Summary of Study ST002744

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001509. The data can be accessed directly via it's Project DOI: 10.21228/M8N71K This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002744
Study TitleBiomolecular condensates create phospholipid-enriched microenvironments (Part 4)
Study SummaryProteins and RNA are able to phase separate from the aqueous cellular environment to form sub-cellular compartments called condensates. This process results in a protein-RNA mixture that is chemically distinct from the surrounding aqueous phase. Here we use mass spectrometry to characterize the metabolomes of condensates. To test this, we prepared mixtures of phase-separated proteins and cellular metabolites and identified metabolites enriched in the condensate phase. Here, we confirmed the presence of lipids in MED1 samples and condensates using reversed-phase LC-MS.
Institute
Cornell University
Last NameDumelie
First NameJason
Address1300 York Ave, LC-524, New York City, NY
Emailsrj2003@med.cornell.edu
Phone6466590174
Submit Date2023-06-05
Raw Data AvailableYes
Raw Data File Type(s)mzdata.xml
Analysis Type DetailLC-MS
Release Date2023-07-07
Release Version1
Jason Dumelie Jason Dumelie
https://dx.doi.org/10.21228/M8N71K
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id fraction Extraction from condensate
SA289160MED1 Aqueous Sample 6aqueous No heat step
SA289161MED1 Aqueous Sample 5aqueous No heat step
SA289162MED1 Aqueous Sample 4aqueous No heat step
SA289163MED1 Aqueous Sample 9aqueous standard
SA289164MED1 Aqueous Sample 8aqueous standard
SA289165MED1 Aqueous Sample 7aqueous standard
SA289166MED1 Condensate Sample 6condensate No heat step
SA289167MED1 Condensate Sample 5condensate No heat step
SA289168MED1 Condensate Sample 4condensate No heat step
SA289169MED1 Condensate Sample 9condensate standard
SA289170MED1 Condensate Sample 7condensate standard
SA289171MED1 Condensate Sample 8condensate standard
SA289172MED1 Input Sample 4input No heat step
SA289173MED1 Input Sample 6input No heat step
SA289174MED1 Input Sample 5input No heat step
SA289175MED1 Input Sample 9input standard
SA289176MED1 Input Sample 7input standard
SA289177MED1 Input Sample 8input standard
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