Summary of Study ST002462

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001589. The data can be accessed directly via it's Project DOI: 10.21228/M89H8W This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002462
Study TitleTryptophan metabolites in human sera on a defined diet
Study SummaryTrp metabolites circulating in serum could provide insight into homeostatic activity of AHR, and we wished to know if the observations in mice could be replicated in humans. Previous work by our group identified AHR activators in human feces, yet it is not clear if these activators are also present in circulation. To address this question, we quantified Trp metabolites in human serum. To mitigate the variable effect of diet on metabolite profiles, we analyzed sera samples collected from study participants fed a defined diet. As with the previously discussed mouse sera, targeted metabolomics was performed on serum samples using LC-MS.
Institute
Pennsylvania State University
Last NameDONG
First NameFANGCONG
Address309 Life Sciences Building, University Park, PA 16802
Emailfxd93@psu.edu
Phone8146990203
Submit Date2023-01-27
Raw Data AvailableYes
Raw Data File Type(s)mzML
Analysis Type DetailLC-MS
Release Date2023-02-06
Release Version1
FANGCONG DONG FANGCONG DONG
https://dx.doi.org/10.21228/M89H8W
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id diluted factor
SA246379std51
SA246380std31
SA246381std11
SA246382std61
SA246383std21
SA246384std41
SA246385std71
SA246386std101
SA246387std91
SA246388std81
SA24638916DP12.5
SA24639030DP12.5
SA24639162DP12.5
SA24639240DP32.5
SA24639351DP12.5
SA24639463DP32.5
SA24639563DP22.5
SA24639630DP22.5
SA24639760DP32.5
SA24639847DP12.5
SA24639929DP22.5
SA24640014DP12.5
SA24640112DP12.5
SA24640252DP32.5
SA24640325DP22.5
SA24640462DP32.5
SA24640529DP12.5
SA24640658DP32.5
SA24640758DP22.5
SA24640837DP22.5
SA24640920DP22.5
SA24641017DP12.5
SA24641114DP22.5
SA24641252DP12.5
SA24641325DP32.5
SA24641412DP32.5
SA24641554DP32.5
SA24641661DP22.5
SA24641760DP22.5
SA24641847DP22.5
SA24641917DP22.5
SA24642020DP32.5
SA24642155DP12.5
SA24642261DP12.5
SA24642337DP32.5
SA24642454DP22.5
SA24642555DP22.5
SA24642640DP12.5
SA24642750DP32.5
SA24642816DP32.5
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