Summary of Study ST002156
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001369. The data can be accessed directly via it's Project DOI: 10.21228/M8RQ67 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST002156 |
| Study Title | Mouse liver metabolites |
| Study Summary | Western diet (WD) and gut microbiota interplay drives the development of non-alcoholic fatty liver disease (NAFLD) and its progression to non-alcoholic steatohepatitis (NASH). However, the metabolic mediators contributing to NASH remain to be identified. In this study, we explored the change of liver metabolites in a diet-induced mouse NASH model. Identification of these metabolites will help to uncover the pathogenesis of NASH and explore the new therapeutic treatment. |
| Institute | University of Missouri-Columbia |
| Last Name | Yang |
| First Name | Ming |
| Address | University of Missouri |
| yangmin@health.missouri.edu | |
| Phone | 5738827141 |
| Submit Date | 2022-04-24 |
| Analysis Type Detail | GC-MS |
| Release Date | 2022-05-16 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Sample Preparation:
| Sampleprep ID: | SP002248 |
| Sampleprep Summary: | Briefly, liver tissues (50-100 mg) are typically homogenized in the extraction solvent using a bead beater. These samples are then centrifuged at 13,000 g for 15 min to pellet tissue and proteins. The supernatant is combined with water and chloroform, including internal standards, to separate into the polar and non-polar phases. |
| Processing Storage Conditions: | -80℃ |
| Extract Storage: | -80℃ |
