Summary of Study ST001736

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001110. The data can be accessed directly via it's Project DOI: 10.21228/M8739H This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST001736
Study Title	The COVIDome Explorer Researcher Portal (blood plasma)
Study Summary	COVID-19 pathology involves dysregulation of diverse molecular, cellular, and physiological processes. In order to expedite integrated and collaborative COVID-19 research, we completed multi-omics analysis of hospitalized COVID-19 patients including matched analysis of the whole blood transcriptome, plasma proteomics with two complementary platforms, cytokine profiling, plasma and red blood cell metabolomics, deep immune cell phenotyping by mass cytometry, and clinical data annotation. We refer to this multidimensional dataset as the COVIDome. We then created the COVIDome Explorer, an online researcher portal where the data can be analyzed and visualized in real time. We illustrate here the use of the COVIDome dataset through a multi-omics analysis of biosignatures associated with C-reactive protein (CRP), an established marker of poor prognosis in COVID-19, revealing associations between CRP levels and damage-associated molecular patterns, depletion of protective serpins, and mitochondrial metabolism dysregulation. We expect that the COVIDome Explorer will rapidly accelerate data sharing, hypothesis testing, and discoveries worldwide.
Institute	University of Colorado Anschutz Medical Campus
Last Name	Haines
First Name	Julie
Address	12801 E 17th Ave, Room 1303
Email	julie.haines@cuanschutz.edu
Phone	3037243339
Submit Date	2021-03-30
Raw Data Available	Yes
Raw Data File Type(s)	raw(Thermo)
Analysis Type Detail	LC-MS
Release Date	2021-04-09
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id	local_sample_id	COVID_Status	Sex	Age
SA162772	CUcovID_0037	Negative	Female	30
SA162773	CUcovID_0094	Negative	Female	31
SA162774	CUcovID_0079	Negative	Female	34
SA162775	CUcovID_0028	Negative	Female	34
SA162776	CUcovID_0027	Negative	Female	36
SA162777	CUcovID_0017	Negative	Female	36
SA162778	CUcovID_0039	Negative	Female	38
SA162779	CUcovID_0038	Negative	Female	39
SA162780	CUcovID_0006	Negative	Female	41
SA162781	CUcovID_0063	Negative	Female	43
SA162782	CUcovID_0095	Negative	Female	76
SA162783	CUcovID_0044	Negative	Female	80
SA162784	CUcovID_0086	Negative	Male	23
SA162785	CUcovID_0081	Negative	Male	25
SA162786	CUcovID_0084	Negative	Male	25
SA162787	CUcovID_0093	Negative	Male	26
SA162788	CUcovID_0091	Negative	Male	35
SA162789	CUcovID_0004	Negative	Male	38
SA162790	CUcovID_0051	Negative	Male	42
SA162791	CUcovID_0052	Negative	Male	43
SA162792	CUcovID_0083	Negative	Male	47
SA162793	CUcovID_0031	Negative	Male	50
SA162794	CUcovID_0073	Negative	Male	54
SA162795	CUcovID_0105	Negative	Male	59
SA162796	CUcovID_0048	Negative	Male	60
SA162797	CUcovID_0023	Negative	Male	63
SA162798	CUcovID_0076	Negative	Male	65
SA162799	CUcovID_0064	Negative	Male	66
SA162800	CUcovID_0072	Negative	Male	67
SA162801	CUcovID_0097	Negative	Male	71
SA162802	CUcovID_0082	Negative	Male	under 20
SA162803	CUcovID_0087	Positive	Female	21
SA162804	CUcovID_0106	Positive	Female	21
SA162805	CUcovID_0100	Positive	Female	23
SA162806	CUcovID_0035	Positive	Female	23
SA162807	CUcovID_0009	Positive	Female	25
SA162808	CUcovID_0003	Positive	Female	29
SA162809	CUcovID_0033	Positive	Female	29
SA162810	CUcovID_0080	Positive	Female	35
SA162811	CUcovID_0060	Positive	Female	38
SA162812	CUcovID_0022	Positive	Female	39
SA162813	CUcovID_0008	Positive	Female	39
SA162814	CUcovID_0075	Positive	Female	41
SA162815	CUcovID_0090	Positive	Female	43
SA162816	CUcovID_0002	Positive	Female	44
SA162817	CUcovID_0018	Positive	Female	45
SA162818	CUcovID_0045	Positive	Female	46
SA162819	CUcovID_0077	Positive	Female	49
SA162820	CUcovID_0071	Positive	Female	49
SA162821	CUcovID_0014	Positive	Female	53
SA162822	CUcovID_0026	Positive	Female	53
SA162823	CUcovID_0055	Positive	Female	54
SA162824	CUcovID_0025	Positive	Female	56
SA162825	CUcovID_0069	Positive	Female	56
SA162826	CUcovID_0102	Positive	Female	57
SA162827	CUcovID_0019	Positive	Female	60
SA162828	CUcovID_0074	Positive	Female	61
SA162829	CUcovID_0040	Positive	Female	61
SA162830	CUcovID_0050	Positive	Female	under 20
SA162831	CUcovID_0085	Positive	Female	under 20
SA162832	CUcovID_0092	Positive	Female	under 20
SA162833	CUcovID_0088	Positive	Female	under 20
SA162834	CUcovID_0024	Positive	Female	under 20
SA162835	CUcovID_0078	Positive	Female	under 20
SA162836	CUcovID_0101	Positive	Male	20
SA162837	CUcovID_0043	Positive	Male	21
SA162838	CUcovID_0021	Positive	Male	24
SA162839	CUcovID_0107	Positive	Male	26
SA162840	CUcovID_0007	Positive	Male	28
SA162841	CUcovID_0109	Positive	Male	30
SA162842	CUcovID_0041	Positive	Male	33
SA162843	CUcovID_0065	Positive	Male	34
SA162844	CUcovID_0016	Positive	Male	41
SA162845	CUcovID_0013	Positive	Male	42
SA162846	CUcovID_0012	Positive	Male	42
SA162847	CUcovID_0096	Positive	Male	43
SA162848	CUcovID_0108	Positive	Male	45
SA162849	CUcovID_0054	Positive	Male	46
SA162850	CUcovID_0029	Positive	Male	47
SA162851	CUcovID_0020	Positive	Male	50
SA162852	CUcovID_0049	Positive	Male	50
SA162853	CUcovID_0061	Positive	Male	51
SA162854	CUcovID_0068	Positive	Male	52
SA162855	CUcovID_0046	Positive	Male	54
SA162856	CUcovID_0042	Positive	Male	55
SA162857	CUcovID_0059	Positive	Male	55
SA162858	CUcovID_0047	Positive	Male	59
SA162859	CUcovID_0089	Positive	Male	60
SA162860	CUcovID_0030	Positive	Male	60
SA162861	CUcovID_0098	Positive	Male	61
SA162862	CUcovID_0005	Positive	Male	61
SA162863	CUcovID_0070	Positive	Male	69
SA162864	CUcovID_0010	Positive	Male	71
SA162865	CUcovID_0001	Positive	Male	77
SA162866	CUcovID_0104	Positive	Male	79
SA162867	CUcovID_0011	Positive	Male	79
SA162868	CUcovID_0067	Positive	Male	under 20
SA162869	CUcovID_0066	Positive	Male	under 20
SA162870	CUcovID_0036	Positive	Male	under 20
SA162871	CUcovID_0057	Positive	Male	under 20