Summary of Study ST001909

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001203. The data can be accessed directly via it's Project DOI: 10.21228/M86Q68 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001909
Study TitleATF3 regulation of serine metabolism
Study Typestable isotope tracing
Study SummaryATF3 is a common stress sensor, and its expression can be induced by serine deprivation. The goal of this project is to determine whether ATF3 regulates serine biosynthesis. ATF3-wildtype and –knockout cells are cultured in complete or serine-free medium supplemented with 13C-6-glucose for 24 h for stable isotope tracing. The results show that ATF3 appears to promote serine biosynthesis.
Institute
Augusta University
Last NameYan
First NameChunhong
Address1410 Laney Walker Blvd, Augusta, GA, 30912, USA
Emailcyan@augusta.edu
Phone7067210099
Submit Date2021-08-11
Raw Data AvailableYes
Raw Data File Type(s)d
Analysis Type DetailGC-MS
Release Date2021-10-02
Release Version1
Chunhong Yan Chunhong Yan
https://dx.doi.org/10.21228/M86Q68
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Cultured cells; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Genotype_Media supplement
SA176874Ding_C-3_015KO-complete
SA176875Ding_C-4_016KO-complete
SA176876Ding_C-6_018KO-complete
SA176877Ding_C-2_014KO-complete
SA176878Ding_C-5_017KO-complete
SA176879Ding_C-1_013KO-complete
SA176880Ding_D-2_020KO-serine(-)
SA176881Ding_D-1_019KO-serine(-)
SA176882Ding_D-3_021KO-serine(-)
SA176883Ding_D-4_022KO-serine(-)
SA176884Ding_D-5_023KO-serine(-)
SA176885Ding_D-6_024KO-serine(-)
SA176886Ding_A-3_003WT-complete
SA176887Ding_A-2_002WT-complete
SA176888Ding_A-4_004WT-complete
SA176889Ding_A-5_005WT-complete
SA176890Ding_A-6_006WT-complete
SA176891Ding_A-1_001WT-complete
SA176892Ding_B-4_010WT-serine(-)
SA176893Ding_B-3_009WT-serine(-)
SA176894Ding_B-5_011WT-serine(-)
SA176895Ding_B-6_012WT-serine(-)
SA176896Ding_B-2_008WT-serine(-)
SA176897Ding_B-1_007WT-serine(-)
Showing results 1 to 24 of 24
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