Summary of Study ST001858
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001163. The data can be accessed directly via it's Project DOI: 10.21228/M8CH74 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001858 |
| Study Title | Proteasome Inhibitor Related Cardiotoxicity (part II) |
| Study Summary | BALB/c mice were injected with CFZ (16 mg/kg, iv), BTZ (1 mg/kg, iv), CFZ/atRA (CFZ: 16 mg/kg iv, atRA: 1 mg/kg iv) or Captisol (Vehicle, iv) (6 mice per cohort). ECGs were recorded under anesthesia at the end of 1h treatment and the mice were sacrificed by cervical dislocation. Plasma was obtained after centrifugation by heart puncture. Samples were immediately frozen and stored at -80°C until analysis |
| Institute | University of Zurich |
| Last Name | Mendez |
| First Name | Max |
| Address | Rorschacherstrasse 95. 9007, St.Gallen |
| maxmendez@runbox.com | |
| Phone | +41 71 494 10 67 |
| Submit Date | 2021-06-27 |
| Num Groups | 4 |
| Total Subjects | 24 |
| Num Females | 24 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | mzXML |
| Analysis Type Detail | LC-MS |
| Release Date | 2022-06-01 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Project:
| Project ID: | PR001163 |
| Project DOI: | doi: 10.21228/M8CH74 |
| Project Title: | Proteasome Inhibitor Related Cardiotoxicity |
| Project Type: | MS Untargeted Metabolomics from Murine Hearts |
| Project Summary: | In this study we aimed to examine the acute metabolomic changes following proteasome inhibition with Bortezomib or Carfilzomib in murine heart. |
| Institute: | University of Zurich |
| Department: | Department of Hematology-Oncology. Kantonsspital St. Gallen |
| Laboratory: | Experimental Hematolgy-KSSG |
| Last Name: | Mendez |
| First Name: | Max |
| Address: | Rorschacherstrasse 95, 9007, St. Gallen. |
| Email: | maxmendez@runbox.com |
| Phone: | +41 71 494 10 67 |
