control
SA082471Seli_33 Selisistat
SA082472NaB_13 Sodium Butyrate
SA082473TSA_23 Trichostatin A
Showing results 1 to 54 of 54
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